| Literature DB >> 19444841 |
James C Delaney1, Jianmin Gao, Haibo Liu, Nidhi Shrivastav, John M Essigmann, Eric T Kool.
Abstract
Supersize me! Size-expanded DNA bases (xDNA) are able to encode natural DNA sequences in replication. In vitro experiments with a DNA polymerase show nucleotide incorporation opposite the xDNA bases with correct pairing. In vivo experiments using E. coli show that two xDNA bases (xA and xC, see picture) encode the correct replication partners.Entities:
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Year: 2009 PMID: 19444841 PMCID: PMC3434874 DOI: 10.1002/anie.200805683
Source DB: PubMed Journal: Angew Chem Int Ed Engl ISSN: 1433-7851 Impact factor: 15.336