Literature DB >> 18811208

Combinatorial libraries of bis-heterocyclic compounds with skeletal diversity.

Miroslav Soural1, Isabelle Bouillon, Viktor Krchnák.   

Abstract

Combinatorial solid-phase synthesis of <span class="Chemical">bis-heterocyclic compounds, characterized by the presence of two <class="Chemical">span class="Chemical">heterocyclic cores connected by a spacer of variable length/structure, provided structurally heterogeneous libraries with skeletal diversity. Both heterocyclic rings were assembled on resin in a combinatorial fashion.

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Year:  2008        PMID： 18811208      PMCID： PMC2633873          DOI： 10.1021/cc8001074

Source DB:  PubMed          Journal:  J Comb Chem        ISSN： 1520-4766


  12 in total

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Review 6.  Comprehensive survey of combinatorial library synthesis: 2003.

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  9 in total

1.  Combinatorial libraries of bis-heterocyclic compounds with skeletal diversity.

Authors:  Miroslav Soural; Isabelle Bouillon; Viktor Krchnák
Journal:  J Comb Chem       Date:  2008-09-24

2.  Polymer-supported alpha-acylamino ketones: preparation and application in syntheses of 1,2,4-trisubstituted-1H-imidazoles.

Authors:  Jan Kocí; Nadĕzda Pudelová; Viktor Krchnák
Journal:  J Comb Chem       Date:  2009 May-Jun

3.  Resins with identical specifications are not identical. Identifying a useful solid-phase resin.

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Journal:  J Comb Chem       Date:  2009-03-09

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5.  New tricks of well-known aminoazoles in isocyanide-based multicomponent reactions and antibacterial activity of the compounds synthesized.

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6.  Multicomponent Reaction Based Synthesis of 1-Tetrazolylimidazo[1,5- a]pyridines.

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7.  Solvent- and Catalyst-Free One-Pot Green Bound-Type Fused Bis-Heterocycles Synthesis via Groebke-Blackburn-Bienaymé Reaction/SNAr/Ring-Chain Azido-Tautomerization Strategy.

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8.  Doebner-type pyrazolopyridine carboxylic acids in an Ugi four-component reaction.

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9.  Synthesis of Bis-heteroaryls Using Grignard Reagents and Pyridylsulfonium Salts.

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Journal:  Org Lett       Date:  2021-11-16       Impact factor: 6.005
  9 in total

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