Literature DB >> 22821513

An integrated chip for the high-throughput synthesis of transcription activator-like effectors.

Zhao Wang1, Juan Li, Huang Huang, Gancheng Wang, Mingjun Jiang, Shenyi Yin, Changhong Sun, Hanshuo Zhang, Fengfeng Zhuang, Jianzhong Jeff Xi.   

Abstract

A TALE of two assays: Transcription activator-like effectors (TALEs) are programmable proteins that can specifically recognize a DNA sequence. Previous strategies for the synthesis of TALEs were complicated and time-consuming. The solid-phase synthesis strategy demonstrated here allows quick and simple purification of the ligation product.
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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Year:  2012        PMID： 22821513     DOI： 10.1002/anie.201203597

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  21 in total

1.  Interaction of factor H-binding protein of Streptococcus suis with globotriaosylceramide promotes the development of meningitis.

Authors:  Decong Kong; Zhe Chen; Junping Wang; Qingyu Lv; Hua Jiang; Yuling Zheng; Maokai Xu; Xuyu Zhou; Huaijie Hao; Yongqiang Jiang
Journal:  Virulence       Date:  2017-04-12       Impact factor: 5.882

Review 2.  TALENs: a widely applicable technology for targeted genome editing.

Authors:  J Keith Joung; Jeffry D Sander
Journal:  Nat Rev Mol Cell Biol       Date:  2012-11-21       Impact factor: 94.444

Review 3.  A guide to genome engineering with programmable nucleases.

Authors:  Hyongbum Kim; Jin-Soo Kim
Journal:  Nat Rev Genet       Date:  2014-04-02       Impact factor: 53.242

Review 4.  Targeted genome engineering techniques in Drosophila.

Authors:  Kelly J Beumer; Dana Carroll
Journal:  Methods       Date:  2014-01-08       Impact factor: 3.608

5.  Principles and applications of TAL effectors for plant physiology and metabolism.

Authors:  Adam J Bogdanove
Journal:  Curr Opin Plant Biol       Date:  2014-06-05       Impact factor: 7.834

6.  High‑efficiency system for construction and evaluation of customized TALENs for silkworm genome editing.

Authors:  Feng Wang; Sanyuan Ma; Hanfu Xu; Jianping Duan; Yuancheng Wang; Huan Ding; Yuanyuan Liu; Xiaogang Wang; Ping Zhao; Qingyou Xia
Journal:  Mol Genet Genomics       Date:  2013-12       Impact factor: 3.291

7.  Engineering customized TALE nucleases (TALENs) and TALE transcription factors by fast ligation-based automatable solid-phase high-throughput (FLASH) assembly.

Authors:  Deepak Reyon; Morgan L Maeder; Cyd Khayter; Shengdar Q Tsai; Jonathan E Foley; Jeffry D Sander; J Keith Joung
Journal:  Curr Protoc Mol Biol       Date:  2013-07

Review 8.  TAL effectors: highly adaptable phytobacterial virulence factors and readily engineered DNA-targeting proteins.

Authors:  Erin L Doyle; Barry L Stoddard; Daniel F Voytas; Adam J Bogdanove
Journal:  Trends Cell Biol       Date:  2013-05-23       Impact factor: 20.808

9.  Systematically labeling developmental stage-specific genes for the study of pancreatic β-cell differentiation from human embryonic stem cells.

Authors:  Haisong Liu; Huan Yang; Dicong Zhu; Xin Sui; Juan Li; Zhen Liang; Lei Xu; Zeyu Chen; Anzhi Yao; Long Zhang; Xi Zhang; Xing Yi; Meng Liu; Shiqing Xu; Wenjian Zhang; Hua Lin; Lan Xie; Jinning Lou; Yong Zhang; Jianzhong Xi; Hongkui Deng
Journal:  Cell Res       Date:  2014-09-05       Impact factor: 25.617

10.  A large-scale in vivo analysis reveals that TALENs are significantly more mutagenic than ZFNs generated using context-dependent assembly.

Authors:  Shijia Chen; Grigorios Oikonomou; Cindy N Chiu; Brett J Niles; Justin Liu; Daniel A Lee; Igor Antoshechkin; David A Prober
Journal:  Nucleic Acids Res       Date:  2013-01-08       Impact factor: 16.971
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