Literature DB >> 2104662

A gene that encodes a protein consisting solely of zinc finger domains is preferentially expressed in transformed mouse cells.

M Ernoult-Lange1, M Kress, D Hamer.   

Abstract

We describe the cloning and characterization of the mouse MOK-2 gene, a new member of the Krüppel family of zinc finger proteins. Sequencing of both cDNA and genomic clones showed that the predicted MOK-2 protein consists of seven zinc finger domains with only five additional amino acids. The finger domains of MOK-2 are highly homologous to one another but not to those of other zinc finger proteins. MOK-2 is preferentially expressed in transformed cell lines, brain tissue, and testis tissue. Its possible role in cellular transformation is discussed.

Entities:  

Mesh：

Substances：

Year:  1990        PMID： 2104662      PMCID： PMC360772          DOI： 10.1128/mcb.10.1.418-421.1990

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN： 0270-7306            Impact factor:   4.272


  34 in total

1.  A simplifying concept in tumor virology: virus-specific "pleiotropic effectors".

Authors:  R Weil; E Salomon; E May; P May
Journal:  Cold Spring Harb Symp Quant Biol       Date:  1975

2.  A conserved family of nuclear proteins containing structural elements of the finger protein encoded by Krüppel, a Drosophila segmentation gene.

Authors:  R Schuh; W Aicher; U Gaul; S Côté; A Preiss; D Maier; E Seifert; U Nauber; C Schröder; R Kemler
Journal:  Cell       Date:  1986-12-26       Impact factor: 41.582

3.  Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction.

Authors:  P Chomczynski; N Sacchi
Journal:  Anal Biochem       Date:  1987-04       Impact factor: 3.365

4.  A nerve growth factor-induced gene encodes a possible transcriptional regulatory factor.

Authors:  J Milbrandt
Journal:  Science       Date:  1987-11-06       Impact factor: 47.728

Review 5.  Zinc fingers: gilt by association.

Authors:  R M Evans; S M Hollenberg
Journal:  Cell       Date:  1988-01-15       Impact factor: 41.582

6.  Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domain.

Authors:  J T Kadonaga; K R Carner; F R Masiarz; R Tjian
Journal:  Cell       Date:  1987-12-24       Impact factor: 41.582

7.  A multigene family encoding several "finger" structures is present and differentially active in mammalian genomes.

Authors:  K Chowdhury; U Deutsch; P Gruss
Journal:  Cell       Date:  1987-03-13       Impact factor: 41.582

8.  Identification of an amplified, highly expressed gene in a human glioma.

Authors:  K W Kinzler; S H Bigner; D D Bigner; J M Trent; M L Law; S J O'Brien; A J Wong; B Vogelstein
Journal:  Science       Date:  1987-04-03       Impact factor: 47.728

9.  DNA sequencing with chain-terminating inhibitors.

Authors:  F Sanger; S Nicklen; A R Coulson
Journal:  Proc Natl Acad Sci U S A       Date:  1977-12       Impact factor: 11.205

10.  Xfin: an embryonic gene encoding a multifingered protein in Xenopus.

Authors:  A Ruiz i Altaba; H Perry-O'Keefe; D A Melton
Journal:  EMBO J       Date:  1987-10       Impact factor: 11.598
View more
  10 in total

1.  In vivo and in vitro interaction between human transcription factor MOK2 and nuclear lamin A/C.

Authors:  Caroline Dreuillet; Jeanne Tillit; Michel Kress; Michèle Ernoult-Lange
Journal:  Nucleic Acids Res       Date:  2002-11-01       Impact factor: 16.971

Review 2.  Zinc finger protein genes in the mouse genome.

Authors:  A Ashworth; P Denny
Journal:  Mamm Genome       Date:  1991       Impact factor: 2.957

3.  Localization of zinc finger Mok2 gene to mouse chromosome 6, a new region of homology with human chromosome 19.

Authors:  V Arranz; M Kress; M Ernoult-Lange
Journal:  Mamm Genome       Date:  1996-01       Impact factor: 2.957

4.  Human proviral mRNAs down regulated in choriocarcinoma encode a zinc finger protein related to Krüppel.

Authors:  N Kato; K Shimotohno; D VanLeeuwen; M Cohen
Journal:  Mol Cell Biol       Date:  1990-08       Impact factor: 4.272

5.  Characterization of the gene encoding hydroxylamine oxidoreductase in Nitrosomonas europaea.

Authors:  L A Sayavedra-Soto; N G Hommes; D J Arp
Journal:  J Bacteriol       Date:  1994-01       Impact factor: 3.490

6.  The KUP gene, located on human chromosome 14, encodes a protein with two distant zinc fingers.

Authors:  P Chardin; G Courtois; M G Mattei; S Gisselbrecht
Journal:  Nucleic Acids Res       Date:  1991-04-11       Impact factor: 16.971

7.  Human and mouse MOK2 proteins are associated with nuclear ribonucleoprotein components and bind specifically to RNA and DNA through their zinc finger domains.

Authors:  V Arranz; F Harper; Y Florentin; E Puvion; M Kress; M Ernoult-Lange
Journal:  Mol Cell Biol       Date:  1997-04       Impact factor: 4.272

8.  Human and mouse Krüppel-like (MOK2) orthologue genes encode two different zinc finger proteins.

Authors:  M Ernoult-Lange; V Arranz; M Le Coniat; R Berger; M Kress
Journal:  J Mol Evol       Date:  1995-12       Impact factor: 2.395

9.  Two monomers of yeast transcription factor ADR1 bind a palindromic sequence symmetrically to activate ADH2 expression.

Authors:  S K Thukral; A Eisen; E T Young
Journal:  Mol Cell Biol       Date:  1991-03       Impact factor: 4.272

10.  New nucleotide sequence data on the EMBL File Server.

Authors: 
Journal:  Nucleic Acids Res       Date:  1990-06-11       Impact factor: 16.971
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.