Literature DB >> 17849246

A case of mixed intoxication with isopropyl alcohol and propanol-1 after ingestion of a topical antiseptic solution.

Benoit Blanchet1, Antoine Charachon, Stéphanie Lukat, Estelle Huet, Anne Hulin, Alain Astier.   

Abstract

We report a mixed intoxication with isopropyl alcohol and propanol-1 in a hospitalized patient who ingested, on two separate days, two 100 ml bottles of a topical antiseptic solution containing isopropyl alcohol and propanol-1. Eight hours after the second ingestion, plasma concentrations of isopropanol, propanol-1 and acetone were 37 mg/dL, <10 mg/dL, and 227 mg/dl, respectively. Despite a lack of severe toxicity, 4-methylpyrazole (fomepizole) was initiated. This case points out the need to limit access to alcohol-containing antiseptic solutions on wards where alcoholic and psychotic patients are hospitalized.

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Year:  2007        PMID: 17849246     DOI: 10.1080/15563650701517285

Source DB:  PubMed          Journal:  Clin Toxicol (Phila)        ISSN: 1556-3650            Impact factor:   4.467


  4 in total

1.  Poisoning with Ethanol and 2-Propanol-Based Hand Rubs: Give Caesar What Belongs to Caesar!

Authors:  Bruno Mégarbane; Antoine Villa
Journal:  Neurocrit Care       Date:  2019-02       Impact factor: 3.210

2.  An unnatural death by propan-1-ol and propan-2-ol.

Authors:  Gisela Skopp; Isabelle Gutmann; Clara-Sophie Schwarz; Georg Schmitt
Journal:  Int J Legal Med       Date:  2015-12-28       Impact factor: 2.686

Review 3.  The rising incidence of intentional ingestion of ethanol-containing hand sanitizers.

Authors:  Nicole J Gormley; Alvin C Bronstein; Joseph J Rasimas; Maryland Pao; Angela T Wratney; Junfeng Sun; Howard A Austin; Anthony F Suffredini
Journal:  Crit Care Med       Date:  2012-01       Impact factor: 7.598

4.  A Case of Unintentional Isopropanol Poisoning via Transdermal Absorption Delayed by Weekly Hemodialysis.

Authors:  Andrew R Chavez; Michael Sweeney; Peter Akpunonu
Journal:  Am J Case Rep       Date:  2021-12-14
  4 in total

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