Literature DB >> 19125667

Resins with identical specifications are not identical. Identifying a useful solid-phase resin.

Isabelle Bouillon1, Miroslav Soural, Marvin J Miller, Viktor Krchnák.   

Abstract

The quality of the most commonly used support for solid-phase syntheses, polystyrene resin cross-linked with 1% of divinylbenzene, differs considerably even among different lots of resin from the same source. Determination of the swelling capacity of resins before carrying out solid-phase syntheses represents a very simple means of nondestructive presynthetic resin characterization.

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Year:  2009        PMID： 19125667      PMCID： PMC2765498          DOI： 10.1021/cc800143e

Source DB:  PubMed          Journal:  J Comb Chem        ISSN： 1520-4766


  7 in total

Review 1.  The properties of resin supports and their effects on solid-phase organic synthesis.

Authors:  B Yan
Journal:  Comb Chem High Throughput Screen       Date:  1998-12       Impact factor: 1.339

2.  Influence of resin cross-linking on solid-phase chemistry.

Authors:  S Rana; P White; M Bradley
Journal:  J Comb Chem       Date:  2001 Jan-Feb

3.  Effects of resin swelling and substitution on solid phase synthesis.

Authors:  K C Pugh; E J York; J M Stewart
Journal:  Int J Pept Protein Res       Date:  1992 Sep-Oct

Review 4.  Chemical synthesis of peptides and proteins.

Authors:  S B Kent
Journal:  Annu Rev Biochem       Date:  1988       Impact factor: 23.643

5.  Aggregation of resin-bound peptides during solid-phase peptide synthesis. Prediction of difficult sequences.

Authors:  V Krchnák; Z Flegelová; J Vágner
Journal:  Int J Pept Protein Res       Date:  1993-11

6.  Combinatorial libraries of bis-heterocyclic compounds with skeletal diversity.

Authors:  Miroslav Soural; Isabelle Bouillon; Viktor Krchnák
Journal:  J Comb Chem       Date:  2008-09-24

7.  Gel-phase 19F NMR spectral quality for resins commonly used in solid-phase organic synthesis; a study of peptide solid-phase glycosylations.

Authors:  Mickael Mogemark; Frida Gårdmo; Tobias Tengel; Jan Kihlberg; Mikael Elofsson
Journal:  Org Biomol Chem       Date:  2004-05-25       Impact factor: 3.876
  7 in total
  7 in total

Review 1.  Comprehensive survey of chemical libraries for drug discovery and chemical biology: 2009.

Authors:  Roland E Dolle; Bertrand Le Bourdonnec; Karin Worm; Guillermo A Morales; Craig J Thomas; Wei Zhang
Journal:  J Comb Chem       Date:  2010-10-05

2.  Synthesis of quinazolines from N-(2-nitrophenylsulfonyl)iminodiacetate and alpha-(2-nitrophenylsulfonyl)amino ketones via 2H-indazole 1-oxides.

Authors:  Sona Krupková; Greg A Slough; Viktor Krchnák
Journal:  J Org Chem       Date:  2010-07-02       Impact factor: 4.354

3.  Solid-phase synthesis of fusaricidin/LI-F class of cyclic lipopeptides: Guanidinylation of resin-bound peptidyl amines.

Authors:  Nina Bionda; Jean-Philippe Pitteloud; Predrag Cudic
Journal:  Biopolymers       Date:  2013-04       Impact factor: 2.505

4.  Solid-phase synthesis and chemical properties of 2-(2-amino/hydroxyethyl)-1-aryl-3,4-dihydropyrazino[1, 2-b]indazol-2-iums.

Authors:  Jan Kocí; Viktor Krchnák
Journal:  J Comb Chem       Date:  2010 Jan-Feb

5.  Polymer-supported alpha-acylamino ketones: preparation and application in syntheses of 1,2,4-trisubstituted-1H-imidazoles.

Authors:  Jan Kocí; Nadĕzda Pudelová; Viktor Krchnák
Journal:  J Comb Chem       Date:  2009 May-Jun

6.  Multiplicity of diverse heterocycles from polymer-supported alpha-acylamino ketones.

Authors:  Nadezda Pudelová; Viktor Krchnák
Journal:  J Comb Chem       Date:  2009 Sep-Oct

7.  Investigation of Parameters that Affect Resin Swelling in Green Solvents.

Authors:  Chidi Amadi-Kamalu; Holly Clarke; Matthew McRobie; James Mortimer; Michael North; Yanrui Ran; Anne Routledge; Dani Sibbald; Matthew Tickias; Kai Tse; Helen Willway
Journal:  ChemistryOpen       Date:  2020-04-03       Impact factor: 2.911
  7 in total

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