Best practices in secondary fracture prevention: fracture liaison services.

Fracture Liaison Services (FLS) have been demonstrated in many countries to provide an effective means to deliver secondary preventive care for patients presenting with fragility fractures. This review provides an update on journal articles, reports, guidelines and government policies, with relevance to FLS, which have been published during the period 2009-2012. International evidence of the extent and persistence of the secondary fracture prevention care gap has expanded during this period. Major professional and patient societies throughout the world, including the International Osteoporosis Foundation and the American Society for Bone and Mineral Research, have supported international initiatives to disseminate best practice. Health economic analysis of FLS has developed considerably, with a consistent theme from investigator-led and government analyses that FLS provide highly cost-effective care. Opportunities to close the care gap, in a systematic way, for unrecognised vertebral fracture sufferers are also considered.