Literature DB >> 19963839

Preliminary 6 month results from the Argus II epiretinal prosthesis feasibility study.

Mark S Humayun1, Jessy D Dorn, Ashish K Ahuja, Avi Caspi, Eugene Filley, Gislin Dagnelie, Joël Salzmann, Arturo Santos, Jacque Duncan, Lyndon daCruz, Saddek Mohand-Said, Dean Eliott, Matthew J McMahon, Robert J Greenberg.   

Abstract

The Argus II 60 channel epiretinal prosthesis has been developed in order to provide partial restoration of vision to subjects blinded from outer retinal degenerative disease. To date the device has been implanted in 21 subjects as part of a feasibility study. In 6 month post-implantation door finding and line tracking orientation and mobility testing, subjects have shown improvements of 86% and 73%, respectively, for system on vs. system off. In high-contrast Square Localization tests using a touch screen monitor 87% of tested subjects performed significantly better with the system on compared with off. These preliminary results show that the Argus II system provides some functional vision to blind subjects.

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Year:  2009        PMID: 19963839      PMCID: PMC3337704          DOI: 10.1109/IEMBS.2009.5332695

Source DB:  PubMed          Journal:  Conf Proc IEEE Eng Med Biol Soc        ISSN: 1557-170X


  5 in total

1.  Retinal prosthesis: an encouraging first decade with major challenges ahead.

Authors:  J F Rizzo; J Wyatt; M Humayun; E de Juan; W Liu; A Chow; R Eckmiller; E Zrenner; T Yagi; G Abrams
Journal:  Ophthalmology       Date:  2001-01       Impact factor: 12.079

2.  Morphometric analysis of macular photoreceptors and ganglion cells in retinas with retinitis pigmentosa.

Authors:  J L Stone; W E Barlow; M S Humayun; E de Juan; A H Milam
Journal:  Arch Ophthalmol       Date:  1992-11

3.  Feasibility study of a retinal prosthesis: spatial vision with a 16-electrode implant.

Authors:  Avi Caspi; Jessy D Dorn; Kelly H McClure; Mark S Humayun; Robert J Greenberg; Matthew J McMahon
Journal:  Arch Ophthalmol       Date:  2009-04

4.  Can subretinal microphotodiodes successfully replace degenerated photoreceptors?

Authors:  E Zrenner; A Stett; S Weiss; R B Aramant; E Guenther; K Kohler; K D Miliczek; M J Seiler; H Haemmerle
Journal:  Vision Res       Date:  1999-07       Impact factor: 1.886

5.  Visual perception elicited by electrical stimulation of retina in blind humans.

Authors:  M S Humayun; E de Juan; G Dagnelie; R J Greenberg; R H Propst; D H Phillips
Journal:  Arch Ophthalmol       Date:  1996-01
  5 in total
  30 in total

1.  Use of the Argus II retinal prosthesis to improve visual guidance of fine hand movements.

Authors:  Michael P Barry; Gislin Dagnelie
Journal:  Invest Ophthalmol Vis Sci       Date:  2012-08-01       Impact factor: 4.799

2.  The effect of waveform asymmetry on perception with epiretinal prostheses.

Authors:  Dorsa Haji Ghaffari; Kathleen E Finn; V Swetha E Jeganathan; Uday Patel; Varalakshmi Wuyyuru; Arup Roy; James D Weiland
Journal:  J Neural Eng       Date:  2020-07-24       Impact factor: 5.379

3.  Performance of photovoltaic arrays in-vivo and characteristics of prosthetic vision in animals with retinal degeneration.

Authors:  Henri Lorach; Georges Goetz; Yossi Mandel; Xin Lei; Ludwig Galambos; Theodore I Kamins; Keith Mathieson; Philip Huie; Roopa Dalal; James S Harris; Daniel Palanker
Journal:  Vision Res       Date:  2014-09-26       Impact factor: 1.886

4.  LiGluR restores visual responses in rodent models of inherited blindness.

Authors:  Natalia Caporale; Kathleen D Kolstad; Trevor Lee; Ivan Tochitsky; Deniz Dalkara; Dirk Trauner; Richard Kramer; Yang Dan; Ehud Y Isacoff; John G Flannery
Journal:  Mol Ther       Date:  2011-05-24       Impact factor: 11.454

5.  Development of surgical techniques for implantation of a wireless intraocular epiretinal retina implant in Göttingen minipigs.

Authors:  Thomas Laube; Claudia Brockmann; Gernot Roessler; Peter Walter; Christine Krueger; Michael Goertz; Susanne Klauke; Norbert Bornfeld
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2011-08-23       Impact factor: 3.117

Review 6.  Retinal implants: emergence of a multidisciplinary field.

Authors:  Gislin Dagnelie
Journal:  Curr Opin Neurol       Date:  2012-02       Impact factor: 5.710

Review 7.  Building the bionic eye: an emerging reality and opportunity.

Authors:  Lotfi B Merabet
Journal:  Prog Brain Res       Date:  2011       Impact factor: 2.453

Review 8.  Encoding visual information in retinal ganglion cells with prosthetic stimulation.

Authors:  Daniel K Freeman; Joseph F Rizzo; Shelley I Fried
Journal:  J Neural Eng       Date:  2011-05-18       Impact factor: 5.379

9.  Holographic display system for restoration of sight to the blind.

Authors:  G A Goetz; Y Mandel; R Manivanh; D V Palanker; T Čižmár
Journal:  J Neural Eng       Date:  2013-09-18       Impact factor: 5.379

Review 10.  [Visual prostheses].

Authors:  P Walter
Journal:  Ophthalmologe       Date:  2016-02       Impact factor: 1.059

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