PURPOSE: To compare cardiac output (CO) and blood volumes measured by COstatus(®) (Transonic Systems Inc., NY, USA) versus PiCCO (Philips IntelliVue MP40 with PiCCO-technology module M3012A#10, Netherlands) in adult ICU patients. METHODS: This was a prospective single-center study. Each of the 30 patients studied received a 5-Fr Pulsiocath femoral arterial and a standard central venous catheter. Twenty ml of iced 5% dextrose solution was injected for PiCCO measurements. For COstatus measurements, an extracorporeal arteriovenous loop, with two sensors placed on it, was connected between the Pulsiocath femoral arterial and central venous catheters. Blood was circulated through this loop at 12 ml/min for 5-8 min using a pump. Twenty ml of warm saline was injected into the venous side for measurements. For each method, three injections were averaged for comparison. RESULTS: A good agreement for measured CO (range 3.65-16.3 l/min) with a percentage error of 20% was observed, with r = 0.95, bias = -0.037 l/min. PiCCO's global end-diastolic volume (GEDV) was 2.5 times larger than the analogous COstatus's total end-diastolic volume (TEDV) [TEDV = 0.28 × GEDV + 176 ml]. PiCCO's intrathoracic blood volume (ITBV) was larger than the analogous COstatus's central blood volume (CBV) [CBV = 0.73 × (ITBV) +78 ml]. CONCLUSIONS: CO measured by COstatus was found to be equivalent and hence interchangeable with PiCCO in this study population. COstatus blood volumes were found to be within the expected physiological range whilst PiCCO blood volumes were significantly higher, which was also observed in other studies. Future studies using 3D echo/MRI are required to validate these blood volumes.
PURPOSE: To compare cardiac output (CO) and blood volumes measured by COstatus(®) (Transonic Systems Inc., NY, USA) versus PiCCO (Philips IntelliVue MP40 with PiCCO-technology module M3012A#10, Netherlands) in adult ICU patients. METHODS: This was a prospective single-center study. Each of the 30 patients studied received a 5-Fr Pulsiocath femoral arterial and a standard central venous catheter. Twenty ml of iced 5% dextrose solution was injected for PiCCO measurements. For COstatus measurements, an extracorporeal arteriovenous loop, with two sensors placed on it, was connected between the Pulsiocath femoral arterial and central venous catheters. Blood was circulated through this loop at 12 ml/min for 5-8 min using a pump. Twenty ml of warm saline was injected into the venous side for measurements. For each method, three injections were averaged for comparison. RESULTS: A good agreement for measured CO (range 3.65-16.3 l/min) with a percentage error of 20% was observed, with r = 0.95, bias = -0.037 l/min. PiCCO's global end-diastolic volume (GEDV) was 2.5 times larger than the analogous COstatus's total end-diastolic volume (TEDV) [TEDV = 0.28 × GEDV + 176 ml]. PiCCO's intrathoracic blood volume (ITBV) was larger than the analogous COstatus's central blood volume (CBV) [CBV = 0.73 × (ITBV) +78 ml]. CONCLUSIONS: CO measured by COstatus was found to be equivalent and hence interchangeable with PiCCO in this study population. COstatus blood volumes were found to be within the expected physiological range whilst PiCCO blood volumes were significantly higher, which was also observed in other studies. Future studies using 3D echo/MRI are required to validate these blood volumes.
Authors: Willem P de Boode; Arno F J van Heijst; Jeroen C W Hopman; Ronald B Tanke; Hans G van der Hoeven; Kian D Liem Journal: Pediatr Crit Care Med Date: 2010-01 Impact factor: 3.624
Authors: Martin Boehne; Florian Schmidt; Lars Witt; Harald Köditz; Michael Sasse; Robert Sümpelmann; Harald Bertram; Armin Wessel; Wilhelm Alexander Osthaus Journal: Pediatr Cardiol Date: 2012-02-14 Impact factor: 1.655
Authors: Alejandro A Floh; Gustavo La Rotta; Julius Z Wermelt; Patricia Bastero-Miñón; V Ben Sivarajan; Tilman Humpl Journal: Intensive Care Med Date: 2013-02-22 Impact factor: 17.440
Authors: Massimo Antonelli; Elie Azoulay; Marc Bonten; Jean Chastre; Giuseppe Citerio; Giorgio Conti; Daniel De Backer; Herwig Gerlach; Goran Hedenstierna; Michael Joannidis; Duncan Macrae; Jordi Mancebo; Salvatore M Maggiore; Alexandre Mebazaa; Jean-Charles Preiser; Jerôme Pugin; Jan Wernerman; Haibo Zhang Journal: Intensive Care Med Date: 2011-01-12 Impact factor: 17.440