BACKGROUND AND OBJECTIVES: The goal of the current study was to determine whether MRI impacts multidisciplinary treatment planning and if it leads to increased mastectomy rates. METHODS: A retrospective review was conducted of 441 patients treated for breast cancer between January 2005 and May 2008 who underwent breast MRI. Data included number of additional findings and their imaging and pathologic work-up. This was analyzed to determine impact of MRI on treatment planning. RESULTS: Of 441 patients, 45% had > or =1 additional finding on MRI. Of 410 patients with complete records, 29% had changes in the treatment plan, including 36 patients who were initially considered for breast conservation but proceeded directly to mastectomy based on MRI findings of suspected multicentricity. Twenty-three of those patients did not have a biopsy of the MRI lesion, with 87% having unicentric disease on final pathology. Overall, the mastectomy rate was 44%, which was significantly increased compared to patients not undergoing MRI (32%, P < 0.05). CONCLUSIONS: Breast MRI alters the treatment planning for many patients with newly diagnosed breast cancer. Mastectomy rates are increased when MRI results alone direct surgical planning. Biopsy of MRI-identified lesions should be performed to avoid over-treatment.
BACKGROUND AND OBJECTIVES: The goal of the current study was to determine whether MRI impacts multidisciplinary treatment planning and if it leads to increased mastectomy rates. METHODS: A retrospective review was conducted of 441 patients treated for breast cancer between January 2005 and May 2008 who underwent breast MRI. Data included number of additional findings and their imaging and pathologic work-up. This was analyzed to determine impact of MRI on treatment planning. RESULTS: Of 441 patients, 45% had > or =1 additional finding on MRI. Of 410 patients with complete records, 29% had changes in the treatment plan, including 36 patients who were initially considered for breast conservation but proceeded directly to mastectomy based on MRI findings of suspected multicentricity. Twenty-three of those patients did not have a biopsy of the MRI lesion, with 87% having unicentric disease on final pathology. Overall, the mastectomy rate was 44%, which was significantly increased compared to patients not undergoing MRI (32%, P < 0.05). CONCLUSIONS: Breast MRI alters the treatment planning for many patients with newly diagnosed breast cancer. Mastectomy rates are increased when MRI results alone direct surgical planning. Biopsy of MRI-identified lesions should be performed to avoid over-treatment.
Authors: Eline E Deurloo; Johannes L Peterse; Emiel J Th Rutgers; Albert P E Besnard; Sara H Muller; Kenneth G A Gilhuijs Journal: Eur J Cancer Date: 2005-07 Impact factor: 9.162
Authors: Eline E Deurloo; William F A Klein Zeggelink; H Jelle Teertstra; Johannes L Peterse; Emiel J Th Rutgers; Sara H Muller; Harry Bartelink; Kenneth G A Gilhuijs Journal: Eur Radiol Date: 2005-11-19 Impact factor: 5.315
Authors: Federica Pediconi; Carlo Catalano; Simona Padula; Antonella Roselli; Enrica Moriconi; Valeria Dominelli; Anna Maria Pronio; Miles A Kirchin; Roberto Passariello Journal: Breast Cancer Res Treat Date: 2007-01-03 Impact factor: 4.872
Authors: Debbie Saslow; Carla Boetes; Wylie Burke; Steven Harms; Martin O Leach; Constance D Lehman; Elizabeth Morris; Etta Pisano; Mitchell Schnall; Stephen Sener; Robert A Smith; Ellen Warner; Martin Yaffe; Kimberly S Andrews; Christy A Russell Journal: CA Cancer J Clin Date: 2007 Mar-Apr Impact factor: 508.702
Authors: Lawrence J Solin; Susan G Orel; Wei-Ting Hwang; Eleanor E Harris; Mitchell D Schnall Journal: J Clin Oncol Date: 2008-01-20 Impact factor: 44.544
Authors: Stephen R Grobmyer; Vincent E Mortellaro; Julia Marshall; Giselle Moore Higgs; Steven N Hochwald; Nancy P Mendenhall; Edward M Copeland; William G Cance Journal: J Am Coll Surg Date: 2008-03-17 Impact factor: 6.113
Authors: Constance D Lehman; Constantine Gatsonis; Christiane K Kuhl; R Edward Hendrick; Etta D Pisano; Lucy Hanna; Sue Peacock; Stanley F Smazal; Daniel D Maki; Thomas B Julian; Elizabeth R DePeri; David A Bluemke; Mitchell D Schnall Journal: N Engl J Med Date: 2007-03-28 Impact factor: 91.245
Authors: Wendie A Berg; Kathleen S Madsen; Kathy Schilling; Marie Tartar; Etta D Pisano; Linda Hovanessian Larsen; Deepa Narayanan; Al Ozonoff; Joel P Miller; Judith E Kalinyak Journal: Radiology Date: 2010-11-12 Impact factor: 11.105
Authors: María Nieves Plana; Carmen Carreira; Alfonso Muriel; Miguel Chiva; Víctor Abraira; Jose Ignacio Emparanza; Xavier Bonfill; Javier Zamora Journal: Eur Radiol Date: 2011-08-17 Impact factor: 5.315
Authors: Jens Hachenberg; Christian Eichler; Lena Steinkasserer; Wolfram Malter; Fabinshy Thangarajah; Mathias Warm; Axel Gossmann; Markus Brod; Caroline Pahmeyer Journal: In Vivo Date: 2022 Sep-Oct Impact factor: 2.406
Authors: Richard G Abramson; Lori R Arlinghaus; Jared A Weis; Xia Li; Adrienne N Dula; Eduard Y Chekmenev; Seth A Smith; Michael I Miga; Vandana G Abramson; Thomas E Yankeelov Journal: Breast Cancer (Dove Med Press) Date: 2012-10
Authors: Kandace P McGuire; E Shelley Hwang; Alan Cantor; Mehra Golshan; Funda Meric-Bernstam; Janet K Horton; Rita Nanda; Keith D Amos; Andres Forero; Cliff A Hudis; Ingrid Meszoely; Jennifer F De Los Santos Journal: Ann Surg Oncol Date: 2014-07-25 Impact factor: 5.344
Authors: Laura S Gold; Diana S M Buist; Elizabeth T Loggers; Ruth Etzioni; Larry Kessler; Scott D Ramsey; Sean D Sullivan Journal: J Oncol Pract Date: 2013-05-28 Impact factor: 3.840
Authors: Elizabeth Trice Loggers; Diana S M Buist; Laura S Gold; Steven Zeliadt; Rachel Hunter Merrill; Ruth Etzioni; Scott D Ramsey; Sean D Sullivan; Larry Kessler Journal: Int J Breast Cancer Date: 2016-07-25