Literature DB >> 1928101

D19S51 is closely linked with and maps distal to the myotonic dystrophy locus on 19q.

C Tsilfidis1, A E MacKenzie, G Shutler, S Leblond, J Bailly, K Johnson, R Williamson, J Siegel-Bartelt, R G Korneluk, P Shelbourne.   

Abstract

Recent genetic linkage studies have mapped the myotonic dystrophy (DM) locus to 19q13.3. All closely linked DM markers identified to date have been located on the centromeric side of the disease locus, with a relatively large genetic interval (9 cM) observed between the nearest distal marker and DM. We show here that the recently described marker p134C is tightly linked to DM (peak lod score 35.8 at peak recombination fraction .006) and confirm the previous suggestion that the p134C locus, D19S51 maps distal to the disease locus. D19S51 and the closest proximal flanking loci, ERCC1 and D19S115 (pE0.8), define a small genetic interval of less than 2 cM that contains the DM locus.

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Year:  1991        PMID： 1928101      PMCID： PMC1683251     

Source DB:  PubMed          Journal:  Am J Hum Genet        ISSN： 0002-9297            Impact factor:   11.025


  14 in total

1.  A multipoint linkage map around the locus for myotonic dystrophy on chromosome 19.

Authors:  H G Brunner; H Smeets; H M Lambermon; M Coerwinkel-Driessen; B A van Oost; B Wieringa; H H Ropers
Journal:  Genomics       Date:  1989-10       Impact factor: 5.736

2.  Definition of subchromosomal intervals around the myotonic dystrophy gene region at 19q.

Authors:  D Schonk; M Coerwinkel-Driessen; I van Dalen; F Oerlemans; B Smeets; J Schepens; T Hulsebos; D Cockburn; Y Boyd; M Davis
Journal:  Genomics       Date:  1989-04       Impact factor: 5.736

3.  Criteria for establishing the validity of genetic recombination in myotonic dystrophy.

Authors:  R C Griggs; D S Wood
Journal:  Neurology       Date:  1989-03       Impact factor: 9.910

4.  A reordering of human chromosome 19 long-arm DNA markers and identification of markers flanking the myotonic dystrophy locus.

Authors:  R G Korneluk; A E MacKenzie; Y Nakamura; I Dubé; P Jacob; A G Hunter
Journal:  Genomics       Date:  1989-10       Impact factor: 5.736

5.  Physical and genetic mapping of a novel chromosome 19 ERCC1 marker showing close linkage with myotonic dystrophy.

Authors:  G Shutler; A E MacKenzie; H Brunner; B Wieringa; P de Jong; F P Lohman; S Leblond; J Bailly; R G Korneluk
Journal:  Genomics       Date:  1991-03       Impact factor: 5.736

6.  Recombination events that locate myotonic dystrophy distal to APOC2 on 19q.

Authors:  K Johnson; P Shelbourne; J Davies; J Buxton; E Nimmo; M Anvret; M Bonduelle; B Williamson; M L Savontaus
Journal:  Genomics       Date:  1989-11       Impact factor: 5.736

7.  Linkage analysis of the apolipoprotein C2 gene and myotonic dystrophy on human chromosome 19 reveals linkage disequilibrium in a French-Canadian population.

Authors:  A E MacKenzie; H L MacLeod; A G Hunter; R G Korneluk
Journal:  Am J Hum Genet       Date:  1989-01       Impact factor: 11.025

8.  Multilocus linkage analysis in humans: detection of linkage and estimation of recombination.

Authors:  G M Lathrop; J M Lalouel; C Julier; J Ott
Journal:  Am J Hum Genet       Date:  1985-05       Impact factor: 11.025

9.  A long-range restriction map of the human chromosome 19q13 region: close physical linkage between CKMM and the ERCC1 and ERCC2 genes.

Authors:  H Smeets; L Bachinski; M Coerwinkel; J Schepens; J Hoeijmakers; M van Duin; K H Grzeschik; C A Weber; P de Jong; M J Siciliano
Journal:  Am J Hum Genet       Date:  1990-03       Impact factor: 11.025

10.  Human creatine kinase genes on chromosomes 15 and 19, and proximity of the gene for the muscle form to the genes for apolipoprotein C2 and excision repair.

Authors:  R L Stallings; E Olson; A W Strauss; L H Thompson; L L Bachinski; M J Siciliano
Journal:  Am J Hum Genet       Date:  1988-08       Impact factor: 11.025
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  1 in total

1.  French myotonic dystrophy families show expansion of a CTG repeat in complete linkage disequilibrium with an intragenic 1 kb insertion.

Authors:  C Lavedan; H Hofmann-Radvanyi; C Boileau; C Bonaïti-Pellié; D Savoy; P Shelbourne; C Duros; J P Rabes; I Dehaupas; S Luce
Journal:  J Med Genet       Date:  1994-01       Impact factor: 6.318
  1 in total

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