Literature DB >> 21547985

Pan-Src family kinase inhibitors replace Sox2 during the direct reprogramming of somatic cells.

Judith Staerk1, Costas A Lyssiotis, Lea A Medeiro, Michael Bollong, Ruth K Foreman, Shoutian Zhu, Michael Garcia, Qing Gao, Laure C Bouchez, Luke L Lairson, Bradley D Charette, Lubica Supekova, Jeffrey Janes, Achim Brinker, Charles Y Cho, Rudolf Jaenisch, Peter G Schultz.   

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Year:  2011        PMID: 21547985      PMCID: PMC3409461          DOI: 10.1002/anie.201101042

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN: 1433-7851            Impact factor:   15.336


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  19 in total

Review 1.  A renaissance for SRC.

Authors:  Timothy J Yeatman
Journal:  Nat Rev Cancer       Date:  2004-06       Impact factor: 60.716

Review 2.  Apparent activity in high-throughput screening: origins of compound-dependent assay interference.

Authors:  Natasha Thorne; Douglas S Auld; James Inglese
Journal:  Curr Opin Chem Biol       Date:  2010-04-22       Impact factor: 8.822

3.  Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4.

Authors:  Costas A Lyssiotis; Ruth K Foreman; Judith Staerk; Michael Garcia; Divya Mathur; Styliani Markoulaki; Jacob Hanna; Luke L Lairson; Bradley D Charette; Laure C Bouchez; Michael Bollong; Conrad Kunick; Achim Brinker; Charles Y Cho; Peter G Schultz; Rudolf Jaenisch
Journal:  Proc Natl Acad Sci U S A       Date:  2009-05-15       Impact factor: 11.205

4.  Tgfbeta signal inhibition cooperates in the induction of iPSCs and replaces Sox2 and cMyc.

Authors:  Nimet Maherali; Konrad Hochedlinger
Journal:  Curr Biol       Date:  2009-09-17       Impact factor: 10.834

5.  The Src family of tyrosine kinases is important for embryonic stem cell self-renewal.

Authors:  Cecilia Annerén; Chad A Cowan; Douglas A Melton
Journal:  J Biol Chem       Date:  2004-05-17       Impact factor: 5.157

6.  In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen.

Authors:  David Plouffe; Achim Brinker; Case McNamara; Kerstin Henson; Nobutaka Kato; Kelli Kuhen; Advait Nagle; Francisco Adrián; Jason T Matzen; Paul Anderson; Tae-Gyu Nam; Nathanael S Gray; Arnab Chatterjee; Jeff Janes; S Frank Yan; Richard Trager; Jeremy S Caldwell; Peter G Schultz; Yingyao Zhou; Elizabeth A Winzeler
Journal:  Proc Natl Acad Sci U S A       Date:  2008-06-25       Impact factor: 11.205

7.  Chemical genetics identifies c-Src as an activator of primitive ectoderm formation in murine embryonic stem cells.

Authors:  Malcolm A Meyn; Thomas E Smithgall
Journal:  Sci Signal       Date:  2009-10-13       Impact factor: 8.192

8.  A small-molecule inhibitor of tgf-Beta signaling replaces sox2 in reprogramming by inducing nanog.

Authors:  Justin K Ichida; Joel Blanchard; Kelvin Lam; Esther Y Son; Julia E Chung; Dieter Egli; Kyle M Loh; Ava C Carter; Francesco P Di Giorgio; Kathryn Koszka; Danwei Huangfu; Hidenori Akutsu; David R Liu; Lee L Rubin; Kevin Eggan
Journal:  Cell Stem Cell       Date:  2009-10-08       Impact factor: 24.633

9.  Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation.

Authors:  J H Hanke; J P Gardner; R L Dow; P S Changelian; W H Brissette; E J Weringer; B A Pollok; P A Connelly
Journal:  J Biol Chem       Date:  1996-01-12       Impact factor: 5.157

10.  Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds.

Authors:  Danwei Huangfu; René Maehr; Wenjun Guo; Astrid Eijkelenboom; Melinda Snitow; Alice E Chen; Douglas A Melton
Journal:  Nat Biotechnol       Date:  2008-06-22       Impact factor: 54.908

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  22 in total

Review 1.  Generation of pluripotent stem cells without the use of genetic material.

Authors:  Akon Higuchi; Qing-Dong Ling; S Suresh Kumar; Murugan A Munusamy; Abdullah A Alarfaj; Yung Chang; Shih-Hsuan Kao; Ke-Chen Lin; Han-Chow Wang; Akihiro Umezawa
Journal:  Lab Invest       Date:  2014-11-03       Impact factor: 5.662

Review 2.  Chemical approaches to stem cell biology and therapeutics.

Authors:  Wenlin Li; Ke Li; Wanguo Wei; Sheng Ding
Journal:  Cell Stem Cell       Date:  2013-09-05       Impact factor: 24.633

Review 3.  Inducing pluripotency in vitro: recent advances and highlights in induced pluripotent stem cells generation and pluripotency reprogramming.

Authors:  I K Rony; A Baten; J A Bloomfield; M E Islam; M M Billah; K D Islam
Journal:  Cell Prolif       Date:  2015-01-29       Impact factor: 6.831

Review 4.  An Insight into DNA-free Reprogramming Approaches to Generate Integration-free Induced Pluripotent Stem Cells for Prospective Biomedical Applications.

Authors:  Manash P Borgohain; Krishna Kumar Haridhasapavalan; Chandrima Dey; Poulomi Adhikari; Rajkumar P Thummer
Journal:  Stem Cell Rev Rep       Date:  2019-04       Impact factor: 5.739

Review 5.  Master regulators in development: Views from the Drosophila retinal determination and mammalian pluripotency gene networks.

Authors:  Trevor L Davis; Ilaria Rebay
Journal:  Dev Biol       Date:  2016-12-13       Impact factor: 3.582

Review 6.  Pluripotent stem cells: induction and self-renewal.

Authors:  R Abu-Dawud; N Graffmann; S Ferber; W Wruck; J Adjaye
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2018-07-05       Impact factor: 6.237

Review 7.  Mechanisms underlying the formation of induced pluripotent stem cells.

Authors:  Federico González; Danwei Huangfu
Journal:  Wiley Interdiscip Rev Dev Biol       Date:  2015-09-18       Impact factor: 5.814

Review 8.  Progress in the reprogramming of somatic cells.

Authors:  Tianhua Ma; Min Xie; Timothy Laurent; Sheng Ding
Journal:  Circ Res       Date:  2013-02-01       Impact factor: 17.367

9.  c-Yes tyrosine kinase is a potent suppressor of ES cell differentiation and antagonizes the actions of its closest phylogenetic relative, c-Src.

Authors:  Xiong Zhang; Malcolm A Meyn; Thomas E Smithgall
Journal:  ACS Chem Biol       Date:  2013-08-15       Impact factor: 5.100

10.  Replacing reprogramming factors with antibodies selected from combinatorial antibody libraries.

Authors:  Joel W Blanchard; Jia Xie; Nadja El-Mecharrafie; Simon Gross; Sohyon Lee; Richard A Lerner; Kristin K Baldwin
Journal:  Nat Biotechnol       Date:  2017-09-11       Impact factor: 54.908

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