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Literature DB >> 16895337

Assembly-line enzymology for polyketide and nonribosomal Peptide antibiotics: logic, machinery, and mechanisms.

Michael A Fischbach¹, Christopher T Walsh.

Abstract

Entities: Chemical

Mesh：

Substances：

Year: 2006 PMID： 16895337 DOI： 10.1021/cr0503097

Source DB: PubMed Journal: Chem Rev ISSN： 0009-2665 Impact factor: 60.622

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467 in total

1. Synergistic allelochemicals from a freshwater cyanobacterium.

Authors: Pedro N Leão; Alban R Pereira; Wei-Ting Liu; Julio Ng; Pavel A Pevzner; Pieter C Dorrestein; Gabriele M König; Vitor M Vasconcelos; William H Gerwick
Journal: Proc Natl Acad Sci U S A Date: 2010-06-07 Impact factor: 11.205

2. Microdiversity and evidence for high dispersal rates in the marine actinomycete 'Salinispora pacifica'.

Authors: Kelle C Freel; Anna Edlund; Paul R Jensen
Journal: Environ Microbiol Date: 2011-11-28 Impact factor: 5.491

3. Credneramides A and B: neuromodulatory phenethylamine and isopentylamine derivatives of a vinyl chloride-containing fatty acid from cf. Trichodesmium sp. nov.

Authors: Karla L Malloy; Takashi L Suyama; Niclas Engene; Hosana Debonsi; Zhengyu Cao; Teatulohi Matainaho; Carmenza Spadafora; Thomas F Murray; William H Gerwick
Journal: J Nat Prod Date: 2011-12-12 Impact factor: 4.050

Assembly-line enzymology for polyketide and nonribosomal Peptide antibiotics: logic, machinery, and mechanisms.

1. Synergistic allelochemicals from a freshwater cyanobacterium.

2. Microdiversity and evidence for high dispersal rates in the marine actinomycete 'Salinispora pacifica'.

3. Credneramides A and B: neuromodulatory phenethylamine and isopentylamine derivatives of a vinyl chloride-containing fatty acid from cf. Trichodesmium sp. nov.

4. Full-length RecE enhances linear-linear homologous recombination and facilitates direct cloning for bioprospecting.

5. Horizontal gene transfer and gene conversion drive evolution of modular polyketide synthases.

6. Reconstruction of the saframycin core scaffold defines dual Pictet-Spengler mechanisms.

7. Use of the dehydrophos biosynthetic enzymes to prepare antimicrobial analogs of alaphosphin.

8. Massetolide A biosynthesis in Pseudomonas fluorescens.

9. Involvement of both PKS and NRPS in antibacterial activity in Lysobacter enzymogenes OH11.

Review 10. Diiron monooxygenases in natural product biosynthesis.