Literature DB >> 21926580

The rising incidence of intentional ingestion of ethanol-containing hand sanitizers.

Nicole J Gormley1, Alvin C Bronstein, Joseph J Rasimas, Maryland Pao, Angela T Wratney, Junfeng Sun, Howard A Austin, Anthony F Suffredini.   

Abstract

OBJECTIVE: To describe a case of intentional ingestion of hand sanitizer in our hospital and to review published cases and those reported to the American Association of Poison Control Centers' National Poison Data System.
DESIGN: A case report, a literature review of published cases, and a query of the National Poison Data System.
SETTING: Medical intensive care unit. PATIENT: Seventeen-yr-old male 37-kg with an intentional ingestion of a hand sanitizer product into his gastrostomy tube.
INTERVENTIONS: Intubation, ventilation, and hemodialysis.
MEASUREMENTS AND MAIN RESULTS: Incidence and outcome of reported cases of unintentional and intentional ethanol containing-hand sanitizer ingestion in the United States from 2005 through 2009. A literature search found 14 detailed case reports of intentional alcohol-based hand sanitizer ingestions with one death. From 2005 to 2009, the National Poison Data System received reports of 68,712 exposures to 96 ethanol-based hand sanitizers. The number of new cases increased by an average of 1,894 (95% confidence interval [CI] 1266-2521) cases per year (p =.002). In 2005, the rate of exposures, per year, per million U.S. residents was 33.7 (95% CI 28.4-39.1); from 2005 to 2009, this rate increased on average by 5.87 per year (95% CI 3.70-8.04; p = .003). In 2005, the rate of intentional exposures, per year, per million U.S. residents, was 0.68 (95% CI 0.17-1.20); from 2005 to 2009, this rate increased on average by 0.32 per year (95% CI 0.11-0.53; p = .02).
CONCLUSIONS: The number of new cases per year of intentional hand sanitizer ingestion significantly increased during this 5-yr period. Although the majority of cases of hand sanitizer ingestion have a favorable outcome, 288 moderate and 12 major medical outcomes were reported in this National Poison Data System cohort. Increased awareness of the risks associated with intentional ingestion is warranted, particularly among healthcare providers caring for persons with a history of substance abuse, risk-taking behavior, or suicidal ideation.

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Year:  2012        PMID: 21926580      PMCID: PMC3408316          DOI: 10.1097/CCM.0b013e31822f09c0

Source DB:  PubMed          Journal:  Crit Care Med        ISSN: 0090-3493            Impact factor:   7.598


  21 in total

1.  Intoxication of a hospitalized patient with an isopropanol-based hand sanitizer.

Authors:  Ashkan Emadi; LeAnn Coberly
Journal:  N Engl J Med       Date:  2007-02-01       Impact factor: 91.245

2.  Intoxication of a prison inmate with an ethyl alcohol-based hand sanitizer.

Authors:  Suzanne Doyon; Christopher Welsh
Journal:  N Engl J Med       Date:  2007-02-01       Impact factor: 91.245

3.  A voluntary ingestion of alcohol-based hand rub.

Authors:  M-P Tavolacci; H Marini; S Vanheste; V Merle; A-M Coulon; G Micaud; P Czernichow
Journal:  J Hosp Infect       Date:  2007-03-12       Impact factor: 3.926

Review 4.  Alcohol hand rubs: hygiene and hazard.

Authors:  John R H Archer; David M Wood; Zoe Tizzard; Alison L Jones; Paul I Dargan
Journal:  BMJ       Date:  2007-12-01

5.  Hemodialysis as a treatment of severe ethanol poisoning.

Authors:  W A Atassi; A A Noghnogh; R Hariman; S Jayanthi; S F Cheung; C M Kjellstrand; T S Ing
Journal:  Int J Artif Organs       Date:  1999-01       Impact factor: 1.595

6.  Severe ethanol poisoning: a case report and brief review.

Authors:  M Sanap; M J Chapman
Journal:  Crit Care Resusc       Date:  2003-06       Impact factor: 2.159

7.  2009 Annual Report of the American Association of Poison Control Centers' National Poison Data System (NPDS): 27th Annual Report.

Authors:  Alvin C Bronstein; Daniel A Spyker; Louis R Cantilena; Jody L Green; Barry H Rumack; Sandra L Giffin
Journal:  Clin Toxicol (Phila)       Date:  2010-12       Impact factor: 4.467

8.  Severe alcohol hand rub overdose inducing coma, watch after H1N1 pandemic.

Authors:  Matthieu Henry-Lagarrigue; Magali Charbonnier; Fabrice Bruneel; Stéphane Legriel; Gilles Troche; Hager Ben Mokhtar; Aihem Yehia; Pierre Guezennec; Jacques Merrer; Catherine Palette; Jean-Pierre Bedos
Journal:  Neurocrit Care       Date:  2010-06       Impact factor: 3.210

9.  Poisoning with 1-propanol and 2-propanol.

Authors:  M Vujasinovic; M Kocar; K Kramer; M Bunc; M Brvar
Journal:  Hum Exp Toxicol       Date:  2007-12       Impact factor: 2.903

10.  A case of mixed intoxication with isopropyl alcohol and propanol-1 after ingestion of a topical antiseptic solution.

Authors:  Benoit Blanchet; Antoine Charachon; Stéphanie Lukat; Estelle Huet; Anne Hulin; Alain Astier
Journal:  Clin Toxicol (Phila)       Date:  2007-09       Impact factor: 4.467

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  17 in total

1.  Renal replacement therapy in the management of intoxications in children: recommendations from the Pediatric Continuous Renal Replacement Therapy (PCRRT) workgroup.

Authors:  Rupesh Raina; Manpreet K Grewal; Martha Blackford; Jordan M Symons; Michael J G Somers; Christoph Licht; Rajit K Basu; Sidharth Kumar Sethi; Deepa Chand; Gaurav Kapur; Mignon McCulloch; Arvind Bagga; Vinod Krishnappa; Hui-Kim Yap; Marcelo de Sousa Tavares; Timothy E Bunchman; Michelle Bestic; Bradley A Warady; Maria Díaz-González de Ferris
Journal:  Pediatr Nephrol       Date:  2019-08-24       Impact factor: 3.714

Review 2.  Toxic alcohol diagnosis and management: an emergency medicine review.

Authors:  Patrick Chow Yuen Ng; Brit J Long; William Tyler Davis; Daniel J Sessions; Alex Koyfman
Journal:  Intern Emerg Med       Date:  2018-02-09       Impact factor: 3.397

3.  Recurrent lactic acidosis secondary to hand sanitizer ingestion.

Authors:  M E Wilson; P K Guru; J G Park
Journal:  Indian J Nephrol       Date:  2015 Jan-Feb

4.  Reported Adverse Health Effects in Children from Ingestion of Alcohol-Based Hand Sanitizers - United States, 2011-2014.

Authors:  Cynthia Santos; Stephanie Kieszak; Alice Wang; Royal Law; Joshua Schier; Amy Wolkin
Journal:  MMWR Morb Mortal Wkly Rep       Date:  2017-03-03       Impact factor: 17.586

5.  Tainted Hand Sanitizer Leads to Outbreak of Methanol Toxicity During SARS-CoV-2 Pandemic.

Authors:  Luke Welle; Amanda Medoro; Brandon Warrick
Journal:  Ann Emerg Med       Date:  2020-07-08       Impact factor: 5.721

6.  Lack of Handwashing Access: A Widespread Deficiency in the Age of COVID-19.

Authors:  Charles W Schmidt
Journal:  Environ Health Perspect       Date:  2020-06-29       Impact factor: 9.031

7.  A Social Media-Based Acute Alcohol Consumption Behavior (NekNomination): Case Series in Italian Emergency Departments.

Authors:  Stefania Barbieri; Paolo Feltracco; Vittorio Lucchetta; Rosa Maria Gaudio; Alberto Tredese; Mauro Bergamini; Gianna Vettore; Vincenzo Pietrantonio; Francesco Maria Avato; Daniele Donato; Deris Gianni Boemo; Maria Vittoria Nesoti; Rossella Snenghi
Journal:  Interact J Med Res       Date:  2018-01-31

Review 8.  COVID-19 and frequent use of hand sanitizers; human health and environmental hazards by exposure pathways.

Authors:  Adeel Mahmood; Maryam Eqan; Saher Pervez; Huda Ahmed Alghamdi; Amtul Bari Tabinda; Abdullah Yasar; Kathirvel Brindhadevi; Arivalagan Pugazhendhi
Journal:  Sci Total Environ       Date:  2020-06-27       Impact factor: 10.753

9.  Gastrointestinal effects of an attempt to avoid contracting COVID-19 by 'disinfection'.

Authors:  Lukas Binder; Christoph Högenauer; Cord Langner
Journal:  Histopathology       Date:  2020-06-29       Impact factor: 7.778

10.  Morbidity in the COVID-19 era: Ethanol intoxication secondary to hand sanitiser ingestion.

Authors:  Sandra Hanna; Karen Zwi; Dimitra Tzioumi
Journal:  J Paediatr Child Health       Date:  2020-08-05       Impact factor: 1.929

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