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Literature DB >> 17715978

Callophycoic acids and callophycols from the Fijian red alga Callophycus serratus.

Amy L Lane¹, Elizabeth P Stout, Mark E Hay, Anne C Prusak, Kenneth Hardcastle, Craig R Fairchild, Scott G Franzblau, Karine Le Roch, Jacques Prudhomme, William Aalbersberg, Julia Kubanek.

Abstract

Callophycoic acids A-H (1-8) and callophycols A and B (9 and 10) were isolated from extracts of the Fijian red alga Callophycus serratus, and identified by NMR, X-ray, and mass spectral analyses. These natural products represent four novel carbon skeletons, providing the first examples of diterpene-benzoic acids and diterpene-phenols in macroalgae. Compounds 1-10 exhibited antibacterial, antimalarial, and anticancer activity, although they are less bioactive than diterpene-benzoate macrolides previously isolated from this red alga.

Entities: Chemical Species

Mesh：

Substances：

Year: 2007 PMID： 17715978 PMCID： PMC3374858 DOI： 10.1021/jo071210y

Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354

18 in total

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3. Bromophycolides C-I from the Fijian red alga Callophycus serratus.

Authors: Julia Kubanek; Anne C Prusak; Terry W Snell; Rachel A Giese; Craig R Fairchild; William Aalbersberg; Mark E Hay
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Authors: M Kuniyoshi; M S Marma; T Higa; G Bernardinelli; C W Jefford
Journal: J Nat Prod Date: 2001-06 Impact factor: 4.050

7. Antineoplastic diterpene-benzoate macrolides from the Fijian red alga Callophycus serratus.

Authors: Julia Kubanek; Anne C Prusak; Terry W Snell; Rachel A Giese; Kenneth I Hardcastle; Craig R Fairchild; William Aalbersberg; Carmen Raventos-Suarez; Mark E Hay
Journal: Org Lett Date: 2005-11-10 Impact factor: 6.005

8. Novel, rapid, and inexpensive cell-based quantification of antimalarial drug efficacy.

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10. Human malaria parasites in continuous culture.

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Authors: E Paige Stout; Serena Cervantes; Jacques Prudhomme; Stefan France; James J La Clair; Karine Le Roch; Julia Kubanek
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4. Iodinated Meroditerpenes from a Red Alga Callophycus sp.

Authors: Serge Lavoie; David Brumley; Troy S Alexander; Christine Jasmin; Franz A Carranza; Kate Nelson; Cassandra L Quave; Julia Kubanek
Journal: J Org Chem Date: 2017-04-13 Impact factor: 4.354

5. Inhibitory effect of a callophycin A derivative on iNOS expression via inhibition of Akt in lipopolysaccharide-stimulated RAW 264.7 cells.

Authors: Eun-Jung Park; Li Shen; Dianqing Sun; John M Pezzuto
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6. Enantiospecific Solvolytic Functionalization of Bromochlorides.

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7. Reactive desorption electrospray ionization mass spectrometry (DESI-MS) of natural products of a marine alga.

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Journal: Anal Bioanal Chem Date: 2009-03-07 Impact factor: 4.142

8. Antimalarial bromophycolides J-Q from the Fijian red alga Callophycus serratus.

Authors: Amy L Lane; E Paige Stout; An-Shen Lin; Jacques Prudhomme; Karine Le Roch; Craig R Fairchild; Scott G Franzblau; Mark E Hay; William Aalbersberg; Julia Kubanek
Journal: J Org Chem Date: 2009-04-03 Impact factor: 4.354

9. Bromophycoic acids: bioactive natural products from a Fijian red alga Callophycus sp.

Authors: Margaret E Teasdale; Tonya L Shearer; Sebastian Engel; Troy S Alexander; Craig R Fairchild; Jacques Prudhomme; Manuel Torres; Karine Le Roch; William Aalbersberg; Mark E Hay; Julia Kubanek
Journal: J Org Chem Date: 2012-09-05 Impact factor: 4.354

10. Seaweed allelopathy against coral: surface distribution of a seaweed secondary metabolite by imaging mass spectrometry.

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