| Literature DB >> 21851480 |
S A Gomez1, F G Pasteran, D Faccone, N Tijet, M Rapoport, C Lucero, O Lastovetska, E Albornoz, M Galas, R G Melano, A Corso, A Petroni.
Abstract
The present work describes the abrupt emergence of Klebsiella pneumoniae carbapenemase (KPC) and characterizes the first 79 KPC-producing enterobacteria from Argentina (isolated from 2006 to 2010). The emergence of bla(KPC-2) was characterized by two patterns of dispersion: the first was the sporadic occurrence in diverse enterobacteria from distant geographical regions, harbouring plasmids of different incompatibility groups and bla(KPC-2) in an unusual genetic environment flanked by ISKpn8-Δbla(TEM-1) and ISKpn6-like. bla(KPC-2) was associated with IncL/M transferable plasmids; the second was the abrupt clonal spread of K. pneumoniae ST258 harbouring bla(KPC-2) in Tn4401a.Entities:
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Year: 2011 PMID： 21851480 DOI： 10.1111/j.1469-0691.2011.03600.x
Source DB: PubMed Journal: Clin Microbiol Infect ISSN： 1198-743X Impact factor: 8.067