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Literature DB >> 22972824

Antimicrobial treatment and containment measures for an extremely drug-resistant Klebsiella pneumoniae ST101 isolate carrying pKPN101-IT, a novel fully sequenced bla(KPC-2) plasmid.

Ilaria Frasson¹, Enrico Lavezzo, Elisa Franchin, Stefano Toppo, Luisa Barzon, Antonietta Cavallaro, Sara N Richter, Giorgio Palù.

Abstract

An extremely drug-resistant Klebsiella pneumoniae isolate, sequence type ST101, was isolated from a patient in Italy. We describe antibiotic treatment, measures to clear and contain the infection, and a complete sequence analysis of a novel large plasmid, pKPN101-IT, harboring the bla(KPC-2) gene and arising from the threatening recombination of different worldwide-distributed backbones.

Entities: Disease Gene Species

Mesh：

Substances：

Year: 2012 PMID： 22972824 PMCID： PMC3486238 DOI： 10.1128/JCM.01892-12

Source DB: PubMed Journal: J Clin Microbiol ISSN： 0095-1137 Impact factor: 5.948

30 in total

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Journal: Int J Antimicrob Agents Date: 2012-04-23 Impact factor: 5.283

2. Molecular epidemiology of KPC-2- producing Klebsiella pneumoniae isolates in Brazil: the predominance of sequence type 437.

Authors: Liliane M Seki; Polyana S Pereira; Maria da Penha A H de Souza; Magda de S Conceição; Elizabeth A Marques; Carlos Oliveira Porto; Elvira Maria L Colnago; Carlene de F M Alves; Deize Gomes; Ana Paula D A Carvalho Assef; Ørjan Samuelsen; Marise D Asensi
Journal: Diagn Microbiol Infect Dis Date: 2011-03-11 Impact factor: 2.803

3. Activity of tigecycline alone and in combination with colistin and meropenem against Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae strains by time-kill assay.

Authors: Spyros Pournaras; Georgia Vrioni; Evangelia Neou; John Dendrinos; Evangelia Dimitroulia; Aggeliki Poulou; Athanassios Tsakris
Journal: Int J Antimicrob Agents Date: 2011-01-13 Impact factor: 5.283

4. First outbreak of a plasmid-mediated carbapenem-hydrolyzing OXA-48 beta-lactamase in Klebsiella pneumoniae in Spain.

Authors: Cristina Pitart; Mar Solé; Ignasi Roca; Anna Fàbrega; Jordi Vila; Francesc Marco
Journal: Antimicrob Agents Chemother Date: 2011-07-11 Impact factor: 5.191

5. Clonal dissemination of Klebsiella pneumoniae ST258 harbouring KPC-2 in Argentina.

Authors: S A Gomez; F G Pasteran; D Faccone; N Tijet; M Rapoport; C Lucero; O Lastovetska; E Albornoz; M Galas; R G Melano; A Corso; A Petroni
Journal: Clin Microbiol Infect Date: 2011-08-18 Impact factor: 8.067

6. Multiplex real-time PCR for detection of an epidemic KPC-producing Klebsiella pneumoniae ST258 clone.

Authors: Liang Chen; Kalyan D Chavda; José R Mediavilla; Yanan Zhao; Henry S Fraimow; Stephen G Jenkins; Michael H Levi; Tao Hong; Albert D Rojtman; Christine C Ginocchio; Robert A Bonomo; Barry N Kreiswirth
Journal: Antimicrob Agents Chemother Date: 2012-03-26 Impact factor: 5.191

7. Treatment outcome of bacteremia due to KPC-producing Klebsiella pneumoniae: superiority of combination antimicrobial regimens.

Authors: Zubair A Qureshi; David L Paterson; Brian A Potoski; Mary C Kilayko; Gabriel Sandovsky; Emilia Sordillo; Bruce Polsky; Jennifer M Adams-Haduch; Yohei Doi
Journal: Antimicrob Agents Chemother Date: 2012-01-17 Impact factor: 5.191

8. KPC-mediated resistance in Klebsiella pneumoniae in two hospitals in Padua, Italy, June 2009-December 2011: massive spreading of a KPC-3-encoding plasmid and involvement of non-intensive care units.

Authors: Sara N Richter; Ilaria Frasson; Elisa Franchin; Cristina Bergo; Enrico Lavezzo; Luisa Barzon; Antonietta Cavallaro; Giorgio Palù
Journal: Gut Pathog Date: 2012-07-16 Impact factor: 4.181

Review 9. Current epidemiology and growing resistance of gram-negative pathogens.

Authors: David M Livermore
Journal: Korean J Intern Med Date: 2012-05-31 Impact factor: 2.884

10. The RAST Server: rapid annotations using subsystems technology.

Authors: Ramy K Aziz; Daniela Bartels; Aaron A Best; Matthew DeJongh; Terrence Disz; Robert A Edwards; Kevin Formsma; Svetlana Gerdes; Elizabeth M Glass; Michael Kubal; Folker Meyer; Gary J Olsen; Robert Olson; Andrei L Osterman; Ross A Overbeek; Leslie K McNeil; Daniel Paarmann; Tobias Paczian; Bruce Parrello; Gordon D Pusch; Claudia Reich; Rick Stevens; Olga Vassieva; Veronika Vonstein; Andreas Wilke; Olga Zagnitko
Journal: BMC Genomics Date: 2008-02-08 Impact factor: 3.969

22 in total

1. Clinical Performance of a Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry Method for Detection of Certain blaKPC-Containing Plasmids.

Authors: Jung-Ho Youn; Steven K Drake; Rebecca A Weingarten; Karen M Frank; John P Dekker; Anna F Lau
Journal: J Clin Microbiol Date: 2015-09-02 Impact factor: 5.948

2. A rapid matrix-assisted laser desorption ionization-time of flight mass spectrometry-based method for single-plasmid tracking in an outbreak of carbapenem-resistant Enterobacteriaceae.

Authors: Anna F Lau; Honghui Wang; Rebecca A Weingarten; Steven K Drake; Anthony F Suffredini; Mark K Garfield; Yong Chen; Marjan Gucek; Jung-Ho Youn; Frida Stock; Hanna Tso; Jim DeLeo; James J Cimino; Karen M Frank; John P Dekker
Journal: J Clin Microbiol Date: 2014-05-21 Impact factor: 5.948

3. Tn4401 carrying blaKPC is inserted within another insertion in pKpQIL and related plasmids.

Authors: Sally R Partridge
Journal: J Clin Microbiol Date: 2014-12 Impact factor: 5.948

4. Complete sequence of a bla(KPC)-harboring cointegrate plasmid isolated from Escherichia coli.

Authors: Kalyan D Chavda; Liang Chen; Michael R Jacobs; Albert D Rojtman; Robert A Bonomo; Barry N Kreiswirth
Journal: Antimicrob Agents Chemother Date: 2015-03-09 Impact factor: 5.191

5. Complete nucleotide sequence of two multidrug-resistant IncR plasmids from Klebsiella pneumoniae.

Authors: Fabrice Compain; Lionel Frangeul; Laurence Drieux; Charlotte Verdet; Sylvain Brisse; Guillaume Arlet; Dominique Decré
Journal: Antimicrob Agents Chemother Date: 2014-04-21 Impact factor: 5.191

6. Evaluation of Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry for Identification of KPC-Producing Klebsiella pneumoniae.

Authors: Paolo Gaibani; Anna Galea; Marco Fagioni; Simone Ambretti; Vittorio Sambri; Maria Paola Landini
Journal: J Clin Microbiol Date: 2016-07-13 Impact factor: 5.948

7. Characterization of KPC-Encoding Plasmids from Enterobacteriaceae Isolated in a Czech Hospital.

Authors: Rudolf Kukla; Katerina Chudejova; Costas C Papagiannitsis; Matej Medvecky; Katerina Habalova; Lenka Hobzova; Radka Bolehovska; Lenka Pliskova; Jaroslav Hrabak; Helena Zemlickova
Journal: Antimicrob Agents Chemother Date: 2018-02-23 Impact factor: 5.191