| Literature DB >> 17884492 |
George P Lahm1, Thomas M Stevenson, Thomas P Selby, John H Freudenberger, Daniel Cordova, Lindsey Flexner, Cheryl A Bellin, Christine M Dubas, Ben K Smith, Kenneth A Hughes, J Gary Hollingshaus, Christopher E Clark, Eric A Benner.
Abstract
Rynaxypyr is a highly potent and selective activator of insect ryanodine receptors with exceptional activity on a broad range of Lepidoptera. A strong correlation between insecticidal activity and ryanodine receptor activation is observed along with selective activity against insect over mammalian receptors. The synthesis and biological results are presented.Entities:
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Year: 2007 PMID： 17884492 DOI： 10.1016/j.bmcl.2007.09.012
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823