Literature DB >> 18842048

A diazirine-based nucleoside analogue for efficient DNA interstrand photocross-linking.

Zhihai Qiu1, Lianghua Lu, Xing Jian, Chuan He.   

Abstract

A diazirine-based nucleoside analogue (DBN) efficiently forms DNA interstand cross-linking under near-UV irradiation. This new base analogue may find broad applications in biotechnology and phototherapy.

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Year:  2008        PMID: 18842048      PMCID: PMC2945524          DOI: 10.1021/ja805445j

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN: 0002-7863            Impact factor:   15.419


  22 in total

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9.  Synthesis and biophysical studies of short oligodeoxynucleotides with novel modifications: a possible approach to the problem of mixed base oligodeoxynucleotide synthesis.

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10.  3-Trifluoromethyl-3-phenyldiazirine. A new carbene generating group for photolabeling reagents.

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2.  Bioorthogonal labeling of 5-hydroxymethylcytosine in genomic DNA and diazirine-based DNA photo-cross-linking probes.

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8.  A versatile method for the UVA-induced cross-linking of acetophenone- or benzophenone-functionalized DNA.

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10.  Synthesis of cross-linked DNA containing oxidized abasic site analogues.

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