Literature DB >> 21276819

Separated interface nerve electrode prevents direct current induced nerve damage.

D Michael Ackermann1, Niloy Bhadra, Emily L Foldes, Kevin L Kilgore.   

Abstract

Direct current, DC, can be used to quickly and reversibly block activity in excitable tissue, or to quickly and reversibly increase or decrease the natural excitability of a neuronal population. However, the practical use of DC to control neuronal activity has been extremely limited due to the rapid tissue damage caused by its use. We show that a separated interface nerve electrode, SINE, is a much safer method to deliver DC to excitable tissue and may be valuable as a laboratory research tool or potentially for clinical treatment of disease.
Copyright © 2011 Elsevier B.V. All rights reserved.

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Year:  2011        PMID： 21276819      PMCID： PMC3099145          DOI： 10.1016/j.jneumeth.2011.01.016

Source DB:  PubMed          Journal:  J Neurosci Methods        ISSN： 0165-0270            Impact factor:   2.390


  19 in total

1.  The effect of subthreshold prepulses on the recruitment order in a nerve trunk analyzed in a simple and a realistic volume conductor model.

Authors:  K E Deurloo; J Holsheimer; P Bergveld
Journal:  Biol Cybern       Date:  2001-10       Impact factor: 2.086

2.  Direct current electrical conduction block of peripheral nerve.

Authors:  Niloy Bhadra; Kevin L Kilgore
Journal:  IEEE Trans Neural Syst Rehabil Eng       Date:  2004-09       Impact factor: 3.802

3.  Charge density and charge per phase as cofactors in neural injury induced by electrical stimulation.

Authors:  D B McCreery; W F Agnew; T G Yuen; L Bullara
Journal:  IEEE Trans Biomed Eng       Date:  1990-10       Impact factor: 4.538

4.  Design, fabrication and evaluation of a conforming circumpolar peripheral nerve cuff electrode for acute experimental use.

Authors:  Emily L Foldes; D Michael Ackermann; Niloy Bhadra; Kevin L Kilgore; Narendra Bhadra
Journal:  J Neurosci Methods       Date:  2010-12-25       Impact factor: 2.390

5.  The use of direct current to cause selective block of large fibres in peripheral nerves.

Authors:  J G Whitwam; C Kidd
Journal:  Br J Anaesth       Date:  1975-11       Impact factor: 9.166

6.  Effects of ramped amplitude waveforms on the onset response of high-frequency mammalian nerve block.

Authors:  J D Miles; K L Kilgore; N Bhadra; E A Lahowetz
Journal:  J Neural Eng       Date:  2007-11-12       Impact factor: 5.379

7.  Local anaesthetic block protects against electrically-induced damage in peripheral nerve.

Authors:  W F Agnew; D B McCreery; T G Yuen; L A Bullara
Journal:  J Biomed Eng       Date:  1990-07

8.  Differential block of conduction of larger fibers in peripheral nerve by direct current.

Authors:  M Manfredi
Journal:  Arch Ital Biol       Date:  1970-01       Impact factor: 1.000

9.  Adverse acute and chronic effects of electrical defibrillation and cardioversion on implanted unipolar cardiac pacing systems.

Authors:  P A Levine; S S Barold; R D Fletcher; P Talbot
Journal:  J Am Coll Cardiol       Date:  1983-06       Impact factor: 24.094

10.  The role of non-myelinated vagal afferent fibres from the lungs in the genesis of tachypnoea in the rabbit.

Authors:  A Guz; D W Trenchard
Journal:  J Physiol       Date:  1971-03       Impact factor: 5.182
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  10 in total

1.  Combined KHFAC + DC nerve block without onset or reduced nerve conductivity after block.

Authors:  Manfred Franke; Tina Vrabec; Jesse Wainright; Niloy Bhadra; Narendra Bhadra; Kevin Kilgore
Journal:  J Neural Eng       Date:  2014-08-13       Impact factor: 5.379

2.  Characterization of high capacitance electrodes for the application of direct current electrical nerve block.

Authors:  Tina Vrabec; Niloy Bhadra; Jesse Wainright; Narendra Bhadra; Manfred Franke; Kevin Kilgore
Journal:  Med Biol Eng Comput       Date:  2015-09-11       Impact factor: 2.602

3.  A Carbon Slurry Separated Interface Nerve Electrode for Electrical Block of Nerve Conduction.

Authors:  Tina L Vrabec; Jesse S Wainright; Narendra Bhadra; Laura Shaw; Kevin L Kilgore; Niloy Bhadra
Journal:  IEEE Trans Neural Syst Rehabil Eng       Date:  2019-04-04       Impact factor: 3.802

4.  Fuzzy Logic Control of Heartrate by Electrical Block of Vagus Nerve.

Authors:  Shane A Bender; David B Green; Robert J Daniels; Kevin L Kilgore; Niloy Bhadra; Tina L Vrabec
Journal:  Int IEEE EMBS Conf Neural Eng       Date:  2021-06-02

5.  Evaluation of Activated Carbon and Platinum Black as High-Capacitance Materials for Platinum Electrodes.

Authors:  Andrew Goh; David Roberts; Jesse Wainright; Narendra Bhadra; Kevin Kilgore; Niloy Bhadra; Tina Vrabec
Journal:  Sensors (Basel)       Date:  2022-06-03       Impact factor: 3.847

6.  Safe direct current stimulation to expand capabilities of neural prostheses.

Authors:  Gene Y Fridman; Charles C Della Santina
Journal:  IEEE Trans Neural Syst Rehabil Eng       Date:  2013-03       Impact factor: 3.802

Review 7.  Reversible nerve conduction block using kilohertz frequency alternating current.

Authors:  Kevin L Kilgore; Niloy Bhadra
Journal:  Neuromodulation       Date:  2013-08-07

Review 8.  Reversible conduction block in peripheral nerve using electrical waveforms.

Authors:  Niloy Bhadra; Tina L Vrabec; Narendra Bhadra; Kevin L Kilgore
Journal:  Bioelectron Med (Lond)       Date:  2017-12-14

Review 9.  Implantable Direct Current Neural Modulation: Theory, Feasibility, and Efficacy.

Authors:  Felix P Aplin; Gene Y Fridman
Journal:  Front Neurosci       Date:  2019-04-18       Impact factor: 4.677

10.  A Hydrogel-Based Microfluidic Nerve Cuff for Neuromodulation of Peripheral Nerves.

Authors:  Raviraj Thakur; Felix P Aplin; Gene Y Fridman
Journal:  Micromachines (Basel)       Date:  2021-12-08       Impact factor: 2.891
  10 in total

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