Literature DB >> 18823891

Validation of a liquid chromatography-tandem mass spectrometry method to enable quantification of 3-iodothyronamine from serum.

Andrea E DeBarber1, Travis Geraci, Vincent P Colasurdo, Sarah A Hackenmueller, Thomas S Scanlan.   

Abstract

There is great interest lately in the availability of analytical methods for quantification of 3-iodothyronamine from blood and tissues. To date, no validated method for determination of 3-iodothyronamine from biological matrices has been described. Detailed in this report is an LC-MS/MS method that permits accurate and reproducible quantification of pharmacological concentrations of 3-iodothyronamine from rat serum, with a 0.0008 M lower limit of quantification. Endogenous 3-iodothyronamine was observed from rodent and human serum (0.2 mL) at the method limit of detection. In summary, the LC-MS/MS method enables quantification of circulating 3-iodothyronamine to allow examination of a relationship with biological activity.

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Year:  2008        PMID： 18823891      PMCID： PMC3609708          DOI： 10.1016/j.chroma.2008.09.022

Source DB:  PubMed          Journal:  J Chromatogr A        ISSN： 0021-9673            Impact factor:   4.759


  15 in total

1.  Development and evaluation of a reference measurement procedure for the determination of total 3,3',5-triiodothyronine in human serum using isotope-dilution liquid chromatography-tandem mass spectrometry.

Authors:  Susan S-C Tai; David M Bunk; Edward White; Michael J Welch
Journal:  Anal Chem       Date:  2004-09-01       Impact factor: 6.986

2.  Assessing analytical specificity in quantitative analysis using tandem mass spectrometry.

Authors:  Mark M Kushnir; Alan L Rockwood; Gordon J Nelson; Bingfang Yue; Francis M Urry
Journal:  Clin Biochem       Date:  2005-04       Impact factor: 3.281

3.  Thyronamines are substrates for human liver sulfotransferases.

Authors:  C A Pietsch; T S Scanlan; R J Anderson
Journal:  Endocrinology       Date:  2007-01-04       Impact factor: 4.736

4.  The measurement of free thyroxine by isotope dilution tandem mass spectrometry.

Authors:  Steven J Soldin; Nadia Soukhova; Natasa Janicic; Jacqueline Jonklaas; Offie P Soldin
Journal:  Clin Chim Acta       Date:  2005-04-12       Impact factor: 3.786

5.  Trace amine-associated receptor agonists: synthesis and evaluation of thyronamines and related analogues.

Authors:  Matthew E Hart; Katherine L Suchland; Motonori Miyakawa; James R Bunzow; David K Grandy; Thomas S Scanlan
Journal:  J Med Chem       Date:  2006-02-09       Impact factor: 7.446

6.  Candidate reference method for total thyroxine in human serum: use of isotope-dilution liquid chromatography-mass spectrometry with electrospray ionization.

Authors:  Susan S-C Tai; Lorna T Sniegoski; Michael J Welch
Journal:  Clin Chem       Date:  2002       Impact factor: 8.327

7.  Cardiac effects of 3-iodothyronamine: a new aminergic system modulating cardiac function.

Authors:  Grazia Chiellini; Sabina Frascarelli; Sandra Ghelardoni; Vittoria Carnicelli; Sandra C Tobias; Andrea DeBarber; Simona Brogioni; Simonetta Ronca-Testoni; Elisabetta Cerbai; David K Grandy; Thomas S Scanlan; Riccardo Zucchi
Journal:  FASEB J       Date:  2007-02-06       Impact factor: 5.191

8.  Thyronamines are isozyme-specific substrates of deiodinases.

Authors:  S Piehl; T Heberer; G Balizs; T S Scanlan; R Smits; B Koksch; J Köhrle
Journal:  Endocrinology       Date:  2008-03-13       Impact factor: 4.736

9.  Thyronamines inhibit plasma membrane and vesicular monoamine transport.

Authors:  Aaron N Snead; Magda S Santos; Rebecca P Seal; Motonori Miyakawa; Robert H Edwards; Thomas S Scanlan
Journal:  ACS Chem Biol       Date:  2007-05-25       Impact factor: 5.100

10.  Novel thyroxine derivatives, thyronamine and 3-iodothyronamine, induce transient hypothermia and marked neuroprotection against stroke injury.

Authors:  Kristian P Doyle; Katherine L Suchland; Thomas M P Ciesielski; Nikola S Lessov; David K Grandy; Thomas S Scanlan; Mary P Stenzel-Poore
Journal:  Stroke       Date:  2007-08-09       Impact factor: 7.914
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  6 in total

1.  THE SYNTHESIS OF 13C9-15N-LABELED 3,5-DIIODOTHYRONINE AND THYROXINE.

Authors:  Sarah A Hackenmueller; Thomas S Scanlan
Journal:  Synth Commun       Date:  2012-06-05       Impact factor: 2.007

2.  Identification and quantification of 3-iodothyronamine metabolites in mouse serum using liquid chromatography-tandem mass spectrometry.

Authors:  Sarah A Hackenmueller; Thomas S Scanlan
Journal:  J Chromatogr A       Date:  2012-07-25       Impact factor: 4.759

Review 3.  Minireview: 3-Iodothyronamine (T1AM): a new player on the thyroid endocrine team?

Authors:  Thomas S Scanlan
Journal:  Endocrinology       Date:  2008-12-30       Impact factor: 4.736

4.  Quantitative Analysis of Thyroid Hormone Metabolites in Cell Culture Samples Using LC-MS/MS.

Authors:  Daniel Rathmann; Eddy Rijntjes; Julika Lietzow; Josef Köhrle
Journal:  Eur Thyroid J       Date:  2015-05-28

5.  Biosynthesis of 3-iodothyronamine (T1AM) is dependent on the sodium-iodide symporter and thyroperoxidase but does not involve extrathyroidal metabolism of T4.

Authors:  Sarah A Hackenmueller; Maja Marchini; Alessandro Saba; Riccardo Zucchi; Thomas S Scanlan
Journal:  Endocrinology       Date:  2012-09-04       Impact factor: 4.736

Review 6.  Torpor: The Rise and Fall of 3-Monoiodothyronamine from Brain to Gut-From Gut to Brain?

Authors:  Hartmut H Glossmann; Oliver M D Lutz
Journal:  Front Endocrinol (Lausanne)       Date:  2017-05-31       Impact factor: 5.555
  6 in total

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