Literature DB >> 17918848

Trisubstituted isoalloxazines as a new class of G-quadruplex binding ligands: small molecule regulation of c-kit oncogene expression.

Mallesham Bejugam1, Sven Sewitz, Pravin S Shirude, Raphaël Rodriguez, Ramla Shahid, Shankar Balasubramanian.   

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Year:  2007        PMID： 17918848      PMCID： PMC2195890          DOI： 10.1021/ja075881p

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


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  22 in total

1.  Telomere end-binding proteins control the formation of G-quadruplex DNA structures in vivo.

Authors:  Katrin Paeschke; Tomas Simonsson; Jan Postberg; Daniela Rhodes; Hans Joachim Lipps
Journal:  Nat Struct Mol Biol       Date:  2005-09-04       Impact factor: 15.369

2.  Evaluation of by disubstituted acridone derivatives as telomerase inhibitors: the importance of G-quadruplex binding.

Authors:  R John Harrison; Anthony P Reszka; Shozeb M Haider; Barbara Romagnoli; James Morrell; Martin A Read; Sharon M Gowan; Christopher M Incles; Lloyd R Kelland; Stephen Neidle
Journal:  Bioorg Med Chem Lett       Date:  2004-12-06       Impact factor: 2.823

3.  Expression of protooncogene c-kit and its ligand stem cell factor (SCF) in gastric carcinoma cell lines.

Authors:  S Hassan; Y Kinoshita; C Kawanami; K Kishi; Y Matsushima; A Ohashi; Y Funasaka; A Okada; T Maekawa; W He-Yao; T Chiba
Journal:  Dig Dis Sci       Date:  1998-01       Impact factor: 3.199

4.  Putative DNA quadruplex formation within the human c-kit oncogene.

Authors:  Sarah Rankin; Anthony P Reszka; Julian Huppert; Mire Zloh; Gary N Parkinson; Alan K Todd; Sylvain Ladame; Shankar Balasubramanian; Stephen Neidle
Journal:  J Am Chem Soc       Date:  2005-08-03       Impact factor: 15.419

5.  A conserved quadruplex motif located in a transcription activation site of the human c-kit oncogene.

Authors:  Himesh Fernando; Anthony P Reszka; Julian Huppert; Sylvain Ladame; Sarah Rankin; Ashok R Venkitaraman; Stephen Neidle; Shankar Balasubramanian
Journal:  Biochemistry       Date:  2006-06-27       Impact factor: 3.162

6.  Human proto-oncogene c-kit: a new cell surface receptor tyrosine kinase for an unidentified ligand.

Authors:  Y Yarden; W J Kuang; T Yang-Feng; L Coussens; S Munemitsu; T J Dull; E Chen; J Schlessinger; U Francke; A Ullrich
Journal:  EMBO J       Date:  1987-11       Impact factor: 11.598

7.  Facilitation of a structural transition in the polypurine/polypyrimidine tract within the proximal promoter region of the human VEGF gene by the presence of potassium and G-quadruplex-interactive agents.

Authors:  Daekyu Sun; Kexiao Guo; Jadrian J Rusche; Laurence H Hurley
Journal:  Nucleic Acids Res       Date:  2005-10-20       Impact factor: 16.971

8.  Highly prevalent putative quadruplex sequence motifs in human DNA.

Authors:  Alan K Todd; Matthew Johnston; Stephen Neidle
Journal:  Nucleic Acids Res       Date:  2005-05-24       Impact factor: 16.971

9.  G-quadruplex formation within the promoter of the KRAS proto-oncogene and its effect on transcription.

Authors:  Susanna Cogoi; Luigi E Xodo
Journal:  Nucleic Acids Res       Date:  2006-05-10       Impact factor: 16.971

10.  NMR solution structure of the major G-quadruplex structure formed in the human BCL2 promoter region.

Authors:  Jixun Dai; Ding Chen; Roger A Jones; Laurence H Hurley; Danzhou Yang
Journal:  Nucleic Acids Res       Date:  2006-09-22       Impact factor: 16.971
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  66 in total

1.  Molecular cloning of the human platelet-derived growth factor receptor beta (PDGFR-beta) promoter and drug targeting of the G-quadruplex-forming region to repress PDGFR-beta expression.

Authors:  Yong Qin; Jessica S Fortin; Denise Tye; Mary Gleason-Guzman; Tracy A Brooks; Laurence H Hurley
Journal:  Biochemistry       Date:  2010-05-18       Impact factor: 3.162

Review 2.  In vivo veritas: using yeast to probe the biological functions of G-quadruplexes.

Authors:  Jay E Johnson; Jasmine S Smith; Marina L Kozak; F Brad Johnson
Journal:  Biochimie       Date:  2008-02-21       Impact factor: 4.079

Review 3.  Structures, folding patterns, and functions of intramolecular DNA G-quadruplexes found in eukaryotic promoter regions.

Authors:  Yong Qin; Laurence H Hurley
Journal:  Biochimie       Date:  2008-02-29       Impact factor: 4.079

Review 4.  G-quadruplexes-novel mediators of gene function.

Authors:  Wenhua Zhou; Nigel J Brand; Liming Ying
Journal:  J Cardiovasc Transl Res       Date:  2011-02-08       Impact factor: 4.132

Review 5.  DNA secondary structures: stability and function of G-quadruplex structures.

Authors:  Matthew L Bochman; Katrin Paeschke; Virginia A Zakian
Journal:  Nat Rev Genet       Date:  2012-10-03       Impact factor: 53.242

6.  G-quadruplex nucleic acids as therapeutic targets.

Authors:  Shankar Balasubramanian; Stephen Neidle
Journal:  Curr Opin Chem Biol       Date:  2009-06-08       Impact factor: 8.822

7.  Solution structures of all parallel-stranded monomeric and dimeric G-quadruplex scaffolds of the human c-kit2 promoter.

Authors:  Vitaly Kuryavyi; Anh Tuân Phan; Dinshaw J Patel
Journal:  Nucleic Acids Res       Date:  2010-06-21       Impact factor: 16.971

8.  Molecular models for intrastrand DNA G-quadruplexes.

Authors:  Federico Fogolari; Haritha Haridas; Alessandra Corazza; Paolo Viglino; Davide Corà; Michele Caselle; Gennaro Esposito; Luigi E Xodo
Journal:  BMC Struct Biol       Date:  2009-10-07

9.  Altered gene expression in the Werner and Bloom syndromes is associated with sequences having G-quadruplex forming potential.

Authors:  Jay E Johnson; Kajia Cao; Paul Ryvkin; Li-San Wang; F Brad Johnson
Journal:  Nucleic Acids Res       Date:  2009-12-04       Impact factor: 16.971

10.  Genome-wide analysis of a G-quadruplex-specific single-chain antibody that regulates gene expression.

Authors:  Himesh Fernando; Sven Sewitz; Jeremy Darot; Simon Tavaré; Julian Leon Huppert; Shankar Balasubramanian
Journal:  Nucleic Acids Res       Date:  2009-09-10       Impact factor: 16.971
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