Literature DB >> 20571209

In vivo real-time rectal wall dosimetry for prostate radiotherapy.

Nicholas Hardcastle1, Dean L Cutajar, Peter E Metcalfe, Michael L F Lerch, Vladimir L Perevertaylo, Wolfgang A Tomé, Anatoly B Rosenfeld.   

Abstract

Rectal balloons are used in external beam prostate radiotherapy to provide reproducible anatomy and rectal dose reductions. This is an investigation into the combination of a MOSFET radiation detector with a rectal balloon for realtime in vivo rectal wall dosimetry. The MOSFET used in the study is a radiation detector that provides a water equivalent depth of measurement of 70 microm. Two MOSFETs were combined in a face-to-face orientation. The reproducibility, sensitivity and angular dependence were measured for the dual MOSFET in a 6 MV photon beam. The dual MOSFET was combined with a rectal balloon and irradiated with hypothetical prostate treatments in a phantom. The anterior rectal wall dose was measured in real time and compared with the planning system calculated dose. The dual MOSFET showed angular dependence within +/-2.5% in the azimuth and +2.5%/-4% in the polar axes. When compared with an ion chamber measurement in a phantom, the dual MOSFET agreed within 2.5% for a range of radiation path lengths and incident angles. The dual MOSFET had reproducible sensitivity for fraction sizes of 2-10 Gy. For the hypothetical prostate treatments the measured anterior rectal wall dose was 2.6 and 3.2% lower than the calculated dose for 3DCRT and IMRT plans. This was expected due to limitations of the dose calculation method used at the balloon cavity interface. A dual MOSFET combined with a commercial rectal balloon was shown to provide reproducible measurements of the anterior rectal wall dose in real time. The measured anterior rectal wall dose agreed with the expected dose from the treatment plan for 3DCRT and IMRT plans. The dual MOSFET could be read out in real time during the irradiation, providing the capability for real-time dose monitoring of the rectal wall dose during treatment.

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Year:  2010        PMID: 20571209      PMCID: PMC2911784          DOI: 10.1088/0031-9155/55/13/019

Source DB:  PubMed          Journal:  Phys Med Biol        ISSN: 0031-9155            Impact factor:   3.609


  38 in total

1.  Rectal wall sparing by dosimetric effect of rectal balloon used during intensity-modulated radiation therapy (IMRT) for prostate cancer.

Authors:  Bin S Teh; Lei Dong; John E McGary; Wei-Yuan Mai; Walter Grant; E Brian Butler
Journal:  Med Dosim       Date:  2005       Impact factor: 1.482

2.  An analysis of an implantable dosimeter system for external beam therapy.

Authors:  Robert D Black; Charles W Scarantino; Gregory G Mann; Mitchell S Anscher; Robert D Ornitz; Benjamin E Nelms
Journal:  Int J Radiat Oncol Biol Phys       Date:  2005-09-01       Impact factor: 7.038

3.  Calibration of a mosfet detection system for 6-MV in vivo dosimetry.

Authors:  P Scalchi; P Francescon
Journal:  Int J Radiat Oncol Biol Phys       Date:  1998-03-01       Impact factor: 7.038

4.  Characterization of a new MOSFET detector configuration for in vivo skin dosimetry.

Authors:  Paolo Scalchi; Paolo Francescon; Priyadarshini Rajaguru
Journal:  Med Phys       Date:  2005-06       Impact factor: 4.071

5.  Fractionation and protraction for radiotherapy of prostate carcinoma.

Authors:  D J Brenner; E J Hall
Journal:  Int J Radiat Oncol Biol Phys       Date:  1999-03-15       Impact factor: 7.038

6.  Rectal wall sparing effect of three different endorectal balloons in 3D conformal and IMRT prostate radiotherapy.

Authors:  Emile N J Th van Lin; Aswin L Hoffmann; Peter van Kollenburg; Jan Willem Leer; Andries G Visser
Journal:  Int J Radiat Oncol Biol Phys       Date:  2005-10-01       Impact factor: 7.038

7.  Initial clinical results of an in vivo dosimeter during external beam radiation therapy.

Authors:  Charles W Scarantino; Christopher J Rini; Migdalia Aquino; Tammy B Carrea; Robert D Ornitz; Mitchell S Anscher; Robert D Black
Journal:  Int J Radiat Oncol Biol Phys       Date:  2005-06-01       Impact factor: 7.038

8.  The effect of an endorectal balloon and off-line correction on the interfraction systematic and random prostate position variations: a comparative study.

Authors:  Emile N J Th van Lin; Lisette P van der Vight; J Alfred Witjes; Henkjan J Huisman; Jan Willem Leer; Andries G Visser
Journal:  Int J Radiat Oncol Biol Phys       Date:  2005-01-01       Impact factor: 7.038

9.  Dose escalation with 3D conformal treatment: five year outcomes, treatment optimization, and future directions.

Authors:  G E Hanks; A L Hanlon; T E Schultheiss; W H Pinover; B Movsas; B E Epstein; M A Hunt
Journal:  Int J Radiat Oncol Biol Phys       Date:  1998-06-01       Impact factor: 7.038

10.  Dose escalation with three-dimensional conformal radiation therapy affects the outcome in prostate cancer.

Authors:  M J Zelefsky; S A Leibel; P B Gaudin; G J Kutcher; N E Fleshner; E S Venkatramen; V E Reuter; W R Fair; C C Ling; Z Fuks
Journal:  Int J Radiat Oncol Biol Phys       Date:  1998-06-01       Impact factor: 7.038

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  12 in total

1.  Real-time eye lens dose monitoring during cerebral angiography procedures.

Authors:  M J Safari; J H D Wong; K A A Kadir; N K Thorpe; D L Cutajar; M Petasecca; M L F Lerch; A B Rosenfeld; K H Ng
Journal:  Eur Radiol       Date:  2015-05-23       Impact factor: 5.315

Review 2.  In vivo dosimetry: trends and prospects for brachytherapy.

Authors:  G Kertzscher; A Rosenfeld; S Beddar; K Tanderup; J E Cygler
Journal:  Br J Radiol       Date:  2014-07-08       Impact factor: 3.039

3.  Towards in vivo Dosimetry for Prostate Radiotherapy with a Transperineal Ultrasound Array: A Simulation Study.

Authors:  Mengxiao Wang; Pratik Samant; Siqi Wang; Jack Merill; Yong Chen; Salahuddin Ahmad; Dengwang Li; Liangzhong Xiang
Journal:  IEEE Trans Radiat Plasma Med Sci       Date:  2020-08-10

4.  Preliminary evaluation of the dosimetric accuracy of the in vivo plastic scintillation detector OARtrac system for prostate cancer treatments.

Authors:  Slade J Klawikowski; Clint Zeringue; Landon S Wootton; Geoffrey S Ibbott; Sam Beddar
Journal:  Phys Med Biol       Date:  2014-04-15       Impact factor: 3.609

5.  In-phantom dose verification of prostate IMRT and VMAT deliveries using plastic scintillation detectors.

Authors:  David Klein; Tina Marie Briere; Rajat Kudchadker; Louis Archambault; Luc Beaulieu; Andrew Lee; Sam Beddar
Journal:  Radiat Meas       Date:  2012-08-24       Impact factor: 1.898

6.  Real-time in vivo rectal wall dosimetry using MOSkin detectors during linac based stereotactic radiotherapy with rectal displacement.

Authors:  Kimberley Legge; Peter B Greer; Daryl J O'Connor; Lee Wilton; Matthew Richardson; Perry Hunter; Alex Wilfert; Jarad Martin; Anatoly Rosenfeld; Dean Cutajar
Journal:  Radiat Oncol       Date:  2017-02-27       Impact factor: 3.481

7.  In vivo endorectal dosimetry of prostate tomotherapy using dual MOSkin detectors.

Authors:  Sarah J Alnaghy; Shrikant Deshpande; Dean L Cutajar; Kemal Berk; Peter Metcalfe; Anatoly B Rosenfeld
Journal:  J Appl Clin Med Phys       Date:  2015-05-08       Impact factor: 2.102

8.  A study on rectal dose measurement in phantom and in vivo using Gafchromic EBT3 film in IMRT and CyberKnife treatments of carcinoma of prostate.

Authors:  K Ganapathy; P G G Kurup; V Murali; M Muthukumaran; S Balaji Subramanian; J Velmurugan
Journal:  J Med Phys       Date:  2013-07

9.  Characterization of MOSkin detector for in vivo skin dose measurement during megavoltage radiotherapy.

Authors:  Wei Loong Jong; Jeannie Hsiu Ding Wong; Ngie Min Ung; Kwan Hoong Ng; Gwo Fuang Ho; Dean L Cutajar; Anatoly B Rosenfeld
Journal:  J Appl Clin Med Phys       Date:  2014-09-08       Impact factor: 2.102

10.  Commissioning and implementation of an implantable dosimeter for radiation therapy.

Authors:  Ivan Buzurovic; Timothy N Showalter; Matthew T Studenski; Robert B Den; Adam P Dicker; Junsheng Cao; Ying Xiao; Yan Yu; Amy Harrison
Journal:  J Appl Clin Med Phys       Date:  2013-03-04       Impact factor: 2.102

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