Literature DB >> 26696280

Dual-responsive nanoparticles release cargo upon exposure to matrix metalloproteinase and reactive oxygen species.

Kevin B Daniel1, Cassandra E Callmann1, Nathan C Gianneschi1, Seth M Cohen1.   

Abstract

Micellar nanoparticles were designed to be responsive to matrix metalloproteinases (MMPs) and reactive oxygen species (ROS), each of which is upregulated in the pathology of inflammatory diseases. The amphiphilic polymer-based nanoparticle system consists of a hydrophilic shell responsible for particle morphology change and aggregation, together with a hydrophobic block designed to release cargo in the presence of ROS.

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Year:  2016        PMID: 26696280      PMCID: PMC4729588          DOI: 10.1039/c5cc09164k

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  26 in total

Review 1.  Matrix metalloproteinases.

Authors:  H Nagase; J F Woessner
Journal:  J Biol Chem       Date:  1999-07-30       Impact factor: 5.157

Review 2.  The inflammatory response in stroke.

Authors:  Qing Wang; Xian Nan Tang; Midori A Yenari
Journal:  J Neuroimmunol       Date:  2006-12-26       Impact factor: 3.478

3.  Mitochondrial redox control of matrix metalloproteinase signaling in resistance arteries.

Authors:  Rhian M Touyz
Journal:  Arterioscler Thromb Vasc Biol       Date:  2006-04       Impact factor: 8.311

4.  Controlling and switching the morphology of micellar nanoparticles with enzymes.

Authors:  Ti-Hsuan Ku; Miao-Ping Chien; Matthew P Thompson; Robert S Sinkovits; Norman H Olson; Timothy S Baker; Nathan C Gianneschi
Journal:  J Am Chem Soc       Date:  2011-04-04       Impact factor: 15.419

5.  Enzyme-directed assembly of a nanoparticle probe in tumor tissue.

Authors:  Miao-Ping Chien; Matthew P Thompson; Christopher V Barback; Ti-Hsuan Ku; David J Hall; Nathan C Gianneschi
Journal:  Adv Mater       Date:  2013-05-28       Impact factor: 30.849

6.  Enzyme-Responsive Nanoparticles for Targeted Accumulation and Prolonged Retention in Heart Tissue after Myocardial Infarction.

Authors:  Mary M Nguyen; Andrea S Carlini; Miao-Ping Chien; Sonya Sonnenberg; Colin Luo; Rebecca L Braden; Kent G Osborn; Yiwen Li; Nathan C Gianneschi; Karen L Christman
Journal:  Adv Mater       Date:  2015-08-25       Impact factor: 30.849

7.  A dual-responsive mesoporous silica nanoparticle for tumor-triggered targeting drug delivery.

Authors:  Dong Xiao; Hui-Zhen Jia; Jing Zhang; Chen-Wei Liu; Ren-Xi Zhuo; Xian-Zheng Zhang
Journal:  Small       Date:  2013-09-17       Impact factor: 13.281

8.  Enzyme-directed assembly of nanoparticles in tumors monitored by in vivo whole animal imaging and ex vivo super-resolution fluorescence imaging.

Authors:  Miao-Ping Chien; Andrea S Carlini; Dehong Hu; Christopher V Barback; Anthony M Rush; David J Hall; Galya Orr; Nathan C Gianneschi
Journal:  J Am Chem Soc       Date:  2013-12-05       Impact factor: 15.419

9.  Peptides displayed as high density brush polymers resist proteolysis and retain bioactivity.

Authors:  Angela P Blum; Jacquelin K Kammeyer; Jian Yin; Dustin T Crystal; Anthony M Rush; Michael K Gilson; Nathan C Gianneschi
Journal:  J Am Chem Soc       Date:  2014-10-14       Impact factor: 15.419

10.  Matrix metalloproteinases and blood-brain barrier disruption in acute ischemic stroke.

Authors:  Shaheen E Lakhan; Annette Kirchgessner; Deborah Tepper; Aidan Leonard
Journal:  Front Neurol       Date:  2013-04-03       Impact factor: 4.003

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  6 in total

Review 1.  ROS-responsive drug delivery systems.

Authors:  Jing Liang; Bin Liu
Journal:  Bioeng Transl Med       Date:  2016-07-05

Review 2.  ROS-responsive drug delivery systems for biomedical applications.

Authors:  Wenhui Tao; Zhonggui He
Journal:  Asian J Pharm Sci       Date:  2017-12-02       Impact factor: 6.598

Review 3.  Stimulus-Responsive Nanomedicines for Disease Diagnosis and Treatment.

Authors:  Gengqi Liu; Jonathan F Lovell; Lei Zhang; Yumiao Zhang
Journal:  Int J Mol Sci       Date:  2020-09-02       Impact factor: 5.923

Review 4.  Inflammation-responsive delivery systems for the treatment of chronic inflammatory diseases.

Authors:  Zhengyu Deng; Shiyong Liu
Journal:  Drug Deliv Transl Res       Date:  2021-04-15       Impact factor: 4.617

Review 5.  Nanomaterials-Mediated Therapeutics and Diagnosis Strategies for Myocardial Infarction.

Authors:  Qingbo Lv; Boxuan Ma; Wujiao Li; Guosheng Fu; Xiaoyu Wang; Yun Xiao
Journal:  Front Chem       Date:  2022-07-07       Impact factor: 5.545

6.  Order from Disorder with Intrinsically Disordered Peptide Amphiphiles.

Authors:  Guy Jacoby; Merav Segal Asher; Tamara Ehm; Inbal Abutbul Ionita; Hila Shinar; Salome Azoulay-Ginsburg; Ido Zemach; Gil Koren; Dganit Danino; Michael M Kozlov; Roey J Amir; Roy Beck
Journal:  J Am Chem Soc       Date:  2021-07-26       Impact factor: 15.419

  6 in total

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