Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 A preliminary neutron crystallographic study of an A-DNA crystal.

Literature DB >> 19255472

A preliminary neutron crystallographic study of an A-DNA crystal.

Ricardo M F Leal¹, Susana C M Teixeira, Matthew P Blakeley, Edward P Mitchell, V Trevor Forsyth.
1. ESRF, Grenoble, France.

Abstract

The LADI-III diffractometer at the Institut Laue-Langevin has been used to carry out a preliminary neutron crystallographic study of the self-complementary DNA oligonucleotide d(AGGGGCCCCT)(2) in the A conformation. The results demonstrate the viability of a full neutron crystallographic analysis with the aim of providing enhanced information on the ion-water networks that are known to be important in stabilizing A-DNA. This is the first account of a single-crystal neutron diffraction study of A-DNA. The study was carried out with the smallest crystal used to date for a neutron crystallographic study of a biological macromolecule.

Entities: Chemical

Mesh：

Substances：

Year: 2009 PMID： 19255472 PMCID： PMC2650452 DOI： 10.1107/S1744309109002668

Source DB: PubMed Journal: Acta Crystallogr Sect F Struct Biol Cryst Commun ISSN： 1744-3091

35 in total

1. A crystallographic map of the transition from B-DNA to A-DNA.

Authors: J M Vargason; K Henderson; P S Ho
Journal: Proc Natl Acad Sci U S A Date: 2001-06-05 Impact factor: 11.205

2. Comparison of hydrogen determination with X-ray and neutron crystallography in a human aldose reductase-inhibitor complex.

Authors: M P Blakeley; A Mitschler; I Hazemann; F Meilleur; D A A Myles; A Podjarny
Journal: Eur Biophys J Date: 2006-04-19 Impact factor: 1.733

3. A preliminary neutron diffraction study of rasburicase, a recombinant urate oxidase enzyme, complexed with 8-azaxanthin.

Authors: Monika Budayova-Spano; Françoise Bonneté; Natalie Ferté; Mohamed El Hajji; Flora Meilleur; Matthew Paul Blakeley; Bertrand Castro
Journal: Acta Crystallogr Sect F Struct Biol Cryst Commun Date: 2006-02-28

4. Quantum model of catalysis based on a mobile proton revealed by subatomic x-ray and neutron diffraction studies of h-aldose reductase.

Authors: Matthew P Blakeley; Federico Ruiz; Raul Cachau; Isabelle Hazemann; Flora Meilleur; Andre Mitschler; Stephan Ginell; Pavel Afonine; Oscar N Ventura; Alexandra Cousido-Siah; Michael Haertlein; Andrzej Joachimiak; Dean Myles; Alberto Podjarny
Journal: Proc Natl Acad Sci U S A Date: 2008-02-04 Impact factor: 11.205

5. Time-resolved X-ray diffraction studies of the B in equilibrium D structural transition in the DNA double helix.

Authors: A Mahendrasingam; V T Forsyth; R Hussain; R J Greenall; W J Pigram; W Fuller
Journal: Science Date: 1986-07-11 Impact factor: 47.728

6. Crystal structure of an RNA duplex r(G GCGC CC)2 with non-adjacent G*U base pairs.

Authors: K Shi; M Wahl; M Sundaralingam
Journal: Nucleic Acids Res Date: 1999-05-15 Impact factor: 16.971

7. Targeting DNA-binding drugs to sequence-specific transcription factor.DNA complexes. Differential effects of intercalating and minor groove binding drugs.

Authors: J J Welch; F J Rauscher; T A Beerman
Journal: J Biol Chem Date: 1994-12-09 Impact factor: 5.157

A preliminary neutron crystallographic study of an A-DNA crystal.

1. A crystallographic map of the transition from B-DNA to A-DNA.

2. Comparison of hydrogen determination with X-ray and neutron crystallography in a human aldose reductase-inhibitor complex.

3. A preliminary neutron diffraction study of rasburicase, a recombinant urate oxidase enzyme, complexed with 8-azaxanthin.

4. Quantum model of catalysis based on a mobile proton revealed by subatomic x-ray and neutron diffraction studies of h-aldose reductase.

5. Time-resolved X-ray diffraction studies of the B in equilibrium D structural transition in the DNA double helix.

6. Crystal structure of an RNA duplex r(G GCGC CC)2 with non-adjacent G*U base pairs.

7. Targeting DNA-binding drugs to sequence-specific transcription factor.DNA complexes. Differential effects of intercalating and minor groove binding drugs.

8. X-ray, neutron and NMR studies of the catalytic mechanism of aspartic proteinases.

Review 9. Water-DNA interactions as studied by X-ray and neutron fibre diffraction.

Review 10. Neutron crystallography: opportunities, challenges, and limitations.

1. Preliminary neutron crystallographic study of human transthyretin.

2. Seeing the chemistry in biology with neutron crystallography.

3. Experimental procedure for the characterization of radiation damage in macromolecular crystals.