BACKGROUND: Many studies have investigated the Mediterranean diet as a risk factor for cancer, none of which has included cutaneous melanoma. The latter is usually fatal, rendering knowledge about prevention extremely important. We assessed the role of some food components of the Mediterranean diet and cutaneous melanoma. METHODS: A hospital-based case-control study was conducted in the inpatient wards of IDI-San Carlo Rome, Italy including 304 incident cases of cutaneous melanoma and 305 controls, frequency matched to cases. Information on socio-demographic characteristics, medical history, smoking, sun exposure, pigmentary characteristics and diet was collected. Logistic regression was the method used to estimated odds ratio and 95% CIs. RESULTS: After careful control for several sun exposure and pigmentary characteristics, we found a protective effect for weekly consumption of fish (OR, 0.65, 95%CI = 0.43-0.97), shellfish (OR, 0.53, 95%CI = 0.31-0.89), fish rich in n-3 fatty acids (OR, 0.52, 95%CI = 0.34-0.78), daily tea drinking (OR, 0.42, 95%CI, 0.18-0.95; P(trend) = 0.025) and high consumption of vegetables (OR, 0.50, 95%CI = 0.31-0.80, P(trend) = 0.005) in particular carrots, cruciferous and leafy vegetables and fruits (OR, 0.54, 95%CI =0.33-0.86, P(trend) = 0.013), in particular citrus fruits. No association was found for alcohol consumption and any other food items. CONCLUSION: Overall, our findings suggest that some dietary factors present in the Mediterranean diet might protect from cutaneous melanoma.
BACKGROUND: Many studies have investigated the Mediterranean diet as a risk factor for cancer, none of which has included cutaneous melanoma. The latter is usually fatal, rendering knowledge about prevention extremely important. We assessed the role of some food components of the Mediterranean diet and cutaneous melanoma. METHODS: A hospital-based case-control study was conducted in the inpatient wards of IDI-San Carlo Rome, Italy including 304 incident cases of cutaneous melanoma and 305 controls, frequency matched to cases. Information on socio-demographic characteristics, medical history, smoking, sun exposure, pigmentary characteristics and diet was collected. Logistic regression was the method used to estimated odds ratio and 95% CIs. RESULTS: After careful control for several sun exposure and pigmentary characteristics, we found a protective effect for weekly consumption of fish (OR, 0.65, 95%CI = 0.43-0.97), shellfish (OR, 0.53, 95%CI = 0.31-0.89), fish rich in n-3 fatty acids (OR, 0.52, 95%CI = 0.34-0.78), daily tea drinking (OR, 0.42, 95%CI, 0.18-0.95; P(trend) = 0.025) and high consumption of vegetables (OR, 0.50, 95%CI = 0.31-0.80, P(trend) = 0.005) in particular carrots, cruciferous and leafy vegetables and fruits (OR, 0.54, 95%CI =0.33-0.86, P(trend) = 0.013), in particular citrus fruits. No association was found for alcohol consumption and any other food items. CONCLUSION: Overall, our findings suggest that some dietary factors present in the Mediterranean diet might protect from cutaneous melanoma.
Authors: Susana Puig; Joaquim Marcoval; Cristina Paradelo; Antoni Azon; Ramon Bartralot; Susana Bel; Xavier Bigata; Aram Boada; Antoni Campoy; Cristina Carrera; Neus Curco; Joan Dalmau; Carlos Ferrándiz; Josep R Ferreres; Manel Formigon; Fernando Gallardo; Alberto Gonzalez; Miquel Just; Enric Llistosella; Rosa M Marti; M Elena Nogues; Ramon Pedragosa; Josep A Pujol; Rodrigo Roldán-Marín; Mireia Sabat; Montserrat Salleras; Juan A Smandia; Pedro Zaballos; Estel Plana; Josep Malvehy Journal: Acta Derm Venereol Date: 2015-04 Impact factor: 4.437
Authors: Kyoko Miura; Mandy Way; Zainab Jiyad; Louise Marquart; Elsemieke I Plasmeijer; Scott Campbell; Nicole Isbel; Jonathan Fawcett; Lisa E Ferguson; Marcia Davis; David C Whiteman; H Peter Soyer; Peter O'Rourke; Adèle C Green Journal: Eur J Nutr Date: 2020-09-09 Impact factor: 5.614
Authors: Liesbeth Sondermeijer; Lieke G E Lamboo; Anne C de Waal; Tessel E Galesloot; Lambertus A L M Kiemeney; Michelle van Rossum; Katja H Aben Journal: Dermatology Date: 2019-09-10 Impact factor: 5.366