Literature DB >> 20154661

The (un)targeted cancer kinome.

Oleg Fedorov1, Susanne Müller, Stefan Knapp.   

Abstract

Entities:  

Year:  2010        PMID： 20154661     DOI： 10.1038/nchembio.297

Source DB:  PubMed          Journal:  Nat Chem Biol        ISSN： 1552-4450            Impact factor:   15.040


× No keyword cloud information.
  39 in total

Review 1.  The protein kinase complement of the human genome.

Authors:  G Manning; D B Whyte; R Martinez; T Hunter; S Sudarsanam
Journal:  Science       Date:  2002-12-06       Impact factor: 47.728

2.  Recognizing and exploiting differences between RNAi and small-molecule inhibitors.

Authors:  William A Weiss; Stephen S Taylor; Kevan M Shokat
Journal:  Nat Chem Biol       Date:  2007-12       Impact factor: 15.040

3.  Assessment of chemical coverage of kinome space and its implications for kinase drug discovery.

Authors:  Paul Bamborough; David Drewry; Gavin Harper; Gary K Smith; Klaus Schneider
Journal:  J Med Chem       Date:  2008-12-25       Impact factor: 7.446

Review 4.  Challenges and opportunities in defining the essential cancer kinome.

Authors:  Brendan D Manning
Journal:  Sci Signal       Date:  2009-03-24       Impact factor: 8.192

5.  Kinase requirements in human cells: II. Genetic interaction screens identify kinase requirements following HPV16 E7 expression in cancer cells.

Authors:  Amy Baldwin; Wenliang Li; Miranda Grace; Joseph Pearlberg; Ed Harlow; Karl Münger; Dorre A Grueneberg
Journal:  Proc Natl Acad Sci U S A       Date:  2008-10-23       Impact factor: 11.205

6.  Structure and allosteric effects of low-molecular-weight activators on the protein kinase PDK1.

Authors:  Valerie Hindie; Adriana Stroba; Hua Zhang; Laura A Lopez-Garcia; Leila Idrissova; Stefan Zeuzem; Daniel Hirschberg; Francis Schaeffer; Thomas J D Jørgensen; Matthias Engel; Pedro M Alzari; Ricardo M Biondi
Journal:  Nat Chem Biol       Date:  2009-08-30       Impact factor: 15.040

Review 7.  Factors underlying sensitivity of cancers to small-molecule kinase inhibitors.

Authors:  Pasi A Jänne; Nathanael Gray; Jeff Settleman
Journal:  Nat Rev Drug Discov       Date:  2009-07-24       Impact factor: 84.694

8.  Kinase requirements in human cells: I. Comparing kinase requirements across various cell types.

Authors:  Dorre A Grueneberg; Sebastien Degot; Joseph Pearlberg; Wenliang Li; Joan E Davies; Amy Baldwin; Wilson Endege; John Doench; Jacqueline Sawyer; Yanhui Hu; Frederick Boyce; Jun Xian; Karl Munger; Ed Harlow
Journal:  Proc Natl Acad Sci U S A       Date:  2008-10-23       Impact factor: 11.205

9.  Structural basis for the autoinhibition of c-Abl tyrosine kinase.

Authors:  Bhushan Nagar; Oliver Hantschel; Matthew A Young; Klaus Scheffzek; Darren Veach; William Bornmann; Bayard Clarkson; Giulio Superti-Furga; John Kuriyan
Journal:  Cell       Date:  2003-03-21       Impact factor: 41.582

10.  Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition.

Authors:  Jeffrey F Ohren; Huifen Chen; Alexander Pavlovsky; Christopher Whitehead; Erli Zhang; Peter Kuffa; Chunhong Yan; Patrick McConnell; Cindy Spessard; Craig Banotai; W Thomas Mueller; Amy Delaney; Charles Omer; Judith Sebolt-Leopold; David T Dudley; Iris K Leung; Cathlin Flamme; Joseph Warmus; Michael Kaufman; Stephen Barrett; Haile Tecle; Charles A Hasemann
Journal:  Nat Struct Mol Biol       Date:  2004-11-14       Impact factor: 15.369
View more
  107 in total

1.  Expression and purification of Src-family kinases for solution NMR studies.

Authors:  Andrea Piserchio; David Cowburn; Ranajeet Ghose
Journal:  Methods Mol Biol       Date:  2012

2.  New approaches to rewarding pharmaceutical innovation.

Authors:  Paul Grootendorst; Aidan Hollis; David K Levine; Thomas Pogge; Aled M Edwards
Journal:  CMAJ       Date:  2010-12-13       Impact factor: 8.262

Review 3.  Functional proteomics to dissect tyrosine kinase signalling pathways in cancer.

Authors:  Walter Kolch; Andrew Pitt
Journal:  Nat Rev Cancer       Date:  2010-08-19       Impact factor: 60.716

4.  Comprehensive characterization of the Published Kinase Inhibitor Set.

Authors:  Jonathan M Elkins; Vita Fedele; Marta Szklarz; Kamal R Abdul Azeez; Eidarus Salah; Jowita Mikolajczyk; Sergei Romanov; Nikolai Sepetov; Xi-Ping Huang; Bryan L Roth; Ayman Al Haj Zen; Denis Fourches; Eugene Muratov; Alex Tropsha; Joel Morris; Beverly A Teicher; Mark Kunkel; Eric Polley; Karen E Lackey; Francis L Atkinson; John P Overington; Paul Bamborough; Susanne Müller; Daniel J Price; Timothy M Willson; David H Drewry; Stefan Knapp; William J Zuercher
Journal:  Nat Biotechnol       Date:  2015-10-26       Impact factor: 54.908

5.  The ins and outs of selective kinase inhibitor development.

Authors:  Susanne Müller; Apirat Chaikuad; Nathanael S Gray; Stefan Knapp
Journal:  Nat Chem Biol       Date:  2015-11       Impact factor: 15.040

6.  Computational Modeling of Kinase Inhibitor Selectivity.

Authors:  Govindan Subramanian; Manish Sud
Journal:  ACS Med Chem Lett       Date:  2010-07-28       Impact factor: 4.345

7.  HPLC-UV method for simultaneous determination of MK-1775 and AZD-7762 in both acetonitrile-aqueous solution and mouse plasma.

Authors:  Kareem Ebeid; Giang N Ho; Aliasger K Salem
Journal:  J Chromatogr B Analyt Technol Biomed Life Sci       Date:  2016-12-30       Impact factor: 3.205

8.  The protein kinase MAP3K19 phosphorylates MAP2Ks and thereby activates ERK and JNK kinases and increases viability of KRAS-mutant lung cancer cells.

Authors:  Van T Hoang; Katherine Nyswaner; Pedro Torres-Ayuso; John Brognard
Journal:  J Biol Chem       Date:  2020-04-30       Impact factor: 5.157

9.  Protein AMPylation by an Evolutionarily Conserved Pseudokinase.

Authors:  Anju Sreelatha; Samantha S Yee; Victor A Lopez; Brenden C Park; Lisa N Kinch; Sylwia Pilch; Kelly A Servage; Junmei Zhang; Jenny Jiou; Monika Karasiewicz-Urbańska; Małgorzata Łobocka; Nick V Grishin; Kim Orth; Roza Kucharczyk; Krzysztof Pawłowski; Diana R Tomchick; Vincent S Tagliabracci
Journal:  Cell       Date:  2018-09-27       Impact factor: 41.582

10.  The human kinome and kinase inhibition.

Authors:  Krisna C Duong-Ly; Jeffrey R Peterson
Journal:  Curr Protoc Pharmacol       Date:  2013-03
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.