Literature DB >> 21677985

Investigation of self-immolative linkers in the design of hydrogen peroxide activated metalloprotein inhibitors.

Jody L Major Jourden1, Kevin B Daniel, Seth M Cohen.   

Abstract

A series of self-immolative boronic ester protected methyl salicylates and metal-binding groups with various linking strategies have been investigated for their use in the design of matrix metalloproteinase proinhibitors.

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Year:  2011        PMID： 21677985      PMCID： PMC3682828          DOI： 10.1039/c1cc12526e

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  26 in total

1.  Design and therapeutic application of matrix metalloproteinase inhibitors.

Authors:  M Whittaker; C D Floyd; P Brown; A J Gearing
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Review 3.  The inflammatory response in stroke.

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4.  Enzymatic activation of a matrix metalloproteinase inhibitor.

Authors:  Jody L Major Jourden; Seth M Cohen
Journal:  Chem Commun (Camb)       Date:  2010-01-18       Impact factor: 6.222

5.  Towards bioreductively activated prodrugs: Fe(III) complexes of hydroxamic acids and the MMP inhibitor marimastat.

Authors:  Timothy W Failes; Trevor W Hambley
Journal:  J Inorg Biochem       Date:  2006-11-15       Impact factor: 4.155

6.  A pro-chelator triggered by hydrogen peroxide inhibits iron-promoted hydroxyl radical formation.

Authors:  Louise K Charkoudian; David M Pham; Katherine J Franz
Journal:  J Am Chem Soc       Date:  2006-09-27       Impact factor: 15.419

7.  From sensors to silencers: quinoline- and benzimidazole-sulfonamides as inhibitors for zinc proteases.

Authors:  Matthieu Rouffet; César Augusto F de Oliveira; Yael Udi; Arpita Agrawal; Irit Sagi; J Andrew McCammon; Seth M Cohen
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8.  Bioreversible derivatives of phenol. 2. Reactivity of carbonate esters with fatty acid-like structures towards hydrolysis in aqueous solutions.

Authors:  Jesper Østergaard; Claus Larsen
Journal:  Molecules       Date:  2007-10-30       Impact factor: 4.411

9.  Phase II trial of the histone deacetylase inhibitor pivaloyloxymethyl butyrate (Pivanex, AN-9) in advanced non-small cell lung cancer.

Authors:  Tony Reid; Frank Valone; William Lipera; David Irwin; Warren Paroly; Ron Natale; Sunil Sreedharan; Harold Keer; Bert Lum; Frank Scappaticci; Anish Bhatnagar
Journal:  Lung Cancer       Date:  2004-09       Impact factor: 5.705

10.  Activation of sulfonate ester based matrix metalloproteinase proinhibitors by hydrogen peroxide.

Authors:  Kevin B Daniel; Jody L Major Jourden; Kimberly E Negoescu; Seth M Cohen
Journal:  J Biol Inorg Chem       Date:  2010-11-04       Impact factor: 3.358
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  15 in total

1.  A Cell-Permeable Fluorescent Prochelator Responds to Hydrogen Peroxide and Metal Ions by Decreasing Fluorescence.

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2.  Readily accessible fluorescent probes for sensitive biological imaging of hydrogen peroxide.

Authors:  Kevin B Daniel; Arpita Agrawal; Marianne Manchester; Seth M Cohen
Journal:  Chembiochem       Date:  2013-02-21       Impact factor: 3.164

Review 3.  Excessive Reactive Oxygen Species and Exotic DNA Lesions as an Exploitable Liability.

Authors:  Safnas F AbdulSalam; Fathima Shazna Thowfeik; Edward J Merino
Journal:  Biochemistry       Date:  2016-09-13       Impact factor: 3.162

4.  Exploring hydrogen peroxide responsive thiazolidinone-based prodrugs.

Authors:  Christian Perez; Jean-Philippe Monserrat; Yao Chen; Seth M Cohen
Journal:  Chem Commun (Camb)       Date:  2015-04-28       Impact factor: 6.222

5.  A prochelator with a modular masking group featuring hydrogen peroxide activation with concurrent fluorescent reporting.

Authors:  Andrew T Franks; Katherine J Franz
Journal:  Chem Commun (Camb)       Date:  2014-10-07       Impact factor: 6.222

6.  Dual-responsive nanoparticles release cargo upon exposure to matrix metalloproteinase and reactive oxygen species.

Authors:  Kevin B Daniel; Cassandra E Callmann; Nathan C Gianneschi; Seth M Cohen
Journal:  Chem Commun (Camb)       Date:  2016-02-04       Impact factor: 6.222

Review 7.  Current progress in Reactive Oxygen Species (ROS)-Responsive materials for biomedical applications.

Authors:  Sue Hyun Lee; Mukesh K Gupta; Jae Beum Bang; Hojae Bae; Hak-Joon Sung
Journal:  Adv Healthc Mater       Date:  2013-01-25       Impact factor: 9.933

Review 8.  Reactive oxygen species-activated nanomaterials as theranostic agents.

Authors:  Kye S Kim; Dongwon Lee; Chul Gyu Song; Peter M Kang
Journal:  Nanomedicine (Lond)       Date:  2015-09-02       Impact factor: 5.307

9.  Evaluating prodrug strategies for esterase-triggered release of alcohols.

Authors:  Christian Perez; Kevin B Daniel; Seth M Cohen
Journal:  ChemMedChem       Date:  2013-08-08       Impact factor: 3.466

10.  Biocompatible polymeric nanoparticles degrade and release cargo in response to biologically relevant levels of hydrogen peroxide.

Authors:  Caroline de Gracia Lux; Shivanjali Joshi-Barr; Trung Nguyen; Enas Mahmoud; Eric Schopf; Nadezda Fomina; Adah Almutairi
Journal:  J Am Chem Soc       Date:  2012-09-17       Impact factor: 15.419
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