OBJECTIVE: We sought to examine the association of labor induction and perinatal outcomes. STUDY DESIGN: This was a retrospective cohort study of low-risk nulliparous women with term, live births. Women who had induction at a given gestational age (eg, 39 weeks) were compared to delivery at a later gestation (eg, 40, 41, or 42 weeks). RESULTS: Compared to delivery at a later gestational age, those induced at 39 weeks had a lower risk of cesarean (adjusted odds ratio [aOR], 0.90; 95% confidence interval [CI], 0.88-0.91) and labor dystocia (aOR, 0.88; 95% CI, 0.84-0.94). Their neonates had lowered risk of having 5-minute Apgar <7 (aOR, 0.81; 95% CI, 0.72-0.92), meconium aspiration syndrome (aOR, 0.30; 95% CI, 0.19-0.48), and admission to neonatal intensive care unit (aOR, 0.87; 95% CI, 0.78-0.97). Similar findings were seen for women who were induced at 40 weeks compared to delivery later. CONCLUSION: Induction of labor in low-risk women at term is not associated with increased risk of cesarean delivery compared to delivery later.
OBJECTIVE: We sought to examine the association of labor induction and perinatal outcomes. STUDY DESIGN: This was a retrospective cohort study of low-risk nulliparous women with term, live births. Women who had induction at a given gestational age (eg, 39 weeks) were compared to delivery at a later gestation (eg, 40, 41, or 42 weeks). RESULTS: Compared to delivery at a later gestational age, those induced at 39 weeks had a lower risk of cesarean (adjusted odds ratio [aOR], 0.90; 95% confidence interval [CI], 0.88-0.91) and labor dystocia (aOR, 0.88; 95% CI, 0.84-0.94). Their neonates had lowered risk of having 5-minute Apgar <7 (aOR, 0.81; 95% CI, 0.72-0.92), meconium aspiration syndrome (aOR, 0.30; 95% CI, 0.19-0.48), and admission to neonatal intensive care unit (aOR, 0.87; 95% CI, 0.78-0.97). Similar findings were seen for women who were induced at 40 weeks compared to delivery later. CONCLUSION: Induction of labor in low-risk women at term is not associated with increased risk of cesarean delivery compared to delivery later.
Authors: Joyce A Martin; Brady E Hamilton; Paul D Sutton; Stephanie J Ventura; T J Mathews; Michelle J K Osterman Journal: Natl Vital Stat Rep Date: 2010-12-08
Authors: Francis P J M Vrouenraets; Frans J M E Roumen; Cary J G Dehing; Eline S A van den Akker; Maureen J B Aarts; Esther J T Scheve Journal: Obstet Gynecol Date: 2005-04 Impact factor: 7.661
Authors: Yujia Zhang; Sara Crawford; Sheree L Boulet; Michael Monsour; Bruce Cohen; Patricia McKane; Karen Freeman Journal: J Mod Appl Stat Methods Date: 2017
Authors: Jennifer L Bailit; William Grobman; Yuan Zhao; Ronald J Wapner; Uma M Reddy; Michael W Varner; Kenneth J Leveno; Steve N Caritis; Jay D Iams; Alan T Tita; George Saade; Yoram Sorokin; Dwight J Rouse; Sean C Blackwell; Jorge E Tolosa; J Peter VanDorsten Journal: Am J Obstet Gynecol Date: 2014-06-28 Impact factor: 8.661
Authors: William A Grobman; Madeline M Rice; Uma M Reddy; Alan T N Tita; Robert M Silver; Gail Mallett; Kim Hill; Elizabeth A Thom; Yasser Y El-Sayed; Annette Perez-Delboy; Dwight J Rouse; George R Saade; Kim A Boggess; Suneet P Chauhan; Jay D Iams; Edward K Chien; Brian M Casey; Ronald S Gibbs; Sindhu K Srinivas; Geeta K Swamy; Hyagriv N Simhan; George A Macones Journal: N Engl J Med Date: 2018-08-09 Impact factor: 91.245
Authors: Mary Catherine Tolcher; Alexis N Hokenstad; Amy L Weaver; Michaela E McGree; Carl H Rose; Abimbola O Famuyide; Brian C Brost Journal: Gynecol Obstet Invest Date: 2018-10-12 Impact factor: 2.729
Authors: Yasser Y El-Sayed; Madeline Murguia Rice; William A Grobman; Uma M Reddy; Alan T N Tita; Robert M Silver; Gail Mallett; Kim Hill; Elizabeth A Thom; Ronald J Wapner; Dwight J Rouse; George R Saade; John M Thorp; Suneet P Chauhan; Edward K Chien; Brian M Casey; Ronald S Gibbs; Sindhu K Srinivas; Geeta K Swamy; Hyagriv N Simhan; George A Macones Journal: Obstet Gynecol Date: 2020-10 Impact factor: 7.623