Literature DB >> 20361281

Insufficient bone regenerate after intramedullary femoral lengthening: risk factors and classification system.

Mohamed Kenawey1, Christian Krettek, Emmanouil Liodakis, Rupert Meller, Stefan Hankemeier.   

Abstract

BACKGROUND: Control of distraction rate with an intramedullary skeletal kinetic distractor (ISKD) may be problematic and a high distraction rate may result in insufficient bone regenerate. QUESTIONS/PURPOSES: Are distraction problems preventable when using the ISKD, and what are the risk factors for and radiologic types of insufficient bone regenerate during ISKD lengthening? PATIENTS AND METHODS: We analyzed 37 consecutive ISKD femoral lengthening procedures in 35 patients with a mean age 33 ± 11 years and minimum followup of 12 months (average, 27 ± 9 months; range, 12-55 months). The average length gain was 42.8 ± 12.9 mm.
RESULTS: Eight patients had problems during distraction: seven had "runaway nails" and one had a nondistracting nail. Insufficient bone regenerate developed in eight patients. Important risk factors were a distraction rate greater than 1.5 mm/day (9.1 times higher risk), age 30 years or older, smoking, and lengthening greater than 4 cm. Less important risk factors identified were creation of the osteotomy at the site of previous trauma or surgery and acute correction of associated deformities. We proposed a radiologic classification for failure of bone regeneration: partial regenerate failure (Type I) or complete failure resulting in a segmental defect subdivided according to a length of 3 cm or less (Type IIa) or greater than 3 cm (Type IIb).
CONCLUSIONS: Distraction problems with the ISKD were related mostly to internal malfunction of the lengthening mechanism. A distraction rate greater than 1.5 mm/day should be avoided in femoral intramedullary lengthening. Smoking should be a contraindication for femoral lengthening. LEVEL OF EVIDENCE: Level II, prognostic study. See Guidelines for Authors for a complete description of levels of evidence.

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Year:  2010        PMID: 20361281      PMCID: PMC3008908          DOI: 10.1007/s11999-010-1332-6

Source DB:  PubMed          Journal:  Clin Orthop Relat Res        ISSN: 0009-921X            Impact factor:   4.176


  28 in total

1.  The effect of distraction upon bone, muscle, and periosteum.

Authors:  N Yasui; H Kojimoto; H Shimizu; Y Shimomura
Journal:  Orthop Clin North Am       Date:  1991-10       Impact factor: 2.472

2.  Mechanical characterization of a totally intramedullary gradual elongation nail.

Authors:  J M Guichet; R S Casar
Journal:  Clin Orthop Relat Res       Date:  1997-04       Impact factor: 4.176

3.  The tension-stress effect on the genesis and growth of tissues: Part II. The influence of the rate and frequency of distraction.

Authors:  G A Ilizarov
Journal:  Clin Orthop Relat Res       Date:  1989-02       Impact factor: 4.176

Review 4.  Problems, obstacles, and complications of limb lengthening by the Ilizarov technique.

Authors:  D Paley
Journal:  Clin Orthop Relat Res       Date:  1990-01       Impact factor: 4.176

5.  The role of corticotomy and osteotomy in the treatment of bone defects using the Ilizarov technique.

Authors:  R Brutscher; B A Rahn; A Rüter; S M Perren
Journal:  J Orthop Trauma       Date:  1993       Impact factor: 2.512

6.  Factors affecting callus distraction in limb lengthening.

Authors:  N Yasui; H Kojimoto; K Sasaki; A Kitada; H Shimizu; Y Shimomura
Journal:  Clin Orthop Relat Res       Date:  1993-08       Impact factor: 4.176

7.  Osteoneogenesis and its influencing factors during treatment with the Ilizarov method.

Authors:  B Fink; M Krieger; J M Strauss; C Opheys; S Menkhaus; J Fischer; W Rüther
Journal:  Clin Orthop Relat Res       Date:  1996-02       Impact factor: 4.176

8.  Variables affecting time to bone healing during limb lengthening.

Authors:  J Fischgrund; D Paley; C Suter
Journal:  Clin Orthop Relat Res       Date:  1994-04       Impact factor: 4.176

9.  Improved comfort in lower limb lengthening with the intramedullary skeletal kinetic distractor. Principles and preliminary clinical experiences.

Authors:  Stefan Hankemeier; Hans-Christoph Pape; Thomas Gosling; Tobias Hufner; Martinus Richter; Christian Krettek
Journal:  Arch Orthop Trauma Surg       Date:  2004-01-27       Impact factor: 3.067

10.  Bone lengthening in rabbits by callus distraction. The role of periosteum and endosteum.

Authors:  H Kojimoto; N Yasui; T Goto; S Matsuda; Y Shimomura
Journal:  J Bone Joint Surg Br       Date:  1988-08
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  18 in total

1.  Femoral lengthening with lengthening over a nail has fewer complications than intramedullary skeletal kinetic distraction.

Authors:  Shahab Mahboubian; Matthew Seah; Austin T Fragomen; S Robert Rozbruch
Journal:  Clin Orthop Relat Res       Date:  2011-12-06       Impact factor: 4.176

2.  Comparison of 39 post-traumatic tibia bone transports performed with and without the use of an intramedullary rod: the long-term outcomes.

Authors:  Emmanouil Liodakis; Mohamed Kenawey; Christian Krettek; Ulrich Wiebking; Stefan Hankemeier
Journal:  Int Orthop       Date:  2010-07-22       Impact factor: 3.075

3.  Upright MRI measurement of mechanical axis and frontal plane alignment as a new technique: a comparative study with weight bearing full length radiographs.

Authors:  Emmanouil Liodakis; Mohamed Kenawey; Iosifina Doxastaki; Christian Krettek; Carl Haasper; Stefan Hankemeier
Journal:  Skeletal Radiol       Date:  2010-12-18       Impact factor: 2.199

4.  Precision of the PRECICE internal bone lengthening nail.

Authors:  Yatin M Kirane; Austin T Fragomen; S Robert Rozbruch
Journal:  Clin Orthop Relat Res       Date:  2014-12       Impact factor: 4.176

5.  Complications and functional, psychological outcomes of bilateral tibial lengthening over intramedullary nail: evidence from Vietnam.

Authors:  Luong Nguyen Van; Doan Le Van
Journal:  Int Orthop       Date:  2021-05-12       Impact factor: 3.075

6.  Complications of the Intramedullary Skeletal Kinetic Distractor (ISKD) in distraction osteogenesis.

Authors:  Dong Hoon Lee; Keun Jung Ryu; Hae Ryong Song; Soo-Hong Han
Journal:  Clin Orthop Relat Res       Date:  2014-12       Impact factor: 4.176

7.  Current concepts of leg lengthening.

Authors:  Carol C Hasler; Andreas H Krieg
Journal:  J Child Orthop       Date:  2012-03-21       Impact factor: 1.548

8.  Bone marrow aspirate concentrate and platelet-rich plasma enhanced bone healing in distraction osteogenesis of the tibia.

Authors:  Dong Hoon Lee; Keun Jung Ryu; Jin Woo Kim; Kyung Chung Kang; Young Rak Choi
Journal:  Clin Orthop Relat Res       Date:  2014-12       Impact factor: 4.176

9.  Mechanical solutions to salvage failed distraction osteogenesis in large bone defect management.

Authors:  Dmitry Y Borzunov; Alexander L Shastov
Journal:  Int Orthop       Date:  2018-06-23       Impact factor: 3.075

10.  Internal lengthening device for congenital femoral deficiency and fibular hemimelia.

Authors:  Lior Shabtai; Stacy C Specht; Shawn C Standard; John E Herzenberg
Journal:  Clin Orthop Relat Res       Date:  2014-12       Impact factor: 4.176

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