Literature DB >> 20161365

The Columbia University Sub-micron Charged Particle Beam.

Gerhard Randers-Pehrson1, Gary W Johnson, Stephen A Marino, Yanping Xu, Alexander D Dymnikov, David J Brenner.   

Abstract

A lens system consisting of two electrostatic quadrupole triplets has been designed and constructed at the Radiological Research Accelerator Facility (RARAF) of Columbia University. The lens system has been used to focus 6-MeV (4)He ions to a beam spot in air with a diameter of 0.8 µm. The quadrupole electrodes can withstand voltages high enough to focus (4)He ions up to 10 MeV and protons up to 5 MeV. The quadrupole triplet design is novel in that alignment is made through precise construction and the relative strengths of the quadrupoles are accomplished by the lengths of the elements, so that the magnitudes of the voltages required for focusing are nearly identical. The insulating sections between electrodes have had ion implantation to improve the voltage stability of the lens. The lens design employs Russian symmetry for the quadrupole elements.

Entities:  

Year:  2009        PMID: 20161365      PMCID: PMC2778032          DOI: 10.1016/j.nima.2009.08.041

Source DB:  PubMed          Journal:  Nucl Instrum Methods Phys Res A        ISSN: 0168-9002            Impact factor:   1.455


  3 in total

1.  The Columbia University single-ion microbeam.

Authors:  G Randers-Pehrson; C R Geard; G Johnson; C D Elliston; D J Brenner
Journal:  Radiat Res       Date:  2001-08       Impact factor: 2.841

2.  Irradiation of parts of individual cells.

Authors:  R E ZIRKLE; W BLOOM
Journal:  Science       Date:  1953-05-08       Impact factor: 47.728

Review 3.  The PTB microbeam: a versatile instrument for radiobiological research.

Authors:  K Greif; W Beverung; F Langner; D Frankenberg; A Gellhaus; F Banaz-Yasar
Journal:  Radiat Prot Dosimetry       Date:  2006-12-12       Impact factor: 0.972

  3 in total
  9 in total

1.  50 Years of the Radiological Research Accelerator Facility (RARAF).

Authors:  Stephen A Marino
Journal:  Radiat Res       Date:  2017-01-31       Impact factor: 2.841

2.  The Columbia University proton-induced soft x-ray microbeam.

Authors:  Andrew D Harken; Gerhard Randers-Pehrson; Gary W Johnson; David J Brenner
Journal:  Nucl Instrum Methods Phys Res B       Date:  2011-09-15       Impact factor: 1.377

3.  An ultra-thin Schottky diode as a transmission particle detector for biological microbeams.

Authors:  Michael Grad; Andrew Harken; Gerhard Randers-Pehrson; Daniel Attinger; David J Brenner
Journal:  J Instrum       Date:  2012-12       Impact factor: 1.415

4.  A Horizontal Multi-Purpose Microbeam System.

Authors:  Y Xu; G Randers-Pehrson; S A Marino; G Garty; A Harken; D J Brenner
Journal:  Nucl Instrum Methods Phys Res A       Date:  2018-02-04       Impact factor: 1.455

5.  Metabolic oxygen consumption measurement with a single-cell biosensor after particle microbeam irradiation.

Authors:  Yanping Xu; Bo Zhang; Mark Messerli; Gerhard Randers-Pehrson; Tom K Hei; David J Brenner
Journal:  Radiat Environ Biophys       Date:  2014-10-22       Impact factor: 1.925

6.  Novel neutron sources at the Radiological Research Accelerator Facility.

Authors:  Yanping Xu; Guy Garty; Stephen A Marino; Thomas N Massey; Gerhard Randers-Pehrson; Gary W Johnson; David J Brenner
Journal:  J Instrum       Date:  2012-03-16       Impact factor: 1.415

7.  Automated microbeam observation environment for biological analysis-Custom portable environmental control applied to a vertical microbeam system.

Authors:  Matthew J England; Alan W Bigelow; Michael J Merchant; Eirini Velliou; David Welch; David J Brenner; Karen J Kirkby
Journal:  Sens Actuators B Chem       Date:  2016-08-16       Impact factor: 7.460

8.  Radiation-Induced Lipid Peroxidation Triggers Ferroptosis and Synergizes with Ferroptosis Inducers.

Authors:  Ling F Ye; Kunal R Chaudhary; Fereshteh Zandkarimi; Andrew D Harken; Connor J Kinslow; Pavan S Upadhyayula; Athanassios Dovas; Dominique M Higgins; Hui Tan; Yan Zhang; Manuela Buonanno; Tony J C Wang; Tom K Hei; Jeffrey N Bruce; Peter D Canoll; Simon K Cheng; Brent R Stockwell
Journal:  ACS Chem Biol       Date:  2020-01-14       Impact factor: 4.634

9.  SPICE-NIRS microbeam: a focused vertical system for proton irradiation of a single cell for radiobiological research.

Authors:  Teruaki Konishi; Masakazu Oikawa; Noriyoshi Suya; Takahiro Ishikawa; Takeshi Maeda; Alisa Kobayashi; Naoko Shiomi; Kumiko Kodama; Tsuyoshi Hamano; Shino Homma-Takeda; Mayu Isono; Kotaro Hieda; Yukio Uchihori; Yoshiyuki Shirakawa
Journal:  J Radiat Res       Date:  2013-01-03       Impact factor: 2.724

  9 in total

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