Literature DB >> 227059

A sign inversion mechanism for enzymatic supercoiling of DNA.

P O Brown, N R Cozzarelli.   

Abstract

Both the introduction and the removal of supertwists by DNA gyrase change the linking number of DNA in steps of two. This surprising finding provides strong evidence that gyrase acts by a mechanism, called sign inversion, whereby a positive supercoil is directly inverted into a negative one via a transient double-strand break.

Entities:  

Mesh：

Substances：

Year:  1979        PMID： 227059     DOI： 10.1126/science.227059

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  87 in total

Review 1.  Topological challenges to DNA replication: conformations at the fork.

Authors:  L Postow; N J Crisona; B J Peter; C D Hardy; N R Cozzarelli
Journal:  Proc Natl Acad Sci U S A       Date:  2001-07-17       Impact factor: 11.205

2.  Alteration of Escherichia coli topoisomerase IV to novobiocin resistance.

Authors:  Christine D Hardy; Nicholas R Cozzarelli
Journal:  Antimicrob Agents Chemother       Date:  2003-03       Impact factor: 5.191

3.  The mechanism of type IA topoisomerases.

Authors:  N H Dekker; V V Rybenkov; M Duguet; N J Crisona; N R Cozzarelli; D Bensimon; V Croquette
Journal:  Proc Natl Acad Sci U S A       Date:  2002-08-07       Impact factor: 11.205

4.  The C-terminal domain of DNA gyrase A adopts a DNA-bending beta-pinwheel fold.

Authors:  Kevin D Corbett; Ryan K Shultzaberger; James M Berger
Journal:  Proc Natl Acad Sci U S A       Date:  2004-05-03       Impact factor: 11.205

5.  Computational analysis of DNA gyrase action.

Authors:  Alexander Vologodskii
Journal:  Biophys J       Date:  2004-08-31       Impact factor: 4.033

Review 6.  Disentangling DNA during replication: a tale of two strands.

Authors:  Christine D Hardy; Nancy J Crisona; Michael D Stone; Nicholas R Cozzarelli
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2004-01-29       Impact factor: 6.237

Review 7.  Single-molecule measurements of DNA topology and topoisomerases.

Authors:  Keir C Neuman
Journal:  J Biol Chem       Date:  2010-04-09       Impact factor: 5.157

Review 8.  Cellular strategies for regulating DNA supercoiling: a single-molecule perspective.

Authors:  Daniel A Koster; Aurélien Crut; Stewart Shuman; Mary-Ann Bjornsti; Nynke H Dekker
Journal:  Cell       Date:  2010-08-20       Impact factor: 41.582

9.  Mechanochemical analysis of DNA gyrase using rotor bead tracking.

Authors:  Jeff Gore; Zev Bryant; Michael D Stone; Marcelo Nöllmann; Nicholas R Cozzarelli; Carlos Bustamante
Journal:  Nature       Date:  2006-01-05       Impact factor: 49.962

10.  Evidence for a nucleotide-dependent topoisomerase activity from yeast mitochondria.

Authors:  U R Ezekiel; E M Towler; J W Wallis; H P Zassenhaus
Journal:  Curr Genet       Date:  1994-12       Impact factor: 3.886
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.