Literature DB >> 19018472

Colorectal surgeons and biomedical scientists improve lymph node harvest in colorectal cancer.

A Shaw1, E E Collins, A Fakis, P Patel, D Semeraro, J N Lund.   

Abstract

BACKGROUND: The aim of this study was to review lymph node retrieval from colorectal cancer resections.
METHODS: We examined consecutive, single colorectal cancers excised between September 1999 and February 2007. Data gathered included patient age and gender, cancer location, total number of lymph nodes and involved lymph nodes identified. The speciality of the operating surgeon was recorded. Whether a pathologist or biomedical scientist was responsible for harvesting lymph nodes from the resected specimen was also noted.
RESULTS: A total of 1,194 patients were identified. Increased numbers of lymph nodes identified was associated with increased lymph node positivity (p<0.001, r=0.121). Biomedical scientists identified more lymph nodes (median 15, range 12-20) within specimens than consultant pathologists (median 10, range 7-13; p<0.001). Colorectal surgeons removed more lymph nodes (median 11, range 7-15) than non-colorectal surgeons (median 9, range 7-14; p=0.002).
CONCLUSIONS: There was a significant increase in lymph node harvesting over time and this correlated with lymph node positivity. Lymph node harvest was significantly higher when the resection was performed by a colorectal surgeon and when the specimen was examined by a biomedical scientist. For accurate staging and consequent correct planning of adjuvant treatment and prognosis, resections should be performed by a colorectal surgeon and the lymph nodes harvested by a biomedical scientist.

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Mesh:

Year:  2008        PMID: 19018472     DOI: 10.1007/s10151-008-0438-2

Source DB:  PubMed          Journal:  Tech Coloproctol        ISSN: 1123-6337            Impact factor:   3.781


  28 in total

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2.  Clinicopathological staging for colorectal cancer: an International Documentation System (IDS) and an International Comprehensive Anatomical Terminology (ICAT).

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3.  Colon and rectal surgery: a true subspecialty.

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Journal:  Dis Colon Rectum       Date:  1998-01       Impact factor: 4.585

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Journal:  Dis Colon Rectum       Date:  1988-03       Impact factor: 4.585

5.  A national study on lymph node retrieval in resectional surgery for colorectal cancer.

Authors:  Paris P Tekkis; Jason J Smith; Alexander G Heriot; Ara W Darzi; Michael R Thompson; Jeffrey D Stamatakis
Journal:  Dis Colon Rectum       Date:  2006-11       Impact factor: 4.585

6.  Surgeon-related factors and outcome in rectal cancer.

Authors:  G A Porter; C L Soskolne; W W Yakimets; S C Newman
Journal:  Ann Surg       Date:  1998-02       Impact factor: 12.969

7.  Is fellowship training in alimentary tract surgery necessary?

Authors:  J L Cameron
Journal:  Am J Surg       Date:  1993-01       Impact factor: 2.565

8.  Lymph node recovery from colorectal resection specimens removed for adenocarcinoma. Trends over time and a recommendation for a minimum number of lymph nodes to be recovered.

Authors:  N S Goldstein; W Sanford; M Coffey; L J Layfield
Journal:  Am J Clin Pathol       Date:  1996-08       Impact factor: 2.493

9.  Number of nodes examined and staging accuracy in colorectal carcinoma.

Authors:  J H Wong; R Severino; M B Honnebier; P Tom; T S Namiki
Journal:  J Clin Oncol       Date:  1999-09       Impact factor: 44.544

10.  Local recurrence following 'curative' surgery for large bowel cancer: I. The overall picture.

Authors:  R K Phillips; R Hittinger; L Blesovsky; J S Fry; L P Fielding
Journal:  Br J Surg       Date:  1984-01       Impact factor: 6.939

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  7 in total

1.  Robotic Surgery for Rectal Cancer: Hype or Hope? (Indian Experience).

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Review 2.  Pathologist's assistant (PathA) and his/her role in the surgical pathology department: a systematic review and a narrative synthesis.

Authors:  M Bortesi; V Martino; M Marchetti; A Cavazza; G Gardini; E Zanetti; M C Bassi; L Ghirotto; M Costantini; Simonetta Piana
Journal:  Virchows Arch       Date:  2018-01-29       Impact factor: 4.064

3.  The impact of age on quality measure adherence in colon cancer.

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Journal:  J Am Coll Surg       Date:  2011-05-20       Impact factor: 6.113

Review 4.  There is no difference in outcome between laparoscopic and open surgery for rectal cancer: a systematic review and meta-analysis on short- and long-term oncologic outcomes.

Authors:  M Pędziwiatr; P Małczak; M Mizera; J Witowski; G Torbicz; P Major; M Pisarska; M Wysocki; A Budzyński
Journal:  Tech Coloproctol       Date:  2017-08-09       Impact factor: 3.781

Review 5.  Colorectal cancer and lymph nodes: the obsession with the number 12.

Authors:  Giovanni Li Destri; Isidoro Di Carlo; Roberto Scilletta; Beniamino Scilletta; Stefano Puleo
Journal:  World J Gastroenterol       Date:  2014-02-28       Impact factor: 5.742

6.  Lymph node harvest in colon cancer: influence of microsatellite instability and proximal tumor location.

Authors:  Kjetil Søreide; Bjørn Steinar Nedrebø; Jon Arne Søreide; Aida Slewa; Hartwig Kørner
Journal:  World J Surg       Date:  2009-12       Impact factor: 3.352

Review 7.  Assessment of lymph node involvement in colorectal cancer.

Authors:  Mark L H Ong; John B Schofield
Journal:  World J Gastrointest Surg       Date:  2016-03-27
  7 in total

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