OBJECTIVE: The purpose of this article is to review the pharmacokinetic and pharmacodynamic properties of gadoxetate disodium (Gd-EOB-DTPA), to describe a workflow-optimized pulse sequence protocol, and to illustrate the imaging appearance of focal lesions in the noncirrhotic liver. CONCLUSION: Gd-EOB-DTPA allows a comprehensive evaluation of the liver with the acquisition of both dynamic and hepatocyte phase images. This provides potential additional information, especially for the detection and characterization of small liver lesions. However, protocol optimization is necessary for improved image quality and workflow.
OBJECTIVE: The purpose of this article is to review the pharmacokinetic and pharmacodynamic properties of gadoxetate disodium (Gd-EOB-DTPA), to describe a workflow-optimized pulse sequence protocol, and to illustrate the imaging appearance of focal lesions in the noncirrhotic liver. CONCLUSION:Gd-EOB-DTPA allows a comprehensive evaluation of the liver with the acquisition of both dynamic and hepatocyte phase images. This provides potential additional information, especially for the detection and characterization of small liver lesions. However, protocol optimization is necessary for improved image quality and workflow.
Authors: Julian A Luetkens; Patrick A Kupczyk; Jonas Doerner; Rolf Fimmers; Winfried A Willinek; Hans H Schild; Guido M Kukuk Journal: Eur Radiol Date: 2015-04-23 Impact factor: 5.315
Authors: Stephen R Bowen; Jatinder Saini; Tobias R Chapman; Robert S Miyaoka; Paul E Kinahan; George A Sandison; Tony Wong; Hubert J Vesselle; Matthew J Nyflot; Smith Apisarnthanarax Journal: Radiother Oncol Date: 2015-04-28 Impact factor: 6.280
Authors: Anum Aslam; Amita Kamath; Bradley Spieler; Mark Maschiocchi; Carl F Sabottke; Victoria Chernyak; Sara C Lewis Journal: Abdom Radiol (NY) Date: 2021-04-15
Authors: Hanke J Schalkx; Marijn van Stralen; Kenneth Coenegrachts; Maurice A A J van den Bosch; Charlotte S van Kessel; Richard van Hillegersberg; Karel J van Erpecum; Helena M Verkooijen; Josien P W Pluim; Wouter B Veldhuis; Maarten S van Leeuwen Journal: Eur Radiol Date: 2014-07-05 Impact factor: 5.315