| Literature DB >> 29263065 |
Rudolf Kukla1, Katerina Chudejova2,3, Costas C Papagiannitsis4,2,3, Matej Medvecky5,6, Katerina Habalova1, Lenka Hobzova7, Radka Bolehovska8, Lenka Pliskova8, Jaroslav Hrabak2,3, Helena Zemlickova1,9.
Abstract
Ten Enterobacteriaceae isolates collected in a Czech hospital carried blaKPC-positive plasmids of different sizes (∼30, ∼45, and ∼80 kb). Sequencing revealed three types of plasmids (A to C) with the Tn4401a transposon. Type A plasmids comprised an IncR backbone and a KPC-2-encoding multidrug resistance (MDR) region. Type B plasmids were derivatives of type A plasmids carrying an IncN3-like segment, while type C plasmids were IncP6 plasmids sharing the same KPC-2-encoding MDR region with type A and B plasmids.Entities:
Keywords: Citrobacter freundii; Illumina sequencing; IncR; ST18; Tn4401a
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Year: 2018 PMID: 29263065 PMCID: PMC5826142 DOI: 10.1128/AAC.02152-17
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191