| Literature DB >> 22094950 |
Tobias Warnecke1, Laurence D Hurst.
Abstract
Why are short introns rarely a multiple of three nucleotides long? Why do essential genes cluster? Why are genes in operons often lined up in the order in which they are needed in the encoded pathway? In this Opinion article, we argue that these and many other - ostensibly disparate - observations are all pieces of an emerging picture in which multiple aspects of gene anatomy and genome architecture have evolved in response to error-prone gene expression.Mesh：
Year: 2011 PMID： 22094950 DOI： 10.1038/nrg3092
Source DB: PubMed Journal: Nat Rev Genet ISSN： 1471-0056 Impact factor: 53.242