Literature DB >> 18007642

Recognizing and exploiting differences between RNAi and small-molecule inhibitors.

William A Weiss1, Stephen S Taylor, Kevan M Shokat.   

Abstract

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Year:  2007        PMID： 18007642      PMCID： PMC2924165          DOI： 10.1038/nchembio1207-739

Source DB:  PubMed          Journal:  Nat Chem Biol        ISSN： 1552-4450            Impact factor:   15.040


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  26 in total

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Authors:  Mar Carmena; William C Earnshaw
Journal:  Nat Rev Mol Cell Biol       Date:  2003-11       Impact factor: 94.444

2.  Identification and prediction of promiscuous aggregating inhibitors among known drugs.

Authors:  James Seidler; Susan L McGovern; Thompson N Doman; Brian K Shoichet
Journal:  J Med Chem       Date:  2003-10-09       Impact factor: 7.446

3.  Aurora-A kinase maintains the fidelity of early and late mitotic events in HeLa cells.

Authors:  Tomotoshi Marumoto; Shinobu Honda; Toshihiro Hara; Masayuki Nitta; Toru Hirota; Eiji Kohmura; Hideyuki Saya
Journal:  J Biol Chem       Date:  2003-10-01       Impact factor: 5.157

Review 4.  Aurora-kinase inhibitors as anticancer agents.

Authors:  Nicholas Keen; Stephen Taylor
Journal:  Nat Rev Cancer       Date:  2004-12       Impact factor: 60.716

Review 5.  Features of selective kinase inhibitors.

Authors:  Zachary A Knight; Kevan M Shokat
Journal:  Chem Biol       Date:  2005-06

Review 6.  Aurora kinases: shining lights on the therapeutic horizon?

Authors:  Paul D Andrews
Journal:  Oncogene       Date:  2005-07-28       Impact factor: 9.867

7.  Activation of apoptosis in vivo by a hydrocarbon-stapled BH3 helix.

Authors:  Loren D Walensky; Andrew L Kung; Iris Escher; Thomas J Malia; Scott Barbuto; Renee D Wright; Gerhard Wagner; Gregory L Verdine; Stanley J Korsmeyer
Journal:  Science       Date:  2004-09-03       Impact factor: 47.728

8.  Positive and negative roles of p85 alpha and p85 beta regulatory subunits of phosphoinositide 3-kinase in insulin signaling.

Authors:  Kohjiro Ueki; David A Fruman; Claudine M Yballe; Mathias Fasshauer; Johannes Klein; Tomoichiro Asano; Lewis C Cantley; C Ronald Kahn
Journal:  J Biol Chem       Date:  2003-09-22       Impact factor: 5.157

9.  The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint.

Authors:  Silke Hauf; Richard W Cole; Sabrina LaTerra; Christine Zimmer; Gisela Schnapp; Rainer Walter; Armin Heckel; Jacques van Meel; Conly L Rieder; Jan-Michael Peters
Journal:  J Cell Biol       Date:  2003-04-21       Impact factor: 10.539

10.  Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores.

Authors:  Claire Ditchfield; Victoria L Johnson; Anthony Tighe; Rebecca Ellston; Carolyn Haworth; Trevor Johnson; Andrew Mortlock; Nicholas Keen; Stephen S Taylor
Journal:  J Cell Biol       Date:  2003-04-28       Impact factor: 10.539
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  123 in total

1.  A small molecule modulates circadian rhythms through phosphorylation of the period protein.

Authors:  Jae Wook Lee; Tsuyoshi Hirota; Eric C Peters; Michael Garcia; Rodolfo Gonzalez; Charles Y Cho; Xu Wu; Peter G Schultz; Steve A Kay
Journal:  Angew Chem Int Ed Engl       Date:  2011-09-26       Impact factor: 15.336

2.  A Role for Widely Interspaced Zinc Finger (WIZ) in Retention of the G9a Methyltransferase on Chromatin.

Authors:  Jeremy M Simon; Joel S Parker; Feng Liu; Scott B Rothbart; Slimane Ait-Si-Ali; Brian D Strahl; Jian Jin; Ian J Davis; Amber L Mosley; Samantha G Pattenden
Journal:  J Biol Chem       Date:  2015-09-03       Impact factor: 5.157

3.  Design of Small Molecules That Compete with Nucleotide Binding to an Engineered Oncogenic KRAS Allele.

Authors:  Yan Zhang; Marie-Hélène Larraufie; Leila Musavi; Hemanth Akkiraju; Lewis M Brown; Brent R Stockwell
Journal:  Biochemistry       Date:  2018-02-06       Impact factor: 3.162

4.  Isoform-selective phosphoinositide 3'-kinase inhibitors inhibit CXCR4 signaling and overcome stromal cell-mediated drug resistance in chronic lymphocytic leukemia: a novel therapeutic approach.

Authors:  Matthias Niedermeier; Bryan T Hennessy; Zachary A Knight; Marina Henneberg; Jianhua Hu; Antonina V Kurtova; William G Wierda; Michael J Keating; Kevan M Shokat; Jan A Burger
Journal:  Blood       Date:  2009-03-24       Impact factor: 22.113

Review 5.  Precision Control of CRISPR-Cas9 Using Small Molecules and Light.

Authors:  Soumyashree A Gangopadhyay; Kurt J Cox; Debasish Manna; Donghyun Lim; Basudeb Maji; Qingxuan Zhou; Amit Choudhary
Journal:  Biochemistry       Date:  2019-01-22       Impact factor: 3.162

6.  A High-Throughput Platform to Identify Small-Molecule Inhibitors of CRISPR-Cas9.

Authors:  Basudeb Maji; Soumyashree A Gangopadhyay; Miseon Lee; Mengchao Shi; Peng Wu; Robert Heler; Beverly Mok; Donghyun Lim; Sachini U Siriwardena; Bishwajit Paul; Vlado Dančík; Amedeo Vetere; Michael F Mesleh; Luciano A Marraffini; David R Liu; Paul A Clemons; Bridget K Wagner; Amit Choudhary
Journal:  Cell       Date:  2019-05-02       Impact factor: 41.582

7.  Phenotypic Screening Combined with Machine Learning for Efficient Identification of Breast Cancer-Selective Therapeutic Targets.

Authors:  Prson Gautam; Alok Jaiswal; Tero Aittokallio; Hassan Al-Ali; Krister Wennerberg
Journal:  Cell Chem Biol       Date:  2019-05-02       Impact factor: 8.116

8.  It takes two to tango: Dual inhibition of PI3K and MAPK in rhabdomyosarcoma.

Authors:  Arman Jahangiri; William A Weiss
Journal:  Clin Cancer Res       Date:  2013-10-04       Impact factor: 12.531

Review 9.  Combining targeted therapies: practical issues to consider at the bench and bedside.

Authors:  Jordi Rodon; Jose Perez; Razelle Kurzrock
Journal:  Oncologist       Date:  2010-01-15

10.  Analyzing fission yeast multidrug resistance mechanisms to develop a genetically tractable model system for chemical biology.

Authors:  Shigehiro A Kawashima; Ai Takemoto; Paul Nurse; Tarun M Kapoor
Journal:  Chem Biol       Date:  2012-07-27
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