Literature DB >> 19804764

Enhanced SnapShot: Antibiotic inhibition of protein synthesis II.

Daniel Sohmen1, Joerg M Harms, Frank Schlünzen, Daniel N Wilson.   

Abstract

The translational apparatus is one of the major targets for antibiotics in the bacterial cell. Antibiotics predominantly interact with the functional centers of the ribosome, namely the messenger RNA (mRNA)-transfer RNA (tRNA) decoding region on the 30S subunit, the peptidyltransferase center on the 50S subunit, or the ribosomal exit tunnel through which the nascent polypeptide chain passes during translation. Protein synthesis can be divided into three phases: initiation, elongation, and termination/recycling.

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Year:  2009        PMID： 19804764     DOI： 10.1016/j.cell.2009.08.009

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  10 in total

1.  Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action.

Authors:  Jack A Dunkle; Liqun Xiong; Alexander S Mankin; Jamie H D Cate
Journal:  Proc Natl Acad Sci U S A       Date:  2010-09-27       Impact factor: 11.205

Review 2.  Bacterial Protein Synthesis as a Target for Antibiotic Inhibition.

Authors:  Stefan Arenz; Daniel N Wilson
Journal:  Cold Spring Harb Perspect Med       Date:  2016-09-01       Impact factor: 6.915

3.  Differential effects of thiopeptide and orthosomycin antibiotics on translational GTPases.

Authors:  Aleksandra Mikolajka; Hanqing Liu; Yuanwei Chen; Agata L Starosta; Viter Márquez; Marina Ivanova; Barry S Cooperman; Daniel N Wilson
Journal:  Chem Biol       Date:  2011-05-27

4.  Development and characterization of a Pseudomonas aeruginosa in vitro coupled transcription-translation assay system for evaluation of translation inhibitors.

Authors:  Corey Fyfe; Joyce A Sutcliffe; Trudy H Grossman
Journal:  J Microbiol Methods       Date:  2012-06-05       Impact factor: 2.363

5.  Target- and resistance-based mechanistic studies with TP-434, a novel fluorocycline antibiotic.

Authors:  Trudy H Grossman; Agata L Starosta; Corey Fyfe; William O'Brien; David M Rothstein; Aleksandra Mikolajka; Daniel N Wilson; Joyce A Sutcliffe
Journal:  Antimicrob Agents Chemother       Date:  2012-02-21       Impact factor: 5.191

6.  Enabling technologies in discovery: the 2009 Nobel Prize and its implications in antibiotic design.

Authors:  Yinan Wei; Sylvia Daunert
Journal:  Anal Bioanal Chem       Date:  2010-03       Impact factor: 4.142

Review 7.  Elements of ribosomal drug resistance and specificity.

Authors:  Gregor M Blaha; Yury S Polikanov; Thomas A Steitz
Journal:  Curr Opin Struct Biol       Date:  2012-09-13       Impact factor: 6.809

8.  Control of ribosomal subunit rotation by elongation factor G.

Authors:  Arto Pulk; Jamie H D Cate
Journal:  Science       Date:  2013-06-28       Impact factor: 47.728

9.  Stability of antibiotics in drinking water: An advanced approach towards the impacts of water quality parameters on doxycycline bioavailability.

Authors:  Saber Kotb; Moustafa Ahmed; Dalia Hassan; Esraa Soltan
Journal:  J Adv Vet Anim Res       Date:  2019-09-09

Review 10.  How Ribosomes Translate Cancer.

Authors:  Sergey O Sulima; Isabel J F Hofman; Kim De Keersmaecker; Jonathan D Dinman
Journal:  Cancer Discov       Date:  2017-09-18       Impact factor: 39.397
  10 in total

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