Literature DB >> 23212972

Substrate specificity in ketosynthase domains from trans-AT polyketide synthases.

Matthew Jenner1, Sarah Frank, Annette Kampa, Christoph Kohlhaas, Petra Pöplau, Geoff S Briggs, Jörn Piel, Neil J Oldham.   

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Year:  2012        PMID: 23212972     DOI: 10.1002/anie.201207690

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN: 1433-7851            Impact factor:   15.336


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  19 in total

1.  Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases.

Authors:  Jeremy R Lohman; Ming Ma; Jerzy Osipiuk; Boguslaw Nocek; Youngchang Kim; Changsoo Chang; Marianne Cuff; Jamey Mack; Lance Bigelow; Hui Li; Michael Endres; Gyorgy Babnigg; Andrzej Joachimiak; George N Phillips; Ben Shen
Journal:  Proc Natl Acad Sci U S A       Date:  2015-09-29       Impact factor: 11.205

Review 2.  Engineering the acyltransferase substrate specificity of assembly line polyketide synthases.

Authors:  Briana J Dunn; Chaitan Khosla
Journal:  J R Soc Interface       Date:  2013-05-29       Impact factor: 4.118

Review 3.  The Uncommon Enzymology of Cis-Acyltransferase Assembly Lines.

Authors:  Adrian T Keatinge-Clay
Journal:  Chem Rev       Date:  2017-04-10       Impact factor: 60.622

4.  A close look at a ketosynthase from a trans-acyltransferase modular polyketide synthase.

Authors:  Darren C Gay; Glen Gay; Abram J Axelrod; Matthew Jenner; Christoph Kohlhaas; Annette Kampa; Neil J Oldham; Jörn Piel; Adrian T Keatinge-Clay
Journal:  Structure       Date:  2014-02-06       Impact factor: 5.006

Review 5.  Engineering polyketide synthases and nonribosomal peptide synthetases.

Authors:  Gavin J Williams
Journal:  Curr Opin Struct Biol       Date:  2013-07-06       Impact factor: 6.809

6.  Structure and mechanistic analyses of the gating mechanism of elongating ketosynthases.

Authors:  Jeffrey T Mindrebo; Aochiu Chen; Woojoo E Kim; Rebecca N Re; Tony D Davis; Joseph P Noel; Michael D Burkart
Journal:  ACS Catal       Date:  2021-05-26       Impact factor: 13.700

7.  Spliceostatin hemiketal biosynthesis in Burkholderia spp. is catalyzed by an iron/α-ketoglutarate-dependent dioxygenase.

Authors:  Alessandra S Eustáquio; Jeffrey E Janso; Anokha S Ratnayake; Christopher J O'Donnell; Frank E Koehn
Journal:  Proc Natl Acad Sci U S A       Date:  2014-08-05       Impact factor: 11.205

8.  Metabolic and evolutionary origin of actin-binding polyketides from diverse organisms.

Authors:  Reiko Ueoka; Agustinus R Uria; Silke Reiter; Tetsushi Mori; Petra Karbaum; Eike E Peters; Eric J N Helfrich; Brandon I Morinaka; Muriel Gugger; Haruko Takeyama; Shigeki Matsunaga; Jörn Piel
Journal:  Nat Chem Biol       Date:  2015-08-03       Impact factor: 15.040

Review 9.  Stereocontrol within polyketide assembly lines.

Authors:  Adrian T Keatinge-Clay
Journal:  Nat Prod Rep       Date:  2016-02       Impact factor: 13.423

10.  Systematic analysis of the kalimantacin assembly line NRPS module using an adapted targeted mutagenesis approach.

Authors:  Birgit Uytterhoeven; Kenny Appermans; Lijiang Song; Joleen Masschelein; Thomas Lathouwers; Chris W Michiels; Rob Lavigne
Journal:  Microbiologyopen       Date:  2015-12-15       Impact factor: 3.139

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