| Literature DB >> 22455 |
F Awouters, C J Niemegeers, J Van den Berk, J M Van Neuten, F M Lenaerts, M Borgers, K H Schellekens, A Broeckaert, J De Cree, P A Janssen.
Abstract
Oxatomide is a new potent inhibitor of anaphylactic and allergic reactions. After oral administration, the compound both inhibits the release of endogenous histamine and prevents the effects of exogensous histamine, at comparable doses. The combination of these effects appears to be the basis of the effectiveness of oxatomide in allergic reactions and may lead to clinical application different from classical antihistaminics and from cromoglycate.Entities:
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Year: 1977 PMID： 22455 DOI： 10.1007/BF01934056
Source DB: PubMed Journal: Experientia ISSN： 0014-4754