Literature DB >> 21785563

Pulsed Nano-Electrospray Ionization: Characterization of Temporal Response and Implementation with a Flared Inlet Capillary.

Jared M Bushey1, Desmond A Kaplan, Ryan M Danell, Gary L Glish.   

Abstract

The temporal response of pulsed nano-electrospray ionization mass spectrometry (nano-ESI-MS) was studied and its influence on ion formation and detection was characterized. Rise and decay times for the mass resolved ion current were determined to be 20 ± 3 msec and 61 ± 5 msec, respectively, which led to a maximum pulse rate of 12 Hz. Pulsed nano-ESI operation was demonstrated from a multi-sprayer source controlled by a high voltage pulsing circuit constructed in-house. The desired source mode of operation (e.g. pulsing or continuous) can be realized solely by controlling the voltage applied to each sprayer.

Entities:  

Year:  2009        PMID： 21785563      PMCID： PMC3141176          DOI： 10.1080/10739140902831313

Source DB:  PubMed          Journal:  Instrum Sci Technol        ISSN： 1073-9149            Impact factor:   1.584


  21 in total

1.  High-sensitivity analysis and sequencing of peptides and proteins by quadrupole ion trap mass spectrometry.

Authors:  A Marina; M A García; J P Albar; J Yagüe; J A López de Castro; J Vázquez
Journal:  J Mass Spectrom       Date:  1999-01       Impact factor: 1.982

2.  High accuracy mass measurement of peptides with internal calibration using a dual electrospray ionization sprayer system for protein identification.

Authors:  Feng Zhou; Wenqing Shui; Yu Lu; Pengyuan Yang; Yinlong Guo
Journal:  Rapid Commun Mass Spectrom       Date:  2002       Impact factor: 2.419

3.  Naturally and externally pulsed electrospray.

Authors:  Junfei Wei; Wenqing Shui; Feng Zhou; Yu Lu; Kankai Chen; Guobing Xu; Pengyuan Yang
Journal:  Mass Spectrom Rev       Date:  2002 May-Jun       Impact factor: 10.946

Review 4.  The basics of mass spectrometry in the twenty-first century.

Authors:  Gary L Glish; Richard W Vachet
Journal:  Nat Rev Drug Discov       Date:  2003-02       Impact factor: 84.694

5.  Accurate mass measurement in nano-electrospray ionization mass spectrometry by alternate switching of high voltage between sample and reference sprayers.

Authors:  Yoshinori Satomi; Yoichiro Kudo; Kyoko Sasaki; Toshiharu Hase; Toshifumi Takao
Journal:  Rapid Commun Mass Spectrom       Date:  2005       Impact factor: 2.419

6.  Porous polymer monolith assisted electrospray.

Authors:  Terry Koerner; Kiera Turck; Laurie Brown; Richard D Oleschuk
Journal:  Anal Chem       Date:  2004-11-01       Impact factor: 6.986

7.  Comparison of liquid chromatography using triple quadrupole and quadrupole ion trap mass analyzers to determine pesticide residues in oranges.

Authors:  Carla Soler; Jordi Mañes; Yolanda Picó
Journal:  J Chromatogr A       Date:  2005-03-04       Impact factor: 4.759

8.  A new approach for the study of gas-phase ion-ion reactions using electrospray ionization.

Authors:  R R Ogorzalek Loo; H R Udseth; R D Smith
Journal:  J Am Soc Mass Spectrom       Date:  1992-10       Impact factor: 3.109

9.  Micro-electrospray mass spectrometry: Ultra-high-sensitivity analysis of peptides and proteins.

Authors:  M R Emmett; R M Caprioli
Journal:  J Am Soc Mass Spectrom       Date:  1994-07       Impact factor: 3.109

10.  Analytical properties of the nanoelectrospray ion source.

Authors:  M Wilm; M Mann
Journal:  Anal Chem       Date:  1996-01-01       Impact factor: 6.986
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  7 in total

1.  On the time scale of internal energy relaxation of AP-MALDI and nano-ESI ions in a quadrupole ion trap.

Authors:  Philip M Remes; Gary L Glish
Journal:  J Am Soc Mass Spectrom       Date:  2009-06-21       Impact factor: 3.109

2.  Improved Differential Ion Mobility Separations Using Linked Scans of Carrier Gas Composition and Compensation Field.

Authors:  Brandon G Santiago; Rachel A Harris; Samantha L Isenberg; Mark E Ridgeway; Alice L Pilo; Desmond A Kaplan; Gary L Glish
Journal:  J Am Soc Mass Spectrom       Date:  2015-07-07       Impact factor: 3.109

3.  Triboelectric nanogenerators for sensitive nano-coulomb molecular mass spectrometry.

Authors:  Anyin Li; Yunlong Zi; Hengyu Guo; Zhong Lin Wang; Facundo M Fernández
Journal:  Nat Nanotechnol       Date:  2017-02-27       Impact factor: 39.213

4.  Increased Ion Transmission for Differential Ion Mobility Combined with Mass Spectrometry by Implementation of a Flared Inlet Capillary.

Authors:  Matthew T Campbell; Gary L Glish
Journal:  J Am Soc Mass Spectrom       Date:  2016-10-17       Impact factor: 3.109

5.  Direct Mass Spectrometry Analysis of Complex Mixtures by Nanoelectrospray with Simultaneous Atmospheric Pressure Chemical Ionization and Electrophoretic Separation Capabilities.

Authors:  Dmytro S Kulyk; Devin J Swiner; Taghi Sahraeian; Abraham K Badu-Tawiah
Journal:  Anal Chem       Date:  2019-09-06       Impact factor: 6.986

6.  Perturbation-induced high-frequency pulsing of nano-ESI with facile ion selection at atmospheric pressure.

Authors:  William P McMahon; Kaveh Jorabchi
Journal:  Analyst       Date:  2020-11-09       Impact factor: 4.616

7.  Optimization of peptide separations by differential ion mobility spectrometry.

Authors:  Samantha L Isenberg; Paul M Armistead; Gary L Glish
Journal:  J Am Soc Mass Spectrom       Date:  2014-07-03       Impact factor: 3.109
  7 in total

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