Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Non-natural nucleic acids for synthetic biology.

Literature DB >> 19879178

Non-natural nucleic acids for synthetic biology.

Abstract

Genetic manipulation is an important facet of synthetic biology but can be complicated by undesired nuclease degradation. Incorporating non-natural nucleic acids into a gene could convey resistance to nucleases and promote expression. The compatibility of non-natural nucleosides with polymerases is reviewed with a focus on results from the past two years. Details are provided about how the different systems could be useful in synthetic biology.

Entities: CellLine Chemical Disease Gene Mutation Species

Mesh：

Substances：

Year: 2009 PMID： 19879178 PMCID： PMC3152792 DOI： 10.1016/j.cbpa.2009.09.030

Source DB: PubMed Journal: Curr Opin Chem Biol ISSN： 1367-5931 Impact factor: 8.822

106 in total

Review 1. LNA: a versatile tool for therapeutics and genomics.

Authors: Michael Petersen; Jesper Wengel
Journal: Trends Biotechnol Date: 2003-02 Impact factor: 19.536

2. Synthetic biology.

Authors: A Michael Sismour; Steven A Benner
Journal: Expert Opin Biol Ther Date: 2005-11 Impact factor: 4.388

3. Light-directed synthesis of peptide nucleic acids (PNAs) chips.

Authors: Zheng-Chun Liu; Dong-Sik Shin; Mohammadreza Shokouhimehr; Kook-Nyung Lee; Byung-Wook Yoo; Yong-Kweon Kim; Yoon-Sik Lee
Journal: Biosens Bioelectron Date: 2007-01-19 Impact factor: 10.618

4. A heterogeneous PNA-based SERS method for DNA detection.

Authors: Laura Fabris; Mark Dante; Gary Braun; Seung Joon Lee; Norbert O Reich; Martin Moskovits; Thuc-Quyen Nguyen; Guillermo C Bazan
Journal: J Am Chem Soc Date: 2007-04-24 Impact factor: 15.419

5. Colorimetric detection of anthrax DNA with a Peptide nucleic acid sandwich-hybridization assay.

Authors: Ning Zhang; Daniel H Appella
Journal: J Am Chem Soc Date: 2007-06-15 Impact factor: 15.419

Review 6. Redesigning the architecture of the base pair: toward biochemical and biological function of new genetic sets.

Authors: Andrew T Krueger; Eric T Kool
Journal: Chem Biol Date: 2009-03-27

7. Parallel nucleic acid recognition by the LNA (locked nucleic acid) stereoisomers beta-L-LNA and alpha-D-LNA; studies in the mirror image world.

Authors: Nanna K Christensen; Torsten Bryld; Mads D Sørensen; Khalil Arar; Jesper Wengel; Poul Nielsen
Journal: Chem Commun (Camb) Date: 2003-12-19 Impact factor: 6.222

Review 8. Synthetic biology.

Authors: Steven A Benner; A Michael Sismour
Journal: Nat Rev Genet Date: 2005-07 Impact factor: 53.242

9. Enzymatic primer-extension with glycerol-nucleoside triphosphates on DNA templates.

Authors: Jesse J Chen; Ching-Hsuan Tsai; Xin Cai; Allen T Horhota; Larry W McLaughlin; Jack W Szostak
Journal: PLoS One Date: 2009-03-23 Impact factor: 3.240

10. Nucleoside alpha-thiotriphosphates, polymerases and the exonuclease III analysis of oligonucleotides containing phosphorothioate linkages.

Authors: Zunyi Yang; A Michael Sismour; Steven A Benner
Journal: Nucleic Acids Res Date: 2007-04-22 Impact factor: 16.971

21 in total

1. Site-specific fluorescent probing of RNA molecules by unnatural base-pair transcription for local structural conformation analysis.

Authors: Yasushi Hikida; Michiko Kimoto; Shigeyuki Yokoyama; Ichiro Hirao
Journal: Nat Protoc Date: 2010-06-24 Impact factor: 13.491

Non-natural nucleic acids for synthetic biology.

Review 1. LNA: a versatile tool for therapeutics and genomics.

2. Synthetic biology.

3. Light-directed synthesis of peptide nucleic acids (PNAs) chips.

4. A heterogeneous PNA-based SERS method for DNA detection.

5. Colorimetric detection of anthrax DNA with a Peptide nucleic acid sandwich-hybridization assay.

Review 6. Redesigning the architecture of the base pair: toward biochemical and biological function of new genetic sets.

7. Parallel nucleic acid recognition by the LNA (locked nucleic acid) stereoisomers beta-L-LNA and alpha-D-LNA; studies in the mirror image world.

Review 8. Synthetic biology.

9. Enzymatic primer-extension with glycerol-nucleoside triphosphates on DNA templates.

10. Nucleoside alpha-thiotriphosphates, polymerases and the exonuclease III analysis of oligonucleotides containing phosphorothioate linkages.

1. Site-specific fluorescent probing of RNA molecules by unnatural base-pair transcription for local structural conformation analysis.

2. Synthesis of Bifacial Peptide Nucleic Acids with Diketopiperazine Backbones.

3. Impact of bPNA Backbone Structural Constraints and Composition on Triplex Hybridization with DNA.

4. Directed evolution: overcoming biology's limitations.

Review 5. Synthetic biology: putting synthesis into biology.

6. Enhanced Triplex Hybridization of DNA and RNA via Syndiotactic Side Chain Presentation in Minimal bPNAs.

Review 7. Synthetic Biology: A Bridge between Artificial and Natural Cells.

Review 8. RNA modularity for synthetic biology.

Review 9. The structural diversity of artificial genetic polymers.

10. DNA-based control of protein activity.