Literature DB >> 19673228

An investigation of signal performance enhancements achieved through innovative pixel design across several generations of indirect detection, active matrix, flat-panel arrays.

Larry E Antonuk1, Qihua Zhao, Youcef El-Mohri, Hong Du, Yi Wang, Robert A Street, Jackson Ho, Richard Weisfield, William Yao.   

Abstract

Active matrix flat-panel imager (AMFPI) technology is being employed for an increasing variety of imaging applications. An important element in the adoption of this technology has been significant ongoing improvements in optical signal collection achieved through innovations in indirect detection array pixel design. Such improvements have a particularly beneficial effect on performance in applications involving low exposures and/or high spatial frequencies, where detective quantum efficiency is strongly reduced due to the relatively high level of additive electronic noise compared to signal levels of AMFPI devices. In this article, an examination of various signal properties, as determined through measurements and calculations related to novel array designs, is reported in the context of the evolution of AMFPI pixel design. For these studies, dark, optical, and radiation signal measurements were performed on prototype imagers incorporating a variety of increasingly sophisticated array designs, with pixel pitches ranging from 75 to 127 microm. For each design, detailed measurements of fundamental pixel-level properties conducted under radiographic and fluoroscopic operating conditions are reported and the results are compared. A series of 127 microm pitch arrays employing discrete photodiodes culminated in a novel design providing an optical fill factor of approximately 80% (thereby assuring improved x-ray sensitivity), and demonstrating low dark current, very low charge trapping and charge release, and a large range of linear signal response. In two of the designs having 75 and 90 microm pitches, a novel continuous photodiode structure was found to provide fill factors that approach the theoretical maximum of 100%. Both sets of novel designs achieved large fill factors by employing architectures in which some, or all of the photodiode structure was elevated above the plane of the pixel addressing transistor. Generally, enhancement of the fill factor in either discrete or continuous photodiode arrays was observed to result in no degradation in MTF due to charge sharing between pixels. While the continuous designs exhibited relatively high levels of charge trapping and release, as well as shorter ranges of linearity, it is possible that these behaviors can be addressed through further refinements to pixel design. Both the continuous and the most recent discrete photodiode designs accommodate more sophisticated pixel circuitry than is present on conventional AMFPIs--such as a pixel clamp circuit, which is demonstrated to limit signal saturation under conditions corresponding to high exposures. It is anticipated that photodiode structures such as the ones reported in this study will enable the development of even more complex pixel circuitry, such as pixel-level amplifiers, that will lead to further significant improvements in imager performance.

Mesh:

Year:  2009        PMID: 19673228      PMCID: PMC2807886          DOI: 10.1118/1.3049602

Source DB:  PubMed          Journal:  Med Phys        ISSN: 0094-2405            Impact factor:   4.071


  12 in total

1.  A ghost story: spatio-temporal response characteristics of an indirect-detection flat-panel imager.

Authors:  J H Siewerdsen; D A Jaffray
Journal:  Med Phys       Date:  1999-08       Impact factor: 4.071

2.  Strategies to improve the signal and noise performance of active matrix, flat-panel imagers for diagnostic x-ray applications.

Authors:  L E Antonuk; K W Jee; Y El-Mohri; M Maolinbay; S Nassif; X Rong; Q Zhao; J H Siewerdsen; R A Street; K S Shah
Journal:  Med Phys       Date:  2000-02       Impact factor: 4.071

3.  Additive noise properties of active matrix flat-panel imagers.

Authors:  M Maolinbay; Y El-Mohri; L E Antonuk; K W Jee; S Nassif; X Rong; Q Zhao
Journal:  Med Phys       Date:  2000-08       Impact factor: 4.071

4.  Performance of a high fill factor, indirect detection prototype flat-panel imager for mammography.

Authors:  Youcef El-Mohri; Larry E Antonuk; Qihua Zhao; Yi Wang; Yixin Li; Hong Du; Amit Sawant
Journal:  Med Phys       Date:  2007-01       Impact factor: 4.071

5.  Investigation of the signal behavior at diagnostic energies of prototype, direct detection, active matrix, flat-panel imagers incorporating polycrystalline HgI2.

Authors:  Hong Du; Larry E Antonuk; Youcef El-Mohri; Qihua Zhao; Zhong Su; Jin Yamamoto; Yi Wang
Journal:  Phys Med Biol       Date:  2008-02-14       Impact factor: 3.609

6.  A simple method for determining the modulation transfer function in digital radiography.

Authors:  H Fujita; D Y Tsai; T Itoh; K Doi; J Morishita; K Ueda; A Ohtsuka
Journal:  IEEE Trans Med Imaging       Date:  1992       Impact factor: 10.048

7.  Initial performance evaluation of an indirect-detection, active matrix flat-panel imager (AMFPI) prototype for megavoltage imaging.

Authors:  L E Antonuk; Y El-Mohri; W Huang; K W Jee; J H Siewerdsen; M Maolinbay; V E Scarpine; H Sandler; J Yorkston
Journal:  Int J Radiat Oncol Biol Phys       Date:  1998-09-01       Impact factor: 7.038

8.  Digital radiology using active matrix readout of amorphous selenium: theoretical analysis of detective quantum efficiency.

Authors:  W Zhao; J A Rowlands
Journal:  Med Phys       Date:  1997-12       Impact factor: 4.071

9.  Empirical investigation of the signal performance of a high-resolution, indirect detection, active matrix flat-panel imager (AMFPI) for fluoroscopic and radiographic operation.

Authors:  L E Antonuk; Y El-Mohri; J H Siewerdsen; J Yorkston; W Huang; V E Scarpine; R A Street
Journal:  Med Phys       Date:  1997-01       Impact factor: 4.071

10.  Active pixel imagers incorporating pixel-level amplifiers based on polycrystalline-silicon thin-film transistors.

Authors:  Youcef El-Mohri; Larry E Antonuk; Martin Koniczek; Qihua Zhao; Yixin Li; Robert A Street; Jeng-Ping Lu
Journal:  Med Phys       Date:  2009-07       Impact factor: 4.071

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  7 in total

1.  A theoretical and experimental evaluation of the microangiographic fluoroscope: A high-resolution region-of-interest x-ray imager.

Authors:  Amit Jain; D R Bednarek; Ciprian Ionita; S Rudin
Journal:  Med Phys       Date:  2011-07       Impact factor: 4.071

2.  Optimization of the performance of segmented scintillators for radiotherapy imaging through novel binning techniques.

Authors:  Youcef El-Mohri; Larry E Antonuk; Richard B Choroszucha; Qihua Zhao; Hao Jiang; Langechuan Liu
Journal:  Phys Med Biol       Date:  2014-02-03       Impact factor: 3.609

3.  Theoretical investigation of the noise performance of active pixel imaging arrays based on polycrystalline silicon thin film transistors.

Authors:  Martin Koniczek; Larry E Antonuk; Youcef El-Mohri; Albert K Liang; Qihua Zhao
Journal:  Med Phys       Date:  2017-05-22       Impact factor: 4.071

4.  Low-dose megavoltage cone-beam CT imaging using thick, segmented scintillators.

Authors:  Youcef El-Mohri; Larry E Antonuk; Qihua Zhao; Richard B Choroszucha; Hao Jiang; Langechuan Liu
Journal:  Phys Med Biol       Date:  2011-02-16       Impact factor: 3.609

5.  Scintillator high-gain avalanche rushing photoconductor active-matrix flat panel imager: zero-spatial frequency x-ray imaging properties of the solid-state SHARP sensor structure.

Authors:  M Wronski; W Zhao; K Tanioka; G Decrescenzo; J A Rowlands
Journal:  Med Phys       Date:  2012-11       Impact factor: 4.071

6.  Active pixel imagers incorporating pixel-level amplifiers based on polycrystalline-silicon thin-film transistors.

Authors:  Youcef El-Mohri; Larry E Antonuk; Martin Koniczek; Qihua Zhao; Yixin Li; Robert A Street; Jeng-Ping Lu
Journal:  Med Phys       Date:  2009-07       Impact factor: 4.071

Review 7.  Amorphous and polycrystalline photoconductors for direct conversion flat panel x-ray image sensors.

Authors:  Safa Kasap; Joel B Frey; George Belev; Olivier Tousignant; Habib Mani; Jonathan Greenspan; Luc Laperriere; Oleksandr Bubon; Alla Reznik; Giovanni DeCrescenzo; Karim S Karim; John A Rowlands
Journal:  Sensors (Basel)       Date:  2011-05-09       Impact factor: 3.576

  7 in total

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