Literature DB >> 29427181

Toxic alcohol diagnosis and management: an emergency medicine review.

Patrick Chow Yuen Ng1, Brit J Long1, William Tyler Davis2, Daniel J Sessions1, Alex Koyfman3.   

Abstract

Toxic alcohols are a group of substances containing a hydroxyl group not meant to be ingested. They are the cause of a significant number of accidental and non-accidental exposures. Toxic alcohol poisoning can be associated with a significant degree of morbidity and mortality if not promptly recognized and treated. This review describes the clinical presentation and an approach to the recognition and management for toxic alcohol poisoning. Toxic alcohols classically refer to a group of alcohols not meant for ingestion. Methanol, ethylene glycol, and isopropyl alcohol are readily available in common hardware and household materials. Toxic alcohols are ingested for a variety of reasons including accidental exposures, intentional inebriation, homicide and suicide. The patient with an altered mental status or concerning history warrants consideration of this potentially deadly ingestion. Treatment considerations include alcohol dehydrogenase blockade and hemodialysis. Toxic alcohol poisoning can be an elusive diagnosis. This review evaluates toxic alcohol poisoning signs and symptoms and an approach to diagnosis and management.

Entities:  

Keywords:  Alcohol; Ethylene glycol; Fomepizole; Hemodialysis; Isopropyl alcohol; Methanol; Toxic alcohol

Mesh:

Substances:

Year:  2018        PMID: 29427181     DOI: 10.1007/s11739-018-1799-9

Source DB:  PubMed          Journal:  Intern Emerg Med        ISSN: 1828-0447            Impact factor:   3.397


  63 in total

Review 1.  Current management of ethylene glycol poisoning.

Authors:  J Brent
Journal:  Drugs       Date:  2001       Impact factor: 9.546

Review 2.  Ethylene glycol or methanol intoxication: which antidote should be used, fomepizole or ethanol?

Authors:  S J Rietjens; D W de Lange; J Meulenbelt
Journal:  Neth J Med       Date:  2014-02       Impact factor: 1.422

3.  Hydrocarbon Enema: An Unusual Cause of Chemical Burn.

Authors:  Justin Mygatt; Mustafa Amani; Patrick Ng; Brian Benson; Jeremy Pamplin; Leopoldo Cancio
Journal:  J Burn Care Res       Date:  2017 Sep/Oct       Impact factor: 1.845

4.  A Prospective Observation Study of Medical Toxicology Consultation in a U.S. Combat Theater.

Authors:  Joseph K Maddry; Patrick C Ng; Daniel Sessions; Vikhyat S Bebarta
Journal:  Mil Med       Date:  2016-11       Impact factor: 1.437

5.  Efficiency of acidemia correction on intermittent versus continuous hemodialysis in acute methanol poisoning.

Authors:  Sergey Zakharov; Daniela Pelclova; Tomas Navratil; Jaromir Belacek; Jiri Latta; Michal Pisar; Jan Rulisek; Jiri Leps; Pavel Zidek; Cyril Kucera; Robert Bocek; Miroslav Mazur; Zdenek Belik; Josef Chalupa; Viktor Talafa; Kamil Kodras; Daniel Nalos; Ctirad Sedlak; Michal Senkyrik; Jan Smid; Tomas Salek; Darren M Roberts; Knut Erik Hovda
Journal:  Clin Toxicol (Phila)       Date:  2016-11-07       Impact factor: 4.467

6.  The role of calcium oxalate crystal deposition in cerebral vessels during ethylene glycol poisoning.

Authors:  K Froberg; R P Dorion; K E McMartin
Journal:  Clin Toxicol (Phila)       Date:  2006       Impact factor: 4.467

Review 7.  Antidotes for poisoning by alcohols that form toxic metabolites.

Authors:  Kenneth McMartin; Dag Jacobsen; Knut Erik Hovda
Journal:  Br J Clin Pharmacol       Date:  2016-01-04       Impact factor: 4.335

8.  The impact of community-acquired pneumonia on the health-related quality-of-life in elderly.

Authors:  Marie-Josée J Mangen; Susanne M Huijts; Marc J M Bonten; G Ardine de Wit
Journal:  BMC Infect Dis       Date:  2017-03-14       Impact factor: 3.090

9.  Efficacy and Safety of Thrombolytic Therapy in Acute Submassive Pulmonary Embolism: Follow-Up Study.

Authors:  Santosh Kumar Sinha; Mohit Sachan; Amit Goel; Karandeep Singh; Vikas Mishra; Mukesh Jitendra Jha; Ashutosh Kumar; Nasar Abdali; Mohammad Asif; Mahamdula Razi; Umeshwar Pandey; Ramesh Thakur; Chandra Mohan Varma; Vinay Krishna
Journal:  J Clin Med Res       Date:  2016-12-31

10.  Methanol poisoning and long term sequelae - a six years follow-up after a large methanol outbreak.

Authors:  Raido Paasma; Knut Erik Hovda; Dag Jacobsen
Journal:  BMC Clin Pharmacol       Date:  2009-03-27
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  6 in total

1.  Toxic alcohol diagnosis and management: an emergency medicine review-comment.

Authors:  Samaneh Nakhaee; Kobra Naseri; Omid Mehrpour
Journal:  Intern Emerg Med       Date:  2019-01-01       Impact factor: 3.397

2.  Toxic alcohol poisoning characteristics and treatments from 2000 to 2017 at a United States regional poison center.

Authors:  Christopher Hoyte; Jonathan Schimmel; Ali Hadianfar; Shireen Banerji; Samaneh Nakhaee; Omid Mehrpour
Journal:  Daru       Date:  2021-10-28       Impact factor: 3.117

3.  Diabetic ketoacidosis as a complication of methanol poisoning; a case report.

Authors:  Azam Erfanifar; Mahsa Mahjani; Sara Salimpour; Nasim Zamani; Hossein Hassanian-Moghaddam
Journal:  BMC Endocr Disord       Date:  2022-06-02       Impact factor: 3.263

4.  Leveraging genetic data to investigate molecular targets and drug repurposing candidates for treating alcohol use disorder and hepatotoxicity.

Authors:  Joshua C Gray; Mikela Murphy; Lorenzo Leggio
Journal:  Drug Alcohol Depend       Date:  2020-07-02       Impact factor: 4.492

5.  Potential methanol toxicity and the importance of using a standardised alcohol-based hand rub formulation in the era of COVID-19.

Authors:  K Dear; L Grayson; R Nixon
Journal:  Antimicrob Resist Infect Control       Date:  2020-08-08       Impact factor: 4.887

6.  Outcomes after toxic alcohol poisoning: a systematic review protocol.

Authors:  Carol Wang; Daniel Samaha; Swapnil Hiremath; Lindsey Sikora; Manish M Sood; Salmaan Kanji; Edward G Clark
Journal:  Syst Rev       Date:  2018-12-28
  6 in total

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