Literature DB >> 22360686

Antimicrobial metabolites from the Paracel Islands sponge Agelas mauritiana.

Fan Yang1, Mark T Hamann, Yike Zou, Ming-Yu Zhang, Xiao-Bin Gong, Jian-Ru Xiao, Wan-Sheng Chen, Hou-Wen Lin.   

Abstract

Four new alkaloids, (-)-8'-oxo-agelasine D (2), ageloxime B (3), (+)-2-oxo-agelasidine C (4), and 4-bromo-N-(butoxymethyl)-1H-pyrrole-2-carboxamide (5), and the known compound (-)-ageloxime D (1) were isolated from the marine sponge Agelas mauritiana. Their chemical structures were established on the basis of spectroscopic analysis. Compounds 1 and 3 both showed antifungal activity against Cryptococcus neoformans and antileishmanial activity against Leishmania donovani in vitro. Compound 3 also exhibited antibacterial activity against Staphylococcus aureus and methicillin-resistant S. aureusin vitro.
© 2012 American Chemical Society and American Society of Pharmacognosy

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Year:  2012        PMID： 22360686      PMCID： PMC4883697          DOI： 10.1021/np2009016

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  9 in total

1.  Novel bioactive bromopyrrole alkaloids from the Mediterranean sponge Axinella verrucosa.

Authors:  Anna Aiello; Monica D'Esposito; Ernesto Fattorusso; Marialuisa Menna; Werner E G Müller; Sanja Perović-Ottstadt; Heinz C Schröder
Journal:  Bioorg Med Chem       Date:  2005-09-16       Impact factor: 3.641

2.  Agelasine G, a new antileukemic alkaloid from the Okinawan marine sponge Agelas sp.

Authors:  K Ishida; M Ishibashi; H Shigemori; T Sasaki; J Kobayashi
Journal:  Chem Pharm Bull (Tokyo)       Date:  1992-03       Impact factor: 1.645

3.  Agelasines J, K, and L from the Solomon Islands Marine Sponge Agelas cf. mauritiana.

Authors:  Jérôme Appenzeller; Ghezala Mihci; Marie-Thérèse Martin; Jean-François Gallard; Jean-Louis Menou; Nicole Boury-Esnault; John Hooper; Sylvain Petek; Severine Chevalley; Alexis Valentin; Anne Zaparucha; Ali Al-Mourabit; Cécile Debitus
Journal:  J Nat Prod       Date:  2008-06-24       Impact factor: 4.050

4.  (-)-agelasidine C and (-)-agelasidine D, two new hypotaurocyamine diterpenoids from the Caribbean sea sponge Agelas clathrodes.

Authors:  J J Morales; A D Rodríguez
Journal:  J Nat Prod       Date:  1992-03       Impact factor: 4.050

5.  Rapid, low-technology MIC determination with clinical Mycobacterium tuberculosis isolates by using the microplate Alamar Blue assay.

Authors:  S G Franzblau; R S Witzig; J C McLaughlin; P Torres; G Madico; A Hernandez; M T Degnan; M B Cook; V K Quenzer; R M Ferguson; R H Gilman
Journal:  J Clin Microbiol       Date:  1998-02       Impact factor: 5.948

6.  (+)-agelasine D: improved synthesis and evaluation of antibacterial and cytotoxic activities.

Authors:  Anders Vik; Erik Hedner; Colin Charnock; Orjan Samuelsen; Rolf Larsson; Lise-Lotte Gundersen; Lars Bohlin
Journal:  J Nat Prod       Date:  2006-03       Impact factor: 4.050

7.  A simple colorimetric method to screen drug cytotoxicity against Leishmania using the dye Alamar Blue.

Authors:  J Mikus; D Steverding
Journal:  Parasitol Int       Date:  2000-01       Impact factor: 2.230

8.  Nagelamides A-H, new dimeric bromopyrrole alkaloids from marine sponge Agelas species.

Authors:  Tadashi Endo; Masashi Tsuda; Tadashi Okada; Shinya Mitsuhashi; Hiroshi Shima; Kunimi Kikuchi; Yuzuru Mikami; Jane Fromont; Jun'ichi Kobayashi
Journal:  J Nat Prod       Date:  2004-08       Impact factor: 4.050

9.  From anti-fouling to biofilm inhibition: new cytotoxic secondary metabolites from two Indonesian Agelas sponges.

Authors:  Triana Hertiani; RuAngelie Edrada-Ebel; Sofia Ortlepp; Rob W M van Soest; Nicole J de Voogd; Victor Wray; Ute Hentschel; Svetlana Kozytska; Werner E G Müller; Peter Proksch
Journal:  Bioorg Med Chem       Date:  2010-01-12       Impact factor: 3.641
  9 in total
  11 in total

Review 1.  Antifungal and antiviral products of marine organisms.

Authors:  Randy Chi Fai Cheung; Jack Ho Wong; Wen Liang Pan; Yau Sang Chan; Cui Ming Yin; Xiu Li Dan; He Xiang Wang; Evandro Fei Fang; Sze Kwan Lam; Patrick Hung Kui Ngai; Li Xin Xia; Fang Liu; Xiu Yun Ye; Guo Qing Zhang; Qing Hong Liu; Ou Sha; Peng Lin; Chan Ki; Adnan A Bekhit; Alaa El-Din Bekhit; David Chi Cheong Wan; Xiu Juan Ye; Jiang Xia; Tzi Bun Ng
Journal:  Appl Microbiol Biotechnol       Date:  2014-02-23       Impact factor: 4.813

2.  Antifungal Diterpene Alkaloids from the Caribbean Sponge Agelas citrina: Unified Configurational Assignments of Agelasidines and Agelasines.

Authors:  E Paige Stout; Lily C Yu; Tadeusz F Molinski
Journal:  European J Org Chem       Date:  2012-09

Review 3.  Marine Pyrrole Alkaloids.

Authors:  Kevin Seipp; Leander Geske; Till Opatz
Journal:  Mar Drugs       Date:  2021-09-10       Impact factor: 5.118

Review 4.  Marine Alkylpurines: A Promising Group of Bioactive Marine Natural Products.

Authors:  Pablo A García; Elena Valles; David Díez; María-Ángeles Castro
Journal:  Mar Drugs       Date:  2018-01-01       Impact factor: 5.118

Review 5.  Current Status and Future Prospects of Marine Natural Products (MNPs) as Antimicrobials.

Authors:  Alka Choudhary; Lynn M Naughton; Itxaso Montánchez; Alan D W Dobson; Dilip K Rai
Journal:  Mar Drugs       Date:  2017-08-28       Impact factor: 5.118

Review 6.  Marine Pharmacology in 2012-2013: Marine Compounds with Antibacterial, Antidiabetic, Antifungal, Anti-Inflammatory, Antiprotozoal, Antituberculosis, and Antiviral Activities; Affecting the Immune and Nervous Systems, and Other Miscellaneous Mechanisms of Action.

Authors:  Alejandro M S Mayer; Abimael D Rodríguez; Orazio Taglialatela-Scafati; Nobuhiro Fusetani
Journal:  Mar Drugs       Date:  2017-08-29       Impact factor: 5.118

Review 7.  A Decade of Antifungal Leads from Natural Products: 2010-2019.

Authors:  Mohammed Aldholmi; Pascal Marchand; Isabelle Ourliac-Garnier; Patrice Le Pape; A Ganesan
Journal:  Pharmaceuticals (Basel)       Date:  2019-12-12

8.  Agelasine Diterpenoids and Cbl-b Inhibitory Ageliferins from the Coralline Demosponge Astrosclera willeyana.

Authors:  Wei Jiang; Dongdong Wang; Brice A P Wilson; Unwoo Kang; Heidi R Bokesch; Emily A Smith; Antony Wamiru; Ekaterina I Goncharova; Donna Voeller; Stanley Lipkowitz; Barry R O'Keefe; Kirk R Gustafson
Journal:  Mar Drugs       Date:  2021-06-24       Impact factor: 5.118

9.  ArCH(OMe)₂--a Pt(IV)-catalyst originator for diverse annulation catalysis.

Authors:  Subhadeep Ghosh; Saikat Khamarui; Krishnanka S Gayen; Dilip K Maiti
Journal:  Sci Rep       Date:  2013-10-18       Impact factor: 4.379

Review 10.  Bioactive Secondary Metabolites from the Marine Sponge Genus Agelas.

Authors:  Huawei Zhang; Menglian Dong; Jianwei Chen; Hong Wang; Karen Tenney; Phillip Crews
Journal:  Mar Drugs       Date:  2017-11-08       Impact factor: 5.118
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