BACKGROUND: Children diagnosed with congenital heart disease often undergo cardiac catheterization for their treatment, which involves the use of ionizing radiation and therefore a risk of radiation-induced cancer. OBJECTIVE: The purpose of this study was to calculate the effective and equivalent organ doses (H(T)) in those children and estimate the risk of exposure-induced death. MATERIALS AND METHODS: Fifty-three children were divided into three groups: atrial septal defect (ASD), ventricular septal defect (VSD) and patent ductus arteriosus (PDA). In all procedures, the exposure conditions and the dose-area product meters readings were recorded for each individual acquisition. Monte Carlo simulations were run using the PCXMC 2.0 code and mathematical phantoms simulating a child's anatomy. The H(T) values to all irradiated organs and the resulting E and risk of exposure-induced death values were calculated. RESULTS: The average dose-area product values were, respectively, 40 ± 12 Gy·cm(2) for the ASD, 17.5 ± 0.7 Gy·cm(2) for the VSD and 9.5 ± 1 Gy·cm(2) for the PDA group. The average E values were 40 ± 12, 22 ± 2.5 and 17 ± 3.6 mSv for ASD, VSD and PDA groups, respectively. The respective estimated risk of exposure-induced death values per procedure were 0.109, 0.106 and 0.067%. CONCLUSION: Cardiac catheterizations in children involve a considerable risk for radiation-induced cancer that has to be further reduced.
BACKGROUND:Children diagnosed with congenital heart disease often undergo cardiac catheterization for their treatment, which involves the use of ionizing radiation and therefore a risk of radiation-induced cancer. OBJECTIVE: The purpose of this study was to calculate the effective and equivalent organ doses (H(T)) in those children and estimate the risk of exposure-induced death. MATERIALS AND METHODS: Fifty-three children were divided into three groups: atrial septal defect (ASD), ventricular septal defect (VSD) and patent ductus arteriosus (PDA). In all procedures, the exposure conditions and the dose-area product meters readings were recorded for each individual acquisition. Monte Carlo simulations were run using the PCXMC 2.0 code and mathematical phantoms simulating a child's anatomy. The H(T) values to all irradiated organs and the resulting E and risk of exposure-induced death values were calculated. RESULTS: The average dose-area product values were, respectively, 40 ± 12 Gy·cm(2) for the ASD, 17.5 ± 0.7 Gy·cm(2) for the VSD and 9.5 ± 1 Gy·cm(2) for the PDA group. The average E values were 40 ± 12, 22 ± 2.5 and 17 ± 3.6 mSv for ASD, VSD and PDA groups, respectively. The respective estimated risk of exposure-induced death values per procedure were 0.109, 0.106 and 0.067%. CONCLUSION: Cardiac catheterizations in children involve a considerable risk for radiation-induced cancer that has to be further reduced.
Authors: B D Thanopoulos; C V Laskari; G S Tsaousis; A Zarayelyan; A Vekiou; G S Papadopoulos Journal: J Am Coll Cardiol Date: 1998-04 Impact factor: 24.094
Authors: Andrew C Glatz; Akash Patel; Xiaowei Zhu; Yoav Dori; Brian D Hanna; Matthew J Gillespie; Jonathan J Rome Journal: Pediatr Cardiol Date: 2014-01-18 Impact factor: 1.655
Authors: Jason N Johnson; Christoph P Hornik; Jennifer S Li; Daniel K Benjamin; Terry T Yoshizumi; Robert E Reiman; Donald P Frush; Kevin D Hill Journal: Circulation Date: 2014-06-09 Impact factor: 29.690
Authors: Nikolaus A Haas; Christoph M Happel; Maria Mauti; Cherif Sahyoun; Lea Z Tebart; Deniz Kececioglu; Kai Thorsten Laser Journal: Int J Cardiol Heart Vasc Date: 2015-01-20