PURPOSE: To evaluate the relationship between "Look-Locker" (LL) and modified Look-Locker Inversion recovery (MOLLI) approaches for T1 mapping of the myocardium. MATERIALS AND METHODS: A total of 168 myocardial T1 maps using MOLLI and 165 maps using LL were obtained in human subjects at 1.5 Tesla. The T1 values of the myocardium were calculated before and at five time points after gadolinium administration. All time and heart rate normalizations were done. The T1 values obtained were compared to determine the absolute and bias agreement. RESULTS: The precontrast global T1 values were similar when measured by the LL and by MOLLI technique (mean, 1004.9 ms ± 120.3 versus 1034.1 ms ± 53.1, respectively, P = 0.26). Postcontrast myocardial T1 time from LL was significantly longer than MOLLI from 5 to 25 min (mean difference, LL - MOLLI was +61.8 ± 46.4 ms, P < 0.001). No significant differences in T1 values were noted between long and short axis measurements for either MOLLI or LL. CONCLUSION: Postcontrast LL and MOLLI showed very good agreement, although LL values are higher than MOLLI. Precontrast T1 values showed good agreement, however LL has greater limits of agreement. Short and long axis planes can reliably assess T1 values.
PURPOSE: To evaluate the relationship between "Look-Locker" (LL) and modified Look-Locker Inversion recovery (MOLLI) approaches for T1 mapping of the myocardium. MATERIALS AND METHODS: A total of 168 myocardial T1 maps using MOLLI and 165 maps using LL were obtained in human subjects at 1.5 Tesla. The T1 values of the myocardium were calculated before and at five time points after gadolinium administration. All time and heart rate normalizations were done. The T1 values obtained were compared to determine the absolute and bias agreement. RESULTS: The precontrast global T1 values were similar when measured by the LL and by MOLLI technique (mean, 1004.9 ms ± 120.3 versus 1034.1 ms ± 53.1, respectively, P = 0.26). Postcontrast myocardial T1 time from LL was significantly longer than MOLLI from 5 to 25 min (mean difference, LL - MOLLI was +61.8 ± 46.4 ms, P < 0.001). No significant differences in T1 values were noted between long and short axis measurements for either MOLLI or LL. CONCLUSION: Postcontrast LL and MOLLI showed very good agreement, although LL values are higher than MOLLI. Precontrast T1 values showed good agreement, however LL has greater limits of agreement. Short and long axis planes can reliably assess T1 values.
Authors: Daniel R Messroghli; Andre Rudolph; Hassan Abdel-Aty; Ralf Wassmuth; Titus Kühne; Rainer Dietz; Jeanette Schulz-Menger Journal: BMC Med Imaging Date: 2010-07-30 Impact factor: 1.930
Authors: Andrew S Flett; Martin P Hayward; Michael T Ashworth; Michael S Hansen; Andrew M Taylor; Perry M Elliott; Christopher McGregor; James C Moon Journal: Circulation Date: 2010-06-28 Impact factor: 29.690
Authors: Evrim B Turkbey; Robyn L McClelland; Richard A Kronmal; Gregory L Burke; Diane E Bild; Russell P Tracy; Andrew E Arai; João A C Lima; David A Bluemke Journal: JACC Cardiovasc Imaging Date: 2010-03
Authors: Leah Iles; Heinz Pfluger; Arintaya Phrommintikul; Joshi Cherayath; Pelin Aksit; Sandeep N Gupta; David M Kaye; Andrew J Taylor Journal: J Am Coll Cardiol Date: 2008-11-04 Impact factor: 24.094
Authors: Daniel R Messroghli; Kevin Walters; Sven Plein; Patrick Sparrow; Matthias G Friedrich; John P Ridgway; Mohan U Sivananthan Journal: Magn Reson Med Date: 2007-07 Impact factor: 3.737
Authors: Sebastian Gassenmaier; Rob J van der Geest; U Joseph Schoepf; Pal Suranyi; Wolfgang G Rehwald; Carlo N De Cecco; Domenico Mastrodicasa; Moritz H Albrecht; Domenico De Santis; Virginia W Lesslie; Balazs Ruzsics; Akos Varga-Szemes Journal: Int J Cardiovasc Imaging Date: 2018-01-05 Impact factor: 2.357
Authors: Christopher T Sibley; Radwa A Noureldin; Neville Gai; Marcelo Souto Nacif; Songtao Liu; Evrim B Turkbey; James O Mudd; Rob J van der Geest; João A C Lima; Marc K Halushka; David A Bluemke Journal: Radiology Date: 2012-10-22 Impact factor: 11.105
Authors: William S Bradham; Susan P Bell; Douglas W Adkisson; Holly M Smith; Frank E Harrell; Mark A Lawson; Henry Ooi; Douglas B Sawyer; Marvin W Kronenberg Journal: J Card Fail Date: 2016-12-08 Impact factor: 5.712