Literature DB >> 23306822

Pediatric radiation dose and risk from bone density measurements using a GE Lunar Prodigy scanner.

J Damilakis1, G Solomou, G E Manios, A Karantanas.   

Abstract

UNLABELLED: Effective radiation doses associated with bone mineral density examinations performed on children using a GE Lunar Prodigy fan-beam dual-energy X-ray absorptiometry (DXA) scanner were found to be comparable to doses from pencil-beam DXA devices, i.e., lower than 1 μSv. Cancer risks associated with acquisitions obtained in this study are negligible.
INTRODUCTION: No data were found in the literature on radiation doses and potential risks following pediatric DXA performed on GE Lunar DXA scanners. This study aimed to estimate effective doses and associated cancer risks involved in pediatric examinations performed on a GE Lunar Prodigy scanner.
METHODS: Four physical anthropomorphic phantoms representing newborn, 1-, 5-, and 10-year-old patients were employed to simulate DXA exposures. All acquisitions were carried out using the Prodigy scanner. Dose measurements were performed for spine and dual femur using the phantoms simulating the 5- and 10-year-old child. Moreover, doses associated with whole-body examinations were measured for the four phantoms used in the current study.
RESULTS: The gender-average effective dose for spine and hip examinations were 0.65 and 0.36 μSv, respectively, for the phantom representing the 5-year-old child and 0.93 and 0.205 μSv, respectively, for the phantom representing the 10-year-old child. Effective doses for whole-body examinations were 0.25, 0.22, 0.19, and 0.15 μSv for the neonate, 1-, 5-, and 10-year old child, respectively. The estimated lifetime cancer risks were negligible, i.e., 0.02-0.25 per million, depending on the sex, age, and type of DXA examination. A formula is presented for the estimation of effective dose from examinations performed on GE Lunar Prodigy scanners installed in other institutions.
CONCLUSIONS: The effective doses and potential cancer risks associated with pediatric DXA examinations performed on a GE Lunar Prodigy fan-beam scanner were found to be comparable to doses and risks reported from pencil-beam DXA devices.

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Year:  2013        PMID: 23306822     DOI: 10.1007/s00198-012-2261-x

Source DB:  PubMed          Journal:  Osteoporos Int        ISSN: 0937-941X            Impact factor:   4.507


  17 in total

1.  Axial and total-body bone densitometry using a narrow-angle fan-beam.

Authors:  R B Mazess; J A Hanson; R Payne; R Nord; M Wilson
Journal:  Osteoporos Int       Date:  2000       Impact factor: 4.507

2.  Assessing body composition in healthy newborn infants: reliability of dual-energy x-ray absorptiometry.

Authors:  Kristin Godang; Elisabeth Qvigstad; Nanna Voldner; Gunhild A Isaksen; Kathrine F Frøslie; Jacob Nøtthellen; Tore Henriksen; Jens Bollerslev
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3.  The 2007 Recommendations of the International Commission on Radiological Protection. ICRP publication 103.

Authors: 
Journal:  Ann ICRP       Date:  2007

4.  Technical considerations of dual-energy X-ray absorptiometry-based bone mineral measurements for pediatric studies.

Authors:  W W Koo; J Walters; A J Bush
Journal:  J Bone Miner Res       Date:  1995-12       Impact factor: 6.741

5.  Radiation dose and in vitro precision in paediatric bone mineral density measurement using dual X-ray absorptiometry.

Authors:  C F Njeh; S B Samat; A Nightingale; E A McNeil; C M Boivin
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Review 6.  Radiation exposure in X-ray-based imaging techniques used in osteoporosis.

Authors:  John Damilakis; Judith E Adams; Giuseppe Guglielmi; Thomas M Link
Journal:  Eur Radiol       Date:  2010-06-18       Impact factor: 5.315

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Authors:  Sundeep Khosla; L Joseph Melton; Mark B Dekutoski; Sara J Achenbach; Ann L Oberg; B Lawrence Riggs
Journal:  JAMA       Date:  2003-09-17       Impact factor: 56.272

Review 9.  Methods for measurement of pediatric bone.

Authors:  Teresa L Binkley; Ryan Berry; Bonny L Specker
Journal:  Rev Endocr Metab Disord       Date:  2008-02-05       Impact factor: 6.514

10.  Effective dose of dual-energy X-ray absorptiometry scans in children as a function of age.

Authors:  Stephen R Thomas; Heidi J Kalkwarf; Donna D Buckley; James E Heubi
Journal:  J Clin Densitom       Date:  2005       Impact factor: 2.963

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3.  Effect of a program of short bouts of exercise on bone health in adolescents involved in different sports: the PRO-BONE study protocol.

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