Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 The Current Status of Heterocyclic Combinatorial Libraries.

Literature DB >> 11848878

The Current Status of Heterocyclic Combinatorial Libraries.

Adel Nefzi¹, John M. Ostresh, Richard A. Houghten.

Abstract

Year: 1997 PMID： 11848878 DOI： 10.1021/cr960010b

Source DB: PubMed Journal: Chem Rev ISSN： 0009-2665 Impact factor: 60.622

Keyword Cloud
Cited

× No keyword cloud information.

28 in total

1. Use of combinatorial library screening to identify inhibitors of a bacterial two-component signal transduction kinase.

Authors: S Roychoudhury; S E Blondelle; S M Collins; M C Davis; H D McKeever; R A Houghten; C N Parker
Journal: Mol Divers Date: 1998 Impact factor: 2.943

2. An efficient, multicomponent approach for solvent-free synthesis of 2-amino-4H-chromene scaffold.

Authors: M Reza Naimi-Jamal; Sara Mashkouri; Ali Sharifi
Journal: Mol Divers Date: 2010-04-07 Impact factor: 2.943

3. Electrocatalytic multicomponent assembling of isatins, 3-methyl-2-pyrazolin-5-ones and malononitrile: facile and convenient way to functionalized spirocyclic [indole-3,4'-pyrano[2,3-c]pyrazole] system.

Authors: Michail N Elinson; Alexander S Dorofeev; Fedor M Miloserdov; Gennady I Nikishin
Journal: Mol Divers Date: 2008-12-02 Impact factor: 2.943

4. Mixture-based heterocyclic combinatorial positional scanning libraries: discovery of bicyclic guanidines having potent antifungal activities against Candida albicans and Cryptococcus neoformans.

Authors: S E Blondelle; E Crooks; J M Ostresh; R A Houghten
Journal: Antimicrob Agents Chemother Date: 1999-01 Impact factor: 5.191

5. Identification of two novel, potent, low-liability antinociceptive compounds from the direct in vivo screening of a large mixture-based combinatorial library.

Authors: Kate J Reilley; Marc Giulianotti; Colette T Dooley; Adel Nefzi; Jay P McLaughlin; Richard A Houghten
Journal: AAPS J Date: 2010-04-27 Impact factor: 4.009

10. Diversity-oriented synthesis of benzimidazole, benzoxazole, benzothiazole and quinazolin-4(3H)-one libraries via potassium persulfate-CuSO4-mediated oxidative coupling reactions of aldehydes in aqueous micelles.

Authors: Atul Kumar; Ram Awatar Maurya; Deepti Saxena
Journal: Mol Divers Date: 2009-07-04 Impact factor: 2.943

The Current Status of Heterocyclic Combinatorial Libraries.

1. Use of combinatorial library screening to identify inhibitors of a bacterial two-component signal transduction kinase.

2. An efficient, multicomponent approach for solvent-free synthesis of 2-amino-4H-chromene scaffold.

3. Electrocatalytic multicomponent assembling of isatins, 3-methyl-2-pyrazolin-5-ones and malononitrile: facile and convenient way to functionalized spirocyclic [indole-3,4'-pyrano[2,3-c]pyrazole] system.

4. Mixture-based heterocyclic combinatorial positional scanning libraries: discovery of bicyclic guanidines having potent antifungal activities against Candida albicans and Cryptococcus neoformans.

5. Identification of two novel, potent, low-liability antinociceptive compounds from the direct in vivo screening of a large mixture-based combinatorial library.

6. Combinatorial libraries of bis-heterocyclic compounds with skeletal diversity.

7. Solution phase synthesis of a diverse library of highly substituted isoxazoles.

8. A solid-phase approach towards the development of 3-aza-6,8-dioxabicyclo[3.2.1]octane scaffolds.

9. Parallel Synthesis of Structurally Diverse Aminobenzimidazole Tethered Sultams and Benzothiazepinones.

10. Diversity-oriented synthesis of benzimidazole, benzoxazole, benzothiazole and quinazolin-4(3H)-one libraries via potassium persulfate-CuSO4-mediated oxidative coupling reactions of aldehydes in aqueous micelles.