Literature DB >> 22729219

Structure and noncanonical chemistry of nonribosomal peptide biosynthetic machinery.

Heather L Condurso1, Steven D Bruner.   

Abstract

Structural biology has provided significant insights into the complex chemistry and macromolecular organization of nonribosomal peptide synthetases. In addition, novel pathways are continually described, expanding the knowledge of known biosynthetic chemistry.

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Year:  2012        PMID： 22729219      PMCID： PMC3442147          DOI： 10.1039/c2np20023f

Source DB:  PubMed          Journal:  Nat Prod Rep        ISSN： 0265-0568            Impact factor:   13.423


  91 in total

Review 1.  Assembly-line enzymology for polyketide and nonribosomal Peptide antibiotics: logic, machinery, and mechanisms.

Authors:  Michael A Fischbach; Christopher T Walsh
Journal:  Chem Rev       Date:  2006-08       Impact factor: 60.622

2.  Impact of epimerization domains on the intermodular transfer of enzyme-bound intermediates in nonribosomal peptide synthesis.

Authors:  Daniel B Stein; Uwe Linne; Martin Hahn; Mohamed A Marahiel
Journal:  Chembiochem       Date:  2006-11       Impact factor: 3.164

3.  Biosynthesis of himastatin: assembly line and characterization of three cytochrome P450 enzymes involved in the post-tailoring oxidative steps.

Authors:  Junying Ma; Zhongwen Wang; Hongbo Huang; Minghe Luo; Dianguang Zuo; Bo Wang; Aijun Sun; Yi-Qiang Cheng; Changsheng Zhang; Jianhua Ju
Journal:  Angew Chem Int Ed Engl       Date:  2011-07-01       Impact factor: 15.336

4.  A four-enzyme pathway for 3,5-dihydroxy-4-methylanthranilic acid formation and incorporation into the antitumor antibiotic sibiromycin.

Authors:  Tobias W Giessen; Femke I Kraas; Mohamed A Marahiel
Journal:  Biochemistry       Date:  2011-06-03       Impact factor: 3.162

5.  Structural basis for phosphopantetheinyl carrier domain interactions in the terminal module of nonribosomal peptide synthetases.

Authors:  Ye Liu; Tengfei Zheng; Steven D Bruner
Journal:  Chem Biol       Date:  2011-11-23

6.  Chemoenzymatic synthesis of cryptophycin anticancer agents by an ester bond-forming non-ribosomal peptide synthetase module.

Authors:  Yousong Ding; Christopher M Rath; Kyle L Bolduc; Kristina Håkansson; David H Sherman
Journal:  J Am Chem Soc       Date:  2011-08-25       Impact factor: 15.419

7.  Phylogenomic analysis of non-ribosomal peptide synthetases in the genus Aspergillus.

Authors:  Robert A Cramer; Jason E Stajich; Yvonne Yamanaka; Fred S Dietrich; William J Steinbach; John R Perfect
Journal:  Gene       Date:  2006-07-21       Impact factor: 3.688

8.  Unraveling terminal C-domain-mediated condensation in fungal biosynthesis of imidazoindolone metabolites.

Authors:  Stuart W Haynes; Brian D Ames; Xue Gao; Yi Tang; Christopher T Walsh
Journal:  Biochemistry       Date:  2011-06-02       Impact factor: 3.162

9.  The identification of bacillaene, the product of the PksX megacomplex in Bacillus subtilis.

Authors:  Rebecca A Butcher; Frank C Schroeder; Michael A Fischbach; Paul D Straight; Roberto Kolter; Christopher T Walsh; Jon Clardy
Journal:  Proc Natl Acad Sci U S A       Date:  2007-01-18       Impact factor: 11.205

10.  Chain initiation in the leinamycin-producing hybrid nonribosomal peptide/polyketide synthetase from Streptomyces atroolivaceus S-140. Discrete, monofunctional adenylation enzyme and peptidyl carrier protein that directly load D-alanine.

Authors:  Gong-Li Tang; Yi-Qiang Cheng; Ben Shen
Journal:  J Biol Chem       Date:  2007-05-14       Impact factor: 5.157
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  22 in total

1.  Structure determination of the functional domain interaction of a chimeric nonribosomal peptide synthetase from a challenging crystal with noncrystallographic translational symmetry.

Authors:  Jesse A Sundlov; Andrew M Gulick
Journal:  Acta Crystallogr D Biol Crystallogr       Date:  2013-07-18

Review 2.  The Uncommon Enzymology of Cis-Acyltransferase Assembly Lines.

Authors:  Adrian T Keatinge-Clay
Journal:  Chem Rev       Date:  2017-04-10       Impact factor: 60.622

Review 3.  Refining and expanding nonribosomal peptide synthetase function and mechanism.

Authors:  Matt McErlean; Jonathan Overbay; Steven Van Lanen
Journal:  J Ind Microbiol Biotechnol       Date:  2019-01-23       Impact factor: 3.346

Review 4.  Engineering polyketide synthases and nonribosomal peptide synthetases.

Authors:  Gavin J Williams
Journal:  Curr Opin Struct Biol       Date:  2013-07-06       Impact factor: 6.809

5.  Biosynthetic multitasking facilitates thalassospiramide structural diversity in marine bacteria.

Authors:  Avena C Ross; Ying Xu; Liang Lu; Roland D Kersten; Zongze Shao; Abdulaziz M Al-Suwailem; Pieter C Dorrestein; Pei-Yuan Qian; Bradley S Moore
Journal:  J Am Chem Soc       Date:  2013-01-11       Impact factor: 15.419

6.  Discovery of the actinoplanic acid pathway in Streptomyces rapamycinicus reveals a genetically conserved synergism with rapamycin.

Authors:  Peter Mrak; Philipp Krastel; Petra Pivk Lukančič; Jianshi Tao; Dominik Pistorius; Charles M Moore
Journal:  J Biol Chem       Date:  2018-10-16       Impact factor: 5.157

Review 7.  Biotechnological production and application of epsilon-poly-L-lysine (ε-PL): biosynthesis and its metabolic regulation.

Authors:  Dahong Wang; Hemin Wang; Jinpeng Wu; Yuxin Hou; Jianrui Sun; Jiangfeng Yuan; Shaobin Gu
Journal:  World J Microbiol Biotechnol       Date:  2022-05-31       Impact factor: 3.312

8.  Analysis of the linker region joining the adenylation and carrier protein domains of the modular nonribosomal peptide synthetases.

Authors:  Bradley R Miller; Jesse A Sundlov; Eric J Drake; Thomas A Makin; Andrew M Gulick
Journal:  Proteins       Date:  2014-07-05

9.  Crystal Structure and Substrate Specificity of Human Thioesterase 2: INSIGHTS INTO THE MOLECULAR BASIS FOR THE MODULATION OF FATTY ACID SYNTHASE.

Authors:  Melissa K Ritchie; Lynnette C Johnson; Jill E Clodfelter; Charles W Pemble; Brian E Fulp; Cristina M Furdui; Steven J Kridel; W Todd Lowther
Journal:  J Biol Chem       Date:  2015-12-09       Impact factor: 5.157

Review 10.  Recent advances in combinatorial biosynthesis for drug discovery.

Authors:  Huihua Sun; Zihe Liu; Huimin Zhao; Ee Lui Ang
Journal:  Drug Des Devel Ther       Date:  2015-02-12       Impact factor: 4.162
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